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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C3orf25
Full Name:
EF-hand domain-containing protein C3orf25
Alias:
CC025; chromosome 3 open reading frame 25; LOC90288
Type:
Unknown function
Mass (Da):
66550
Number AA:
UniProt ID:
Q6NXP0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
D
D
D
Y
E
A
Y
H
S
L
F
L
S
L
Site 2
S10
D
D
Y
E
A
Y
H
S
L
F
L
S
L
L
G
Site 3
S21
S
L
L
G
L
C
P
S
K
T
P
I
N
E
N
Site 4
T23
L
G
L
C
P
S
K
T
P
I
N
E
N
A
P
Site 5
T55
K
D
F
R
L
P
Q
T
R
R
R
I
I
M
V
Site 6
T69
V
P
R
K
E
D
Q
T
P
L
N
P
A
S
Q
Site 7
S75
Q
T
P
L
N
P
A
S
Q
P
Q
A
P
P
K
Site 8
S86
A
P
P
K
P
I
P
S
F
K
V
L
E
A
R
Site 9
T104
E
Q
P
E
D
R
K
T
W
L
S
Q
R
S
K
Site 10
S107
E
D
R
K
T
W
L
S
Q
R
S
K
L
R
Q
Site 11
S110
K
T
W
L
S
Q
R
S
K
L
R
Q
E
L
E
Site 12
S118
K
L
R
Q
E
L
E
S
F
G
D
V
K
R
W
Site 13
S131
R
W
L
E
N
K
P
S
I
T
P
S
E
A
K
Site 14
T133
L
E
N
K
P
S
I
T
P
S
E
A
K
V
L
Site 15
S135
N
K
P
S
I
T
P
S
E
A
K
V
L
H
M
Site 16
T160
A
S
Q
A
T
T
R
T
T
R
K
K
A
P
R
Site 17
T161
S
Q
A
T
T
R
T
T
R
K
K
A
P
R
L
Site 18
S169
R
K
K
A
P
R
L
S
R
L
S
R
Q
M
V
Site 19
S172
A
P
R
L
S
R
L
S
R
Q
M
V
P
Q
L
Site 20
S192
P
A
L
S
V
M
Y
S
Y
L
H
S
R
K
I
Site 21
Y193
A
L
S
V
M
Y
S
Y
L
H
S
R
K
I
K
Site 22
S196
V
M
Y
S
Y
L
H
S
R
K
I
K
I
L
E
Site 23
T217
Q
G
E
N
Q
R
I
T
R
E
E
F
I
A
A
Site 24
S273
S
M
A
Q
Q
R
S
S
L
A
T
A
R
E
H
Site 25
T276
Q
Q
R
S
S
L
A
T
A
R
E
H
Y
I
L
Site 26
Y281
L
A
T
A
R
E
H
Y
I
L
A
K
H
R
D
Site 27
S289
I
L
A
K
H
R
D
S
L
K
G
P
L
K
K
Site 28
S301
L
K
K
Q
E
V
D
S
A
P
Q
L
P
K
V
Site 29
T326
Q
M
E
T
R
P
M
T
L
E
E
M
E
E
V
Site 30
T347
R
Q
R
Q
H
K
L
T
I
P
S
I
Q
Y
T
Site 31
T354
T
I
P
S
I
Q
Y
T
E
Q
C
H
L
V
R
Site 32
S386
D
M
R
E
L
I
D
S
A
R
R
H
N
F
L
Site 33
Y405
C
W
K
L
C
K
S
Y
G
L
P
L
T
E
D
Site 34
T410
K
S
Y
G
L
P
L
T
E
D
I
L
M
K
A
Site 35
Y441
P
I
R
Q
P
G
G
Y
Y
S
D
W
K
V
F
Site 36
S443
R
Q
P
G
G
Y
Y
S
D
W
K
V
F
S
P
Site 37
S449
Y
S
D
W
K
V
F
S
P
N
L
A
L
L
R
Site 38
S457
P
N
L
A
L
L
R
S
Q
G
P
G
K
S
K
Site 39
S463
R
S
Q
G
P
G
K
S
K
R
T
D
K
K
T
Site 40
T470
S
K
R
T
D
K
K
T
P
K
K
S
K
K
M
Site 41
S474
D
K
K
T
P
K
K
S
K
K
M
R
F
K
E
Site 42
S494
R
K
L
K
V
K
R
S
S
G
L
Q
Q
T
H
Site 43
S495
K
L
K
V
K
R
S
S
G
L
Q
Q
T
H
P
Site 44
T500
R
S
S
G
L
Q
Q
T
H
P
N
S
F
W
P
Site 45
Y540
V
Q
H
Q
P
H
V
Y
P
A
T
Y
H
P
D
Site 46
Y557
W
P
L
R
N
K
N
Y
M
T
H
A
H
Y
D
Site 47
Y563
N
Y
M
T
H
A
H
Y
D
A
A
K
V
Y
Y
Site 48
Y569
H
Y
D
A
A
K
V
Y
Y
I
N
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation