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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRMT10
Full Name:
Putative protein arginine N-methyltransferase 10
Alias:
Type:
Mass (Da):
94501
Number AA:
845
UniProt ID:
Q6P2P2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
N
S
R
P
R
S
R
R
D
A
G
G
G
Site 2
S26
A
G
R
D
E
L
V
S
R
S
L
Q
S
A
E
Site 3
S28
R
D
E
L
V
S
R
S
L
Q
S
A
E
H
C
Site 4
T65
L
K
H
D
V
K
E
T
F
Q
Y
T
L
F
R
Site 5
Y68
D
V
K
E
T
F
Q
Y
T
L
F
R
W
A
E
Site 6
Y123
F
R
D
E
A
A
G
Y
F
H
K
A
V
K
L
Site 7
S135
V
K
L
N
P
D
F
S
D
A
K
E
N
F
Y
Site 8
T164
L
N
D
T
K
R
N
T
I
Y
N
A
A
I
Q
Site 9
S192
G
A
G
T
G
I
L
S
M
F
A
K
K
A
G
Site 10
S202
A
K
K
A
G
A
H
S
V
Y
A
C
E
L
S
Site 11
Y204
K
A
G
A
H
S
V
Y
A
C
E
L
S
K
T
Site 12
S236
I
K
L
L
H
T
K
S
L
D
I
E
I
P
K
Site 13
T283
H
L
L
L
Q
P
K
T
K
G
E
S
A
N
C
Site 14
Y293
E
S
A
N
C
E
K
Y
G
K
V
I
P
A
S
Site 15
S337
P
T
N
V
K
F
Q
S
P
A
Y
S
S
V
D
Site 16
S341
K
F
Q
S
P
A
Y
S
S
V
D
T
E
E
T
Site 17
S342
F
Q
S
P
A
Y
S
S
V
D
T
E
E
T
I
Site 18
T345
P
A
Y
S
S
V
D
T
E
E
T
I
E
P
Y
Site 19
T348
S
S
V
D
T
E
E
T
I
E
P
Y
T
T
E
Site 20
T353
E
E
T
I
E
P
Y
T
T
E
K
M
S
R
V
Site 21
T354
E
T
I
E
P
Y
T
T
E
K
M
S
R
V
P
Site 22
S358
P
Y
T
T
E
K
M
S
R
V
P
G
G
Y
L
Site 23
S386
N
N
L
Q
E
L
K
S
L
A
T
K
K
P
D
Site 24
S421
L
Q
L
D
D
E
H
S
L
S
T
S
P
S
E
Site 25
S423
L
D
D
E
H
S
L
S
T
S
P
S
E
E
T
Site 26
S425
D
E
H
S
L
S
T
S
P
S
E
E
T
C
W
Site 27
S427
H
S
L
S
T
S
P
S
E
E
T
C
W
E
Q
Site 28
Y437
T
C
W
E
Q
A
V
Y
P
V
Q
D
L
A
D
Site 29
Y445
P
V
Q
D
L
A
D
Y
W
I
K
P
G
D
H
Site 30
Y463
E
V
S
C
Q
D
C
Y
L
R
I
Q
S
I
S
Site 31
S483
C
E
M
D
V
A
K
S
F
T
Q
N
K
D
L
Site 32
Y533
A
L
L
N
N
I
P
Y
H
E
G
F
K
M
A
Site 33
S547
A
M
S
K
V
L
S
S
L
T
P
E
K
L
Y
Site 34
T549
S
K
V
L
S
S
L
T
P
E
K
L
Y
Q
T
Site 35
Y554
S
L
T
P
E
K
L
Y
Q
T
M
D
T
H
C
Site 36
T574
S
G
T
G
Q
S
N
T
V
Q
N
I
L
E
P
Site 37
S608
L
G
Q
V
K
P
Y
S
S
V
E
K
D
Q
H
Site 38
S609
G
Q
V
K
P
Y
S
S
V
E
K
D
Q
H
R
Site 39
S623
R
I
A
L
D
L
I
S
E
A
N
H
F
P
K
Site 40
S652
A
M
L
Q
R
P
K
S
D
K
L
W
S
I
I
Site 41
T763
L
L
R
L
D
L
M
T
P
Y
L
N
T
S
N
Site 42
Y765
R
L
D
L
M
T
P
Y
L
N
T
S
N
R
E
Site 43
S769
M
T
P
Y
L
N
T
S
N
R
E
V
K
V
Y
Site 44
Y776
S
N
R
E
V
K
V
Y
V
C
K
S
G
R
L
Site 45
T802
D
E
E
I
R
L
D
T
S
S
E
A
S
H
W
Site 46
S803
E
E
I
R
L
D
T
S
S
E
A
S
H
W
K
Site 47
S804
E
I
R
L
D
T
S
S
E
A
S
H
W
K
Q
Site 48
S807
L
D
T
S
S
E
A
S
H
W
K
Q
A
A
V
Site 49
S831
M
G
E
E
L
V
L
S
I
Q
H
H
K
S
N
Site 50
S837
L
S
I
Q
H
H
K
S
N
V
S
I
T
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation