KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DENND1B
Full Name:
DENN domain-containing protein 1B
Alias:
Protein FAM31B
Type:
Mass (Da):
48260
Number AA:
426
UniProt ID:
Q6P3S1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
T
K
A
N
P
D
R
T
F
D
L
V
L
K
V
Site 2
S24
L
K
V
K
C
H
A
S
E
N
E
D
P
V
V
Site 3
S47
G
D
Q
E
I
L
Q
S
V
P
K
F
C
F
P
Site 4
S61
P
F
D
V
E
R
V
S
Q
N
Q
V
G
Q
H
Site 5
T70
N
Q
V
G
Q
H
F
T
F
V
L
T
D
I
E
Site 6
T74
Q
H
F
T
F
V
L
T
D
I
E
S
K
Q
R
Site 7
Y117
L
L
N
T
L
A
D
Y
L
A
K
E
L
E
N
Site 8
T129
L
E
N
D
L
N
E
T
L
R
S
L
Y
N
H
Site 9
S132
D
L
N
E
T
L
R
S
L
Y
N
H
P
V
P
Site 10
Y134
N
E
T
L
R
S
L
Y
N
H
P
V
P
K
A
Site 11
T143
H
P
V
P
K
A
N
T
P
V
N
L
S
V
N
Site 12
T183
P
D
V
T
G
L
P
T
I
P
E
S
R
N
L
Site 13
S187
G
L
P
T
I
P
E
S
R
N
L
T
E
Y
F
Site 14
T191
I
P
E
S
R
N
L
T
E
Y
F
V
A
V
D
Site 15
Y193
E
S
R
N
L
T
E
Y
F
V
A
V
D
V
N
Site 16
Y206
V
N
N
M
L
Q
L
Y
A
S
M
L
H
E
R
Site 17
S208
N
M
L
Q
L
Y
A
S
M
L
H
E
R
R
I
Site 18
S279
I
E
R
V
K
N
K
S
L
E
D
V
V
M
L
Site 19
T292
M
L
N
V
D
T
N
T
L
E
S
P
F
S
D
Site 20
S295
V
D
T
N
T
L
E
S
P
F
S
D
L
N
N
Site 21
S298
N
T
L
E
S
P
F
S
D
L
N
N
L
P
S
Site 22
S305
S
D
L
N
N
L
P
S
D
V
V
S
A
L
K
Site 23
S309
N
L
P
S
D
V
V
S
A
L
K
N
K
L
K
Site 24
S340
A
Q
A
A
L
F
G
S
Y
R
D
A
L
R
Y
Site 25
Y347
S
Y
R
D
A
L
R
Y
K
P
G
E
P
I
T
Site 26
T354
Y
K
P
G
E
P
I
T
F
C
E
E
S
F
V
Site 27
S359
P
I
T
F
C
E
E
S
F
V
K
H
R
S
S
Site 28
S366
S
F
V
K
H
R
S
S
V
M
K
Q
F
L
E
Site 29
S399
L
N
A
G
R
G
F
S
D
V
F
E
E
E
I
Site 30
T407
D
V
F
E
E
E
I
T
S
G
G
F
C
G
G
Site 31
S408
V
F
E
E
E
I
T
S
G
G
F
C
G
G
K
Site 32
Y420
G
G
K
D
K
L
Q
Y
D
Y
P
F
S
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation