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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO42
Full Name:
F-box only protein 42
Alias:
F-box 42; F-box only 42; F-box protein 42; Fbx42; Just one F-box and Kelch domain-containing protein; KIAA1332
Type:
Mass (Da):
77839
Number AA:
717
UniProt ID:
Q6P3S6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
S
S
S
D
S
E
D
D
S
F
Site 2
S7
_
M
A
S
S
S
D
S
E
D
D
S
F
M
A
Site 3
S11
S
S
D
S
E
D
D
S
F
M
A
V
D
Q
E
Site 4
T41
P
V
L
E
A
E
E
T
R
H
N
R
S
M
S
Site 5
S46
E
E
T
R
H
N
R
S
M
S
E
L
P
E
E
Site 6
S48
T
R
H
N
R
S
M
S
E
L
P
E
E
V
L
Site 7
S63
E
Y
I
L
S
F
L
S
P
Y
Q
E
H
K
T
Site 8
Y65
I
L
S
F
L
S
P
Y
Q
E
H
K
T
A
A
Site 9
Y90
K
G
V
A
H
Q
C
Y
H
G
F
M
K
A
V
Site 10
Y109
I
Q
W
E
S
R
T
Y
P
Y
P
G
T
P
I
Site 11
T114
R
T
Y
P
Y
P
G
T
P
I
T
Q
R
F
S
Site 12
T117
P
Y
P
G
T
P
I
T
Q
R
F
S
H
S
A
Site 13
Y126
R
F
S
H
S
A
C
Y
Y
D
A
N
Q
S
M
Site 14
Y127
F
S
H
S
A
C
Y
Y
D
A
N
Q
S
M
Y
Site 15
Y134
Y
D
A
N
Q
S
M
Y
V
F
G
G
C
T
Q
Site 16
S158
L
W
R
L
D
L
N
S
K
E
W
I
R
P
L
Site 17
S167
E
W
I
R
P
L
A
S
G
S
Y
P
S
P
K
Site 18
S169
I
R
P
L
A
S
G
S
Y
P
S
P
K
A
G
Site 19
Y170
R
P
L
A
S
G
S
Y
P
S
P
K
A
G
A
Site 20
S172
L
A
S
G
S
Y
P
S
P
K
A
G
A
T
L
Site 21
S196
F
G
G
W
T
R
P
S
P
Y
P
L
H
Q
P
Site 22
Y198
G
W
T
R
P
S
P
Y
P
L
H
Q
P
E
R
Site 23
T212
R
F
F
D
E
I
H
T
Y
S
P
S
K
N
W
Site 24
S257
S
L
G
S
R
Q
M
S
N
D
V
W
V
L
D
Site 25
S276
A
W
S
K
P
N
I
S
G
P
S
P
H
P
R
Site 26
S279
K
P
N
I
S
G
P
S
P
H
P
R
G
G
Q
Site 27
S287
P
H
P
R
G
G
Q
S
Q
I
V
I
D
D
A
Site 28
S365
P
S
G
R
A
P
L
S
P
S
L
N
S
R
P
Site 29
S367
G
R
A
P
L
S
P
S
L
N
S
R
P
S
P
Site 30
S370
P
L
S
P
S
L
N
S
R
P
S
P
I
S
A
Site 31
S373
P
S
L
N
S
R
P
S
P
I
S
A
T
P
P
Site 32
S376
N
S
R
P
S
P
I
S
A
T
P
P
A
L
V
Site 33
T378
R
P
S
P
I
S
A
T
P
P
A
L
V
P
E
Site 34
T386
P
P
A
L
V
P
E
T
R
E
Y
R
S
Q
S
Site 35
Y389
L
V
P
E
T
R
E
Y
R
S
Q
S
P
V
R
Site 36
S391
P
E
T
R
E
Y
R
S
Q
S
P
V
R
S
M
Site 37
S393
T
R
E
Y
R
S
Q
S
P
V
R
S
M
D
E
Site 38
S397
R
S
Q
S
P
V
R
S
M
D
E
A
P
C
V
Site 39
T410
C
V
N
G
R
W
G
T
L
R
P
R
A
Q
R
Site 40
T419
R
P
R
A
Q
R
Q
T
P
S
G
S
R
E
G
Site 41
S421
R
A
Q
R
Q
T
P
S
G
S
R
E
G
S
L
Site 42
S423
Q
R
Q
T
P
S
G
S
R
E
G
S
L
S
P
Site 43
S427
P
S
G
S
R
E
G
S
L
S
P
A
R
G
D
Site 44
S429
G
S
R
E
G
S
L
S
P
A
R
G
D
G
S
Site 45
S436
S
P
A
R
G
D
G
S
P
I
L
N
G
G
S
Site 46
S454
G
T
A
A
V
G
G
S
S
L
D
S
P
V
Q
Site 47
S464
D
S
P
V
Q
A
I
S
P
S
T
P
S
A
P
Site 48
S466
P
V
Q
A
I
S
P
S
T
P
S
A
P
E
G
Site 49
T467
V
Q
A
I
S
P
S
T
P
S
A
P
E
G
Y
Site 50
S481
Y
D
L
K
I
G
L
S
L
A
P
R
R
G
S
Site 51
S488
S
L
A
P
R
R
G
S
L
P
D
Q
K
D
L
Site 52
S499
Q
K
D
L
R
L
G
S
I
D
L
N
W
D
L
Site 53
S510
N
W
D
L
K
P
A
S
S
S
N
P
M
D
G
Site 54
S511
W
D
L
K
P
A
S
S
S
N
P
M
D
G
M
Site 55
S512
D
L
K
P
A
S
S
S
N
P
M
D
G
M
D
Site 56
T522
M
D
G
M
D
N
R
T
V
G
G
S
M
R
H
Site 57
S526
D
N
R
T
V
G
G
S
M
R
H
P
P
E
Q
Site 58
T539
E
Q
T
N
G
V
H
T
P
P
H
V
A
S
A
Site 59
S545
H
T
P
P
H
V
A
S
A
L
A
G
A
V
S
Site 60
S552
S
A
L
A
G
A
V
S
P
G
A
L
R
R
S
Site 61
S559
S
P
G
A
L
R
R
S
L
E
A
I
K
A
M
Site 62
S568
E
A
I
K
A
M
S
S
K
G
P
S
A
S
A
Site 63
S572
A
M
S
S
K
G
P
S
A
S
A
A
L
S
P
Site 64
S574
S
S
K
G
P
S
A
S
A
A
L
S
P
P
L
Site 65
S578
P
S
A
S
A
A
L
S
P
P
L
G
S
S
P
Site 66
S583
A
L
S
P
P
L
G
S
S
P
G
S
P
G
S
Site 67
S584
L
S
P
P
L
G
S
S
P
G
S
P
G
S
Q
Site 68
S587
P
L
G
S
S
P
G
S
P
G
S
Q
S
L
S
Site 69
S590
S
S
P
G
S
P
G
S
Q
S
L
S
S
G
E
Site 70
S592
P
G
S
P
G
S
Q
S
L
S
S
G
E
T
V
Site 71
S594
S
P
G
S
Q
S
L
S
S
G
E
T
V
P
I
Site 72
S595
P
G
S
Q
S
L
S
S
G
E
T
V
P
I
P
Site 73
T598
Q
S
L
S
S
G
E
T
V
P
I
P
R
P
G
Site 74
S613
P
A
Q
G
D
G
H
S
L
P
P
I
A
R
R
Site 75
S628
L
G
H
H
P
P
Q
S
L
N
V
G
K
P
L
Site 76
Y636
L
N
V
G
K
P
L
Y
Q
S
M
N
C
K
P
Site 77
Y647
N
C
K
P
M
Q
M
Y
V
L
D
I
K
D
T
Site 78
T654
Y
V
L
D
I
K
D
T
K
E
K
G
R
V
K
Site 79
S667
V
K
W
K
V
F
N
S
S
S
V
V
G
P
P
Site 80
S669
W
K
V
F
N
S
S
S
V
V
G
P
P
E
T
Site 81
T680
P
P
E
T
S
L
H
T
V
V
Q
G
R
G
E
Site 82
Y703
D
K
K
Q
N
V
K
Y
Y
P
K
T
N
A
L
Site 83
Y704
K
K
Q
N
V
K
Y
Y
P
K
T
N
A
L
Y
Site 84
Y711
Y
P
K
T
N
A
L
Y
F
V
R
A
K
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation