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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NBPF10
Full Name:
Neuroblastoma breakpoint family member 10
Alias:
NBPFA
Type:
Mass (Da):
96426
Number AA:
841
UniProt ID:
Q6P3W6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
V
V
S
A
G
P
W
S
S
E
K
A
E
M
N
Site 2
S10
V
S
A
G
P
W
S
S
E
K
A
E
M
N
I
Site 3
Y58
L
A
N
Q
Q
K
K
Y
N
Y
E
E
C
K
D
Site 4
Y95
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
S
Q
Site 5
S101
Q
Y
K
V
L
V
H
S
Q
E
R
E
L
T
Q
Site 6
T107
H
S
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 7
S120
L
R
E
G
R
D
A
S
R
S
L
N
E
H
L
Site 8
S122
E
G
R
D
A
S
R
S
L
N
E
H
L
Q
A
Site 9
T132
E
H
L
Q
A
L
L
T
L
D
E
P
D
K
S
Site 10
S139
T
L
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 11
S163
Q
H
L
V
Q
K
L
S
P
E
N
D
E
D
E
Site 12
S185
E
A
E
K
V
Q
K
S
S
A
P
R
E
V
Q
Site 13
S186
A
E
K
V
Q
K
S
S
A
P
R
E
V
Q
K
Site 14
T194
A
P
R
E
V
Q
K
T
E
E
S
K
V
P
E
Site 15
S197
E
V
Q
K
T
E
E
S
K
V
P
E
D
S
L
Site 16
S203
E
S
K
V
P
E
D
S
L
E
E
C
A
I
T
Site 17
T210
S
L
E
E
C
A
I
T
C
S
N
S
H
G
P
Site 18
T230
P
H
K
N
I
K
I
T
F
E
E
D
E
V
N
Site 19
T239
E
E
D
E
V
N
S
T
L
V
V
D
R
E
S
Site 20
S246
T
L
V
V
D
R
E
S
S
H
D
E
C
Q
D
Site 21
S247
L
V
V
D
R
E
S
S
H
D
E
C
Q
D
A
Site 22
S280
V
V
S
A
G
P
L
S
S
E
K
A
E
M
N
Site 23
S281
V
S
A
G
P
L
S
S
E
K
A
E
M
N
I
Site 24
Y331
N
Q
Q
K
K
Y
K
Y
E
E
C
K
D
L
I
Site 25
S340
E
C
K
D
L
I
K
S
M
L
R
N
E
R
Q
Site 26
Y366
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
A
Q
Site 27
T378
H
A
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 28
T403
E
H
L
Q
A
L
L
T
P
D
E
P
D
K
S
Site 29
S410
T
P
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 30
S434
Q
H
L
V
Q
K
L
S
P
E
N
D
N
D
D
Site 31
S456
L
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
Site 32
S457
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
K
Site 33
S474
E
K
E
V
P
E
D
S
Q
E
E
C
A
I
T
Site 34
T481
S
Q
E
E
C
A
I
T
Y
S
N
S
H
G
P
Site 35
Y482
Q
E
E
C
A
I
T
Y
S
N
S
H
G
P
Y
Site 36
Y489
Y
S
N
S
H
G
P
Y
D
S
N
Q
P
H
R
Site 37
S491
N
S
H
G
P
Y
D
S
N
Q
P
H
R
K
T
Site 38
T498
S
N
Q
P
H
R
K
T
K
I
T
F
E
E
D
Site 39
T501
P
H
R
K
T
K
I
T
F
E
E
D
K
V
D
Site 40
S509
F
E
E
D
K
V
D
S
T
L
I
G
S
S
S
Site 41
T510
E
E
D
K
V
D
S
T
L
I
G
S
S
S
H
Site 42
S516
S
T
L
I
G
S
S
S
H
V
E
W
E
D
A
Site 43
S544
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 44
S551
S
P
R
N
L
Q
E
S
E
E
E
E
V
P
Q
Site 45
S560
E
E
E
V
P
Q
E
S
W
D
E
G
Y
S
T
Site 46
Y565
Q
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
Site 47
S566
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
Site 48
T567
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
M
Site 49
S569
D
E
G
Y
S
T
L
S
I
P
P
E
M
L
A
Site 50
S577
I
P
P
E
M
L
A
S
Y
Q
S
Y
S
S
T
Site 51
Y578
P
P
E
M
L
A
S
Y
Q
S
Y
S
S
T
F
Site 52
S580
E
M
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
Site 53
Y581
M
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
Site 54
S582
L
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
Site 55
S583
A
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
E
Site 56
T584
S
Y
Q
S
Y
S
S
T
F
H
S
L
E
E
Q
Site 57
S587
S
Y
S
S
T
F
H
S
L
E
E
Q
Q
V
C
Site 58
S620
E
A
T
G
P
R
L
S
R
E
L
L
D
E
K
Site 59
S635
G
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 60
Y640
Q
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
Site 61
S641
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
Site 62
T642
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
L
Site 63
S644
D
R
C
Y
S
T
P
S
G
C
L
E
L
T
D
Site 64
T650
P
S
G
C
L
E
L
T
D
S
C
Q
P
Y
R
Site 65
S652
G
C
L
E
L
T
D
S
C
Q
P
Y
R
S
A
Site 66
Y656
L
T
D
S
C
Q
P
Y
R
S
A
F
Y
V
L
Site 67
Y661
Q
P
Y
R
S
A
F
Y
V
L
E
Q
Q
R
V
Site 68
Y680
D
M
D
E
I
E
K
Y
Q
E
V
E
E
D
Q
Site 69
S690
V
E
E
D
Q
D
P
S
C
P
R
L
S
R
E
Site 70
S695
D
P
S
C
P
R
L
S
R
E
L
L
D
E
K
Site 71
S710
E
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 72
Y715
Q
D
S
L
D
R
C
Y
S
T
P
S
G
Y
L
Site 73
S716
D
S
L
D
R
C
Y
S
T
P
S
G
Y
L
E
Site 74
T717
S
L
D
R
C
Y
S
T
P
S
G
Y
L
E
L
Site 75
Y731
L
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
Site 76
S732
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
Site 77
S733
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
E
Site 78
S737
P
Y
S
S
A
V
Y
S
L
E
E
Q
Y
L
G
Site 79
S770
G
P
P
C
P
R
L
S
R
E
L
L
E
V
V
Site 80
Y790
Q
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
Site 81
S791
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Site 82
T792
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Q
Site 83
S795
R
C
Y
S
T
P
S
S
C
L
E
Q
P
D
S
Site 84
S802
S
C
L
E
Q
P
D
S
C
Q
P
Y
G
S
S
Site 85
Y806
Q
P
D
S
C
Q
P
Y
G
S
S
F
Y
A
L
Site 86
S809
S
C
Q
P
Y
G
S
S
F
Y
A
L
E
E
K
Site 87
S821
E
E
K
H
V
G
F
S
L
D
V
G
E
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation