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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLJ20272
Full Name:
Tetratricopeptide repeat protein 27
Alias:
Tetratricopeptide repeat domain 27; TTC27
Type:
Unknown function
Mass (Da):
96632
Number AA:
843
UniProt ID:
Q6P3X3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
W
T
P
E
L
A
I
L
R
Site 2
T14
A
I
L
R
G
F
P
T
E
A
E
R
Q
Q
W
Site 3
S29
K
Q
E
G
V
V
G
S
E
S
G
S
F
L
Q
Site 4
S68
T
A
E
E
K
I
D
S
Y
L
E
K
Q
V
V
Site 5
Y69
A
E
E
K
I
D
S
Y
L
E
K
Q
V
V
T
Site 6
T76
Y
L
E
K
Q
V
V
T
F
L
D
Y
S
T
D
Site 7
Y80
Q
V
V
T
F
L
D
Y
S
T
D
L
D
T
T
Site 8
T86
D
Y
S
T
D
L
D
T
T
E
R
Q
Q
L
I
Site 9
T87
Y
S
T
D
L
D
T
T
E
R
Q
Q
L
I
F
Site 10
T176
V
N
V
R
H
K
L
T
A
I
Q
S
L
P
W
Site 11
S225
Q
N
L
F
V
D
D
S
G
R
Y
L
A
I
Q
Site 12
Y243
E
C
A
Y
V
F
L
Y
Y
Y
E
Y
R
K
A
Site 13
Y244
C
A
Y
V
F
L
Y
Y
Y
E
Y
R
K
A
K
Site 14
Y245
A
Y
V
F
L
Y
Y
Y
E
Y
R
K
A
K
D
Site 15
T268
S
Q
L
Q
I
D
L
T
G
A
L
G
K
R
T
Site 16
Y281
R
T
R
F
Q
E
N
Y
V
A
Q
L
I
L
D
Site 17
S297
R
R
E
G
D
V
L
S
N
C
E
F
T
P
A
Site 18
T302
V
L
S
N
C
E
F
T
P
A
P
T
P
Q
E
Site 19
T306
C
E
F
T
P
A
P
T
P
Q
E
H
L
T
K
Site 20
T312
P
T
P
Q
E
H
L
T
K
N
L
E
L
N
D
Site 21
T321
N
L
E
L
N
D
D
T
I
L
N
D
I
K
L
Site 22
S399
R
T
K
L
E
K
G
S
T
R
R
V
E
R
A
Site 23
T400
T
K
L
E
K
G
S
T
R
R
V
E
R
A
M
Site 24
T410
V
E
R
A
M
R
Q
T
Q
A
L
A
D
Q
F
Site 25
T421
A
D
Q
F
E
D
K
T
T
S
V
L
E
R
L
Site 26
T422
D
Q
F
E
D
K
T
T
S
V
L
E
R
L
K
Site 27
Y476
W
E
D
V
V
I
C
Y
E
R
A
G
Q
H
G
Site 28
T498
Q
E
L
E
K
K
E
T
P
S
L
Y
C
L
L
Site 29
S500
L
E
K
K
E
T
P
S
L
Y
C
L
L
G
D
Site 30
S522
Y
D
K
A
W
E
L
S
R
Y
R
S
A
R
A
Site 31
Y524
K
A
W
E
L
S
R
Y
R
S
A
R
A
Q
R
Site 32
S526
W
E
L
S
R
Y
R
S
A
R
A
Q
R
S
K
Site 33
Y577
A
Y
L
A
L
E
D
Y
Q
G
S
A
K
A
F
Site 34
T589
K
A
F
Q
R
C
V
T
L
E
P
D
N
A
E
Site 35
S602
A
E
A
W
N
N
L
S
T
S
Y
I
R
L
K
Site 36
Y662
L
L
D
L
R
D
K
Y
K
D
V
Q
V
L
K
Site 37
T680
R
A
V
I
D
G
M
T
D
R
S
G
D
V
A
Site 38
S683
I
D
G
M
T
D
R
S
G
D
V
A
T
G
L
Site 39
T702
Q
E
L
F
G
R
V
T
S
R
V
T
N
D
G
Site 40
S703
E
L
F
G
R
V
T
S
R
V
T
N
D
G
E
Site 41
T706
G
R
V
T
S
R
V
T
N
D
G
E
I
W
R
Site 42
Y715
D
G
E
I
W
R
L
Y
A
H
V
Y
G
N
G
Site 43
Y719
W
R
L
Y
A
H
V
Y
G
N
G
Q
S
E
K
Site 44
S775
A
H
V
A
I
K
C
S
K
N
K
S
S
S
Q
Site 45
S779
I
K
C
S
K
N
K
S
S
S
Q
E
A
V
Q
Site 46
S781
C
S
K
N
K
S
S
S
Q
E
A
V
Q
M
L
Site 47
S790
E
A
V
Q
M
L
S
S
V
R
L
N
L
R
G
Site 48
T807
S
K
A
K
Q
L
F
T
D
V
A
T
G
E
M
Site 49
T827
D
D
I
T
A
M
D
T
L
V
T
E
L
Q
D
Site 50
S836
V
T
E
L
Q
D
L
S
N
Q
F
R
N
Q
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation