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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNNM4
Full Name:
Metal transporter CNNM4
Alias:
ACDP4; Ancient conserved domain-containing protein 4; Cyclin-M4
Type:
Unknown function
Mass (Da):
86607
Number AA:
775
UniProt ID:
Q6P4Q7
International Prot ID:
IPI00418426
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0016020
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006811
GO:0051234
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
L
G
A
R
G
Q
G
S
P
Q
Q
G
T
I
V
Site 2
S57
R
L
A
S
C
N
K
S
C
G
T
N
P
D
G
Site 3
S82
N
L
R
L
Y
G
Y
S
L
G
N
I
S
S
N
Site 4
S88
Y
S
L
G
N
I
S
S
N
L
I
S
F
T
E
Site 5
S92
N
I
S
S
N
L
I
S
F
T
E
V
D
D
A
Site 6
T101
T
E
V
D
D
A
E
T
L
H
K
S
T
S
C
Site 7
S105
D
A
E
T
L
H
K
S
T
S
C
L
E
L
T
Site 8
S107
E
T
L
H
K
S
T
S
C
L
E
L
T
K
D
Site 9
T128
V
N
V
S
R
G
N
T
S
G
V
L
V
V
L
Site 10
T136
S
G
V
L
V
V
L
T
K
F
L
R
R
S
E
Site 11
S142
L
T
K
F
L
R
R
S
E
S
M
K
L
Y
A
Site 12
S144
K
F
L
R
R
S
E
S
M
K
L
Y
A
L
C
Site 13
Y148
R
S
E
S
M
K
L
Y
A
L
C
T
R
A
Q
Site 14
T164
D
G
P
W
L
K
W
T
D
K
D
S
L
L
F
Site 15
S168
L
K
W
T
D
K
D
S
L
L
F
M
V
E
E
Site 16
Y228
G
T
E
K
E
R
R
Y
A
R
K
I
E
P
I
Site 17
T334
F
L
G
Q
E
I
R
T
V
Y
N
R
E
K
L
Site 18
Y336
G
Q
E
I
R
T
V
Y
N
R
E
K
L
M
E
Site 19
Y351
M
L
K
V
T
E
P
Y
N
D
L
V
K
E
E
Site 20
T372
A
L
E
L
R
T
K
T
V
E
D
I
M
T
Q
Site 21
T396
D
A
I
L
D
F
N
T
M
S
E
I
M
E
S
Site 22
S403
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
Site 23
Y405
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
Site 24
T406
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
D
Site 25
S416
P
V
F
E
D
E
Q
S
N
I
V
D
I
L
Y
Site 26
T436
F
V
D
P
D
D
C
T
P
L
K
T
I
T
R
Site 27
T440
D
D
C
T
P
L
K
T
I
T
R
F
Y
N
H
Site 28
Y445
L
K
T
I
T
R
F
Y
N
H
P
V
H
F
V
Site 29
S470
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
K
Site 30
Y488
E
G
E
G
D
P
F
Y
E
V
L
G
L
V
T
Site 31
S506
V
I
E
E
I
I
K
S
E
I
L
D
E
S
D
Site 32
S512
K
S
E
I
L
D
E
S
D
M
Y
T
D
N
R
Site 33
Y515
I
L
D
E
S
D
M
Y
T
D
N
R
S
R
K
Site 34
T516
L
D
E
S
D
M
Y
T
D
N
R
S
R
K
R
Site 35
S520
D
M
Y
T
D
N
R
S
R
K
R
V
S
E
K
Site 36
S525
N
R
S
R
K
R
V
S
E
K
N
K
R
D
F
Site 37
S533
E
K
N
K
R
D
F
S
A
F
K
D
A
D
N
Site 38
S566
A
T
E
V
S
Q
F
S
P
S
L
I
S
E
K
Site 39
S571
Q
F
S
P
S
L
I
S
E
K
I
L
L
R
L
Site 40
Y596
F
D
E
H
N
K
Y
Y
A
R
H
Y
L
Y
T
Site 41
Y597
T
P
L
S
R
S
A
S
L
S
Y
P
D
R
T
Site 42
Y601
N
K
Y
Y
A
R
H
Y
L
Y
T
R
N
K
P
Site 43
Y603
Y
Y
A
R
H
Y
L
Y
T
R
N
K
P
A
D
Site 44
T604
Y
A
R
H
Y
L
Y
T
R
N
K
P
A
D
Y
Site 45
Y611
T
R
N
K
P
A
D
Y
F
I
L
I
L
Q
G
Site 46
T633
K
E
N
M
K
F
E
T
G
A
F
S
Y
Y
G
Site 47
Y639
E
T
G
A
F
S
Y
Y
G
T
M
A
L
T
S
Site 48
T645
Y
Y
G
T
M
A
L
T
S
V
P
S
D
R
S
Site 49
S646
Y
G
T
M
A
L
T
S
V
P
S
D
R
S
P
Site 50
S649
M
A
L
T
S
V
P
S
D
R
S
P
A
H
P
Site 51
S652
T
S
V
P
S
D
R
S
P
A
H
P
T
P
L
Site 52
T657
D
R
S
P
A
H
P
T
P
L
S
R
S
A
S
Site 53
S660
P
A
H
P
T
P
L
S
R
S
A
S
L
S
Y
Site 54
S662
H
P
T
P
L
S
R
S
A
S
L
S
Y
P
D
Site 55
S664
K
F
D
E
H
N
K
Y
Y
A
R
H
Y
L
Y
Site 56
S666
L
S
R
S
A
S
L
S
Y
P
D
R
T
D
V
Site 57
Y667
S
R
S
A
S
L
S
Y
P
D
R
T
D
V
S
Site 58
T671
S
L
S
Y
P
D
R
T
D
V
S
T
A
A
T
Site 59
S674
Y
P
D
R
T
D
V
S
T
A
A
T
L
A
G
Site 60
T675
P
D
R
T
D
V
S
T
A
A
T
L
A
G
S
Site 61
T678
T
D
V
S
T
A
A
T
L
A
G
S
S
N
Q
Site 62
S682
T
A
A
T
L
A
G
S
S
N
Q
F
G
S
S
Site 63
S689
S
S
N
Q
F
G
S
S
V
L
G
Q
Y
I
S
Site 64
Y694
G
S
S
V
L
G
Q
Y
I
S
D
F
S
V
R
Site 65
Y708
R
A
L
V
D
L
Q
Y
I
K
I
T
R
Q
Q
Site 66
Y716
I
K
I
T
R
Q
Q
Y
Q
N
G
L
L
A
S
Site 67
S728
L
A
S
R
M
E
N
S
P
Q
F
P
I
D
G
Site 68
S747
M
E
N
L
A
E
K
S
E
L
P
V
V
D
E
Site 69
S764
T
L
L
N
E
R
N
S
L
L
H
K
A
S
H
Site 70
S770
N
S
L
L
H
K
A
S
H
E
N
A
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation