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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM171B
Full Name:
Protein FAM171B
Alias:
family with sequence similarity 171, member B; FLJ34104; K1946
Type:
Mass (Da):
92437
Number AA:
828
UniProt ID:
Q6P995
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T386
Y
C
R
D
K
C
G
T
P
Q
K
R
E
R
N
Site 2
T395
Q
K
R
E
R
N
I
T
K
L
E
V
L
K
R
Site 3
T405
E
V
L
K
R
D
Q
T
T
S
T
T
H
I
N
Site 4
S407
L
K
R
D
Q
T
T
S
T
T
H
I
N
H
I
Site 5
T416
T
H
I
N
H
I
S
T
V
K
V
A
L
K
A
Site 6
S427
A
L
K
A
E
D
K
S
Q
L
F
N
A
K
N
Site 7
S436
L
F
N
A
K
N
S
S
Y
S
P
Q
K
K
E
Site 8
S438
N
A
K
N
S
S
Y
S
P
Q
K
K
E
P
S
Site 9
S445
S
P
Q
K
K
E
P
S
K
A
E
T
E
E
R
Site 10
T449
K
E
P
S
K
A
E
T
E
E
R
V
S
M
V
Site 11
S454
A
E
T
E
E
R
V
S
M
V
K
T
R
D
D
Site 12
T458
E
R
V
S
M
V
K
T
R
D
D
F
K
I
Y
Site 13
Y465
T
R
D
D
F
K
I
Y
N
E
D
V
S
F
L
Site 14
S470
K
I
Y
N
E
D
V
S
F
L
S
V
N
Q
N
Site 15
S473
N
E
D
V
S
F
L
S
V
N
Q
N
N
Y
S
Site 16
Y479
L
S
V
N
Q
N
N
Y
S
R
N
P
T
Q
S
Site 17
S480
S
V
N
Q
N
N
Y
S
R
N
P
T
Q
S
L
Site 18
T484
N
N
Y
S
R
N
P
T
Q
S
L
E
P
N
V
Site 19
S486
Y
S
R
N
P
T
Q
S
L
E
P
N
V
G
S
Site 20
S504
K
H
I
N
N
N
L
S
S
S
L
G
D
A
Q
Site 21
S506
I
N
N
N
L
S
S
S
L
G
D
A
Q
D
E
Site 22
T518
Q
D
E
K
R
Y
L
T
G
N
E
E
A
Y
G
Site 23
Y524
L
T
G
N
E
E
A
Y
G
R
S
H
I
P
E
Site 24
S551
L
Q
T
S
D
L
F
S
T
P
E
Q
L
H
T
Site 25
T552
Q
T
S
D
L
F
S
T
P
E
Q
L
H
T
A
Site 26
T558
S
T
P
E
Q
L
H
T
A
K
S
A
T
L
P
Site 27
S561
E
Q
L
H
T
A
K
S
A
T
L
P
R
K
G
Site 28
T563
L
H
T
A
K
S
A
T
L
P
R
K
G
Q
L
Site 29
T587
N
R
E
N
F
T
Q
T
L
P
K
M
P
I
H
Site 30
S595
L
P
K
M
P
I
H
S
H
A
Q
P
P
D
A
Site 31
S614
I
I
L
E
G
Q
Q
S
L
P
S
Q
A
S
D
Site 32
S617
E
G
Q
Q
S
L
P
S
Q
A
S
D
W
S
R
Site 33
S620
Q
S
L
P
S
Q
A
S
D
W
S
R
Y
S
S
Site 34
S623
P
S
Q
A
S
D
W
S
R
Y
S
S
S
L
L
Site 35
S626
A
S
D
W
S
R
Y
S
S
S
L
L
E
S
V
Site 36
S627
S
D
W
S
R
Y
S
S
S
L
L
E
S
V
S
Site 37
S628
D
W
S
R
Y
S
S
S
L
L
E
S
V
S
V
Site 38
S634
S
S
L
L
E
S
V
S
V
P
G
T
L
N
E
Site 39
S656
S
S
E
L
Q
G
I
S
E
Q
T
L
L
E
L
Site 40
S664
E
Q
T
L
L
E
L
S
K
G
K
P
S
P
H
Site 41
S669
E
L
S
K
G
K
P
S
P
H
P
R
A
W
F
Site 42
S678
H
P
R
A
W
F
V
S
L
D
G
K
P
V
A
Site 43
S690
P
V
A
Q
V
R
H
S
F
I
D
L
K
K
G
Site 44
S702
K
K
G
K
R
T
Q
S
N
D
T
S
L
D
S
Site 45
T705
K
R
T
Q
S
N
D
T
S
L
D
S
G
V
D
Site 46
S706
R
T
Q
S
N
D
T
S
L
D
S
G
V
D
M
Site 47
S709
S
N
D
T
S
L
D
S
G
V
D
M
N
E
L
Site 48
S718
V
D
M
N
E
L
H
S
S
R
K
L
E
R
E
Site 49
S719
D
M
N
E
L
H
S
S
R
K
L
E
R
E
K
Site 50
T727
R
K
L
E
R
E
K
T
F
I
K
S
M
H
Q
Site 51
S731
R
E
K
T
F
I
K
S
M
H
Q
P
K
I
L
Site 52
Y739
M
H
Q
P
K
I
L
Y
L
E
D
L
D
L
S
Site 53
S746
Y
L
E
D
L
D
L
S
S
S
E
S
G
T
T
Site 54
S747
L
E
D
L
D
L
S
S
S
E
S
G
T
T
V
Site 55
S748
E
D
L
D
L
S
S
S
E
S
G
T
T
V
C
Site 56
S750
L
D
L
S
S
S
E
S
G
T
T
V
C
S
P
Site 57
T752
L
S
S
S
E
S
G
T
T
V
C
S
P
E
D
Site 58
T753
S
S
S
E
S
G
T
T
V
C
S
P
E
D
P
Site 59
S756
E
S
G
T
T
V
C
S
P
E
D
P
A
L
R
Site 60
S770
R
H
I
L
D
G
G
S
G
V
I
M
E
H
P
Site 61
S781
M
E
H
P
G
E
E
S
P
G
R
K
S
T
V
Site 62
S786
E
E
S
P
G
R
K
S
T
V
E
D
F
E
A
Site 63
T787
E
S
P
G
R
K
S
T
V
E
D
F
E
A
N
Site 64
T795
V
E
D
F
E
A
N
T
S
P
T
K
R
R
G
Site 65
S796
E
D
F
E
A
N
T
S
P
T
K
R
R
G
R
Site 66
S811
P
P
L
A
K
R
D
S
K
T
N
I
W
K
K
Site 67
T813
L
A
K
R
D
S
K
T
N
I
W
K
K
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation