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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PDXDC1
Full Name:
Pyridoxal-dependent decarboxylase domain-containing protein 1
Alias:
KIAA0251; LP8165; PDXD1; Pyridoxal-dependent decarboxylase domain containing 1
Type:
EC 4.1.1.-; Lyase
Mass (Da):
86707
Number AA:
788
UniProt ID:
Q6P996
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0016831
GO:0005515
GO:0030170
PhosphoSite+
KinaseNET
Biological Process:
GO:0019752
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
L
E
K
I
A
D
P
T
L
A
E
M
G
K
N
Site 2
S30
A
V
K
M
L
E
D
S
Q
R
R
T
E
E
E
Site 3
T34
L
E
D
S
Q
R
R
T
E
E
E
N
G
K
K
Site 4
S79
D
E
D
E
E
P
Q
S
P
R
I
Q
N
I
G
Site 5
Y101
L
G
H
S
L
G
A
Y
I
S
T
L
D
K
E
Site 6
S103
H
S
L
G
A
Y
I
S
T
L
D
K
E
K
L
Site 7
T114
K
E
K
L
R
K
L
T
T
R
I
L
S
D
T
Site 8
T115
E
K
L
R
K
L
T
T
R
I
L
S
D
T
T
Site 9
Y137
R
Y
E
N
G
C
A
Y
F
H
E
E
E
R
E
Site 10
S156
I
C
R
L
A
I
H
S
R
Y
E
D
F
V
V
Site 11
Y189
A
R
P
G
L
G
Q
Y
L
C
N
Q
L
G
L
Site 12
S212
P
C
N
T
V
F
G
S
Q
H
Q
M
D
V
A
Site 13
T296
A
A
K
C
D
S
M
T
M
T
P
G
P
W
L
Site 14
T298
K
C
D
S
M
T
M
T
P
G
P
W
L
G
L
Site 15
T322
K
H
D
D
P
A
L
T
L
V
A
G
L
T
S
Site 16
S364
I
K
H
A
C
Q
L
S
Q
R
L
Q
E
S
L
Site 17
S370
L
S
Q
R
L
Q
E
S
L
K
K
V
N
Y
I
Site 18
Y376
E
S
L
K
K
V
N
Y
I
K
I
L
V
E
D
Site 19
T414
A
V
P
V
P
N
M
T
P
S
G
V
G
R
E
Site 20
S416
P
V
P
N
M
T
P
S
G
V
G
R
E
R
H
Site 21
S424
G
V
G
R
E
R
H
S
C
D
A
L
N
R
W
Site 22
T470
M
T
A
A
V
L
G
T
R
G
E
D
V
D
Q
Site 23
Y511
E
A
T
A
G
L
L
Y
V
D
D
P
N
W
S
Site 24
Y525
S
G
I
G
V
V
R
Y
E
H
A
N
D
D
K
Site 25
S533
E
H
A
N
D
D
K
S
S
L
K
S
D
P
E
Site 26
S534
H
A
N
D
D
K
S
S
L
K
S
D
P
E
G
Site 27
S537
D
D
K
S
S
L
K
S
D
P
E
G
E
N
I
Site 28
S557
K
K
L
N
E
L
E
S
D
L
T
F
K
I
G
Site 29
T560
N
E
L
E
S
D
L
T
F
K
I
G
P
E
Y
Site 30
Y567
T
F
K
I
G
P
E
Y
K
S
M
K
S
C
L
Site 31
S569
K
I
G
P
E
Y
K
S
M
K
S
C
L
Y
V
Site 32
Y575
K
S
M
K
S
C
L
Y
V
G
M
A
S
D
N
Site 33
T610
S
R
L
L
E
N
M
T
E
V
V
R
K
G
I
Site 34
S652
G
S
V
L
N
W
F
S
P
V
Q
A
L
Q
K
Site 35
T662
Q
A
L
Q
K
G
R
T
F
N
L
T
A
G
S
Site 36
T666
K
G
R
T
F
N
L
T
A
G
S
L
E
S
T
Site 37
S669
T
F
N
L
T
A
G
S
L
E
S
T
E
P
I
Site 38
T673
T
A
G
S
L
E
S
T
E
P
I
Y
V
Y
K
Site 39
Y677
L
E
S
T
E
P
I
Y
V
Y
K
A
Q
G
A
Site 40
Y679
S
T
E
P
I
Y
V
Y
K
A
Q
G
A
G
V
Site 41
T687
K
A
Q
G
A
G
V
T
L
P
P
T
P
S
G
Site 42
T691
A
G
V
T
L
P
P
T
P
S
G
S
R
T
K
Site 43
S693
V
T
L
P
P
T
P
S
G
S
R
T
K
Q
R
Site 44
S695
L
P
P
T
P
S
G
S
R
T
K
Q
R
L
P
Site 45
T697
P
T
P
S
G
S
R
T
K
Q
R
L
P
G
Q
Site 46
S710
G
Q
K
P
F
K
R
S
L
R
G
S
D
A
L
Site 47
S714
F
K
R
S
L
R
G
S
D
A
L
S
E
T
S
Site 48
S718
L
R
G
S
D
A
L
S
E
T
S
S
V
S
H
Site 49
T720
G
S
D
A
L
S
E
T
S
S
V
S
H
I
E
Site 50
S721
S
D
A
L
S
E
T
S
S
V
S
H
I
E
D
Site 51
S722
D
A
L
S
E
T
S
S
V
S
H
I
E
D
L
Site 52
S724
L
S
E
T
S
S
V
S
H
I
E
D
L
E
K
Site 53
S736
L
E
K
V
E
R
L
S
S
G
P
E
Q
I
T
Site 54
S737
E
K
V
E
R
L
S
S
G
P
E
Q
I
T
L
Site 55
T743
S
S
G
P
E
Q
I
T
L
E
A
S
S
T
E
Site 56
S748
Q
I
T
L
E
A
S
S
T
E
G
H
P
G
A
Site 57
T749
I
T
L
E
A
S
S
T
E
G
H
P
G
A
P
Site 58
S757
E
G
H
P
G
A
P
S
P
Q
H
T
D
Q
T
Site 59
T761
G
A
P
S
P
Q
H
T
D
Q
T
E
A
F
Q
Site 60
T764
S
P
Q
H
T
D
Q
T
E
A
F
Q
K
G
V
Site 61
S779
P
H
P
E
D
D
H
S
Q
V
E
G
P
E
S
Site 62
S786
S
Q
V
E
G
P
E
S
L
R
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation