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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INTS5
Full Name:
Integrator complex subunit 5
Alias:
Int5; KIAA1698
Type:
RNA processing
Mass (Da):
107995
Number AA:
1019
UniProt ID:
Q6P9B9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0032039
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016180
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
P
P
G
P
A
P
A
T
H
G
P
A
P
L
S
Site 2
S27
T
H
G
P
A
P
L
S
A
Q
E
L
S
Q
E
Site 3
S32
P
L
S
A
Q
E
L
S
Q
E
I
K
A
F
L
Site 4
S51
P
I
L
G
H
Q
L
S
A
R
E
H
A
R
C
Site 5
T95
H
L
A
A
L
D
E
T
P
V
A
G
P
P
H
Site 6
S109
H
L
R
P
P
P
P
S
H
V
P
A
G
G
P
Site 7
S156
I
D
L
M
G
Q
L
S
S
T
Y
S
G
Q
H
Site 8
S157
D
L
M
G
Q
L
S
S
T
Y
S
G
Q
H
Q
Site 9
T158
L
M
G
Q
L
S
S
T
Y
S
G
Q
H
Q
R
Site 10
Y159
M
G
Q
L
S
S
T
Y
S
G
Q
H
Q
R
V
Site 11
S160
G
Q
L
S
S
T
Y
S
G
Q
H
Q
R
V
P
Site 12
T215
C
V
D
A
L
L
D
T
S
V
Q
H
S
P
H
Site 13
S216
V
D
A
L
L
D
T
S
V
Q
H
S
P
H
F
Site 14
S220
L
D
T
S
V
Q
H
S
P
H
F
D
W
V
V
Site 15
S262
G
A
G
G
G
A
G
S
S
G
G
S
S
S
Q
Site 16
S263
A
G
G
G
A
G
S
S
G
G
S
S
S
Q
T
Site 17
S266
G
A
G
S
S
G
G
S
S
S
Q
T
P
S
T
Site 18
S267
A
G
S
S
G
G
S
S
S
Q
T
P
S
T
D
Site 19
S268
G
S
S
G
G
S
S
S
Q
T
P
S
T
D
P
Site 20
T270
S
G
G
S
S
S
Q
T
P
S
T
D
P
F
P
Site 21
S272
G
S
S
S
Q
T
P
S
T
D
P
F
P
G
S
Site 22
T273
S
S
S
Q
T
P
S
T
D
P
F
P
G
S
P
Site 23
S279
S
T
D
P
F
P
G
S
P
A
I
P
A
E
K
Site 24
S303
G
I
L
G
H
L
A
S
R
H
G
D
S
I
R
Site 25
S308
L
A
S
R
H
G
D
S
I
R
R
E
L
L
R
Site 26
S325
H
D
S
L
A
G
G
S
G
G
R
S
G
D
P
Site 27
S329
A
G
G
S
G
G
R
S
G
D
P
S
L
Q
A
Site 28
S333
G
G
R
S
G
D
P
S
L
Q
A
T
V
P
F
Site 29
S370
L
K
P
P
A
V
L
S
Q
L
Q
Q
H
L
Q
Site 30
T430
Q
G
L
A
V
P
D
T
V
R
E
A
C
D
R
Site 31
S456
L
V
H
H
R
G
G
S
P
G
E
G
V
L
G
Site 32
S513
L
S
V
Y
T
R
P
S
C
G
P
E
A
L
G
Site 33
S524
E
A
L
G
H
L
L
S
R
A
R
S
P
E
E
Site 34
S528
H
L
L
S
R
A
R
S
P
E
E
L
S
L
A
Site 35
S533
A
R
S
P
E
E
L
S
L
A
T
Q
L
Y
A
Site 36
T571
G
T
L
Q
P
P
F
T
A
R
F
L
R
N
L
Site 37
S602
L
G
A
H
F
G
E
S
A
S
A
H
L
S
D
Site 38
S658
G
V
H
R
F
F
A
S
L
R
L
H
G
P
P
Site 39
S669
H
G
P
P
G
V
A
S
A
C
Q
L
L
T
R
Site 40
T702
G
A
L
H
R
G
N
T
E
L
F
G
G
Q
V
Site 41
T715
Q
V
D
G
D
N
E
T
L
S
V
V
S
A
S
Site 42
S717
D
G
D
N
E
T
L
S
V
V
S
A
S
L
A
Site 43
S727
S
A
S
L
A
S
A
S
L
L
D
T
N
R
R
Site 44
T731
A
S
A
S
L
L
D
T
N
R
R
H
T
A
A
Site 45
T736
L
D
T
N
R
R
H
T
A
A
V
P
G
P
G
Site 46
Y774
R
N
Q
Q
E
V
I
Y
N
T
Q
S
L
L
S
Site 47
T840
P
E
E
H
A
R
A
T
V
E
R
D
L
R
I
Site 48
T897
E
A
S
R
H
P
D
T
T
H
S
P
W
H
L
Site 49
T898
A
S
R
H
P
D
T
T
H
S
P
W
H
L
E
Site 50
S900
R
H
P
D
T
T
H
S
P
W
H
L
E
A
S
Site 51
S964
P
Q
K
F
I
F
Q
S
E
R
G
R
F
I
R
Site 52
S974
G
R
F
I
R
D
F
S
R
E
G
G
G
E
G
Site 53
S1003
I
D
R
L
G
L
F
S
G
R
F
Q
A
P
S
Site 54
S1010
S
G
R
F
Q
A
P
S
P
S
T
L
L
R
Q
Site 55
S1012
R
F
Q
A
P
S
P
S
T
L
L
R
Q
G
T
Site 56
T1013
F
Q
A
P
S
P
S
T
L
L
R
Q
G
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation