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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PGM2L1
Full Name:
Glucose 1,6-bisphosphate synthase
Alias:
BM32A; EC 5.4.2.2; Phosphoglucomutase-2-like 1; PMMLP
Type:
Enzyme - Isomerase
Mass (Da):
70456
Number AA:
622
UniProt ID:
Q6PCE3
International Prot ID:
IPI00173346
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0047933
GO:0016868
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0006006
GO:0005996
GO:0006006
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
S
N
L
L
H
A
P
Y
H
T
G
D
P
Q
L
Site 2
T27
T
G
D
P
Q
L
D
T
A
I
G
Q
W
L
R
Site 3
T41
R
W
D
K
N
P
K
T
K
E
Q
I
E
N
L
Site 4
T66
D
R
L
C
C
R
M
T
F
G
T
A
G
L
R
Site 5
Y98
S
T
Q
G
M
Y
K
Y
L
E
R
C
F
S
D
Site 6
S104
K
Y
L
E
R
C
F
S
D
F
K
Q
R
G
F
Site 7
Y115
Q
R
G
F
V
V
G
Y
D
T
R
G
Q
V
T
Site 8
T117
G
F
V
V
G
Y
D
T
R
G
Q
V
T
S
S
Site 9
T122
Y
D
T
R
G
Q
V
T
S
S
C
S
S
Q
R
Site 10
S123
D
T
R
G
Q
V
T
S
S
C
S
S
Q
R
L
Site 11
S124
T
R
G
Q
V
T
S
S
C
S
S
Q
R
L
A
Site 12
S127
Q
V
T
S
S
C
S
S
Q
R
L
A
K
L
T
Site 13
T134
S
Q
R
L
A
K
L
T
A
A
V
L
L
A
K
Site 14
Y159
V
P
T
P
F
V
P
Y
A
V
Q
K
L
K
A
Site 15
T173
A
V
A
G
V
M
I
T
A
S
H
N
R
K
E
Site 16
S175
A
G
V
M
I
T
A
S
H
N
R
K
E
D
N
Site 17
Y184
N
R
K
E
D
N
G
Y
K
V
Y
W
E
T
G
Site 18
Y187
E
D
N
G
Y
K
V
Y
W
E
T
G
A
Q
I
Site 19
S196
E
T
G
A
Q
I
T
S
P
H
D
K
E
I
L
Site 20
S225
N
D
N
L
V
D
T
S
P
L
K
R
D
P
L
Site 21
Y239
L
Q
D
I
C
R
R
Y
M
E
D
L
K
K
I
Site 22
T256
Y
R
E
L
N
S
K
T
T
L
K
F
V
H
T
Site 23
S299
K
D
P
D
P
D
F
S
T
V
K
C
P
N
P
Site 24
T300
D
P
D
P
D
F
S
T
V
K
C
P
N
P
E
Site 25
S311
P
N
P
E
E
G
E
S
V
L
E
L
S
L
R
Site 26
S316
G
E
S
V
L
E
L
S
L
R
L
A
E
K
E
Site 27
T331
N
A
R
V
V
L
A
T
D
P
D
A
D
R
L
Site 28
T466
E
M
A
S
Y
L
E
T
M
N
I
T
L
K
Q
Site 29
Y479
K
Q
Q
L
V
K
V
Y
E
K
Y
G
Y
H
I
Site 30
Y482
L
V
K
V
Y
E
K
Y
G
Y
H
I
S
K
T
Site 31
Y484
K
V
Y
E
K
Y
G
Y
H
I
S
K
T
S
Y
Site 32
Y491
Y
H
I
S
K
T
S
Y
F
L
C
Y
E
P
P
Site 33
Y495
K
T
S
Y
F
L
C
Y
E
P
P
T
I
K
S
Site 34
S512
E
R
L
R
N
F
D
S
P
K
E
Y
P
K
F
Site 35
Y516
N
F
D
S
P
K
E
Y
P
K
F
C
G
T
F
Site 36
T532
I
L
H
V
R
D
I
T
T
G
Y
D
S
S
Q
Site 37
T533
L
H
V
R
D
I
T
T
G
Y
D
S
S
Q
P
Site 38
Y535
V
R
D
I
T
T
G
Y
D
S
S
Q
P
N
K
Site 39
S538
I
T
T
G
Y
D
S
S
Q
P
N
K
K
S
V
Site 40
S544
S
S
Q
P
N
K
K
S
V
L
P
V
S
K
N
Site 41
S549
K
K
S
V
L
P
V
S
K
N
S
Q
M
I
T
Site 42
T556
S
K
N
S
Q
M
I
T
F
T
F
Q
N
G
C
Site 43
T566
F
Q
N
G
C
V
A
T
L
R
T
S
G
T
E
Site 44
S570
C
V
A
T
L
R
T
S
G
T
E
P
K
I
K
Site 45
T572
A
T
L
R
T
S
G
T
E
P
K
I
K
Y
Y
Site 46
Y578
G
T
E
P
K
I
K
Y
Y
A
E
M
C
A
S
Site 47
Y579
T
E
P
K
I
K
Y
Y
A
E
M
C
A
S
P
Site 48
S585
Y
Y
A
E
M
C
A
S
P
D
Q
S
D
T
A
Site 49
S589
M
C
A
S
P
D
Q
S
D
T
A
L
L
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation