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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL19
Full Name:
F-box/LRR-repeat protein 19
Alias:
DKFZp434K0410; FBL19; F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19: F-box and leucine-rich repeat protein 19: F-box/LRR-repeat protein 19: F-box and leucine-rich repeat protein 19; FXL19; JHDM1C; Jumonji C domain-containing histone demethylase 1C
Type:
Unknown function
Mass (Da):
73771
Number AA:
674
UniProt ID:
Q6PCT2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
S
S
S
R
G
P
G
A
G
A
Site 2
T17
A
G
A
R
R
R
R
T
R
C
R
R
C
R
A
Site 3
T79
G
E
A
G
K
E
D
T
V
E
G
E
E
E
K
Site 4
T95
G
L
S
L
M
E
C
T
I
C
N
E
I
V
H
Site 5
S135
C
T
Q
E
G
R
T
S
K
D
S
G
E
G
P
Site 6
S138
E
G
R
T
S
K
D
S
G
E
G
P
G
R
R
Site 7
S155
D
N
G
E
E
G
A
S
L
G
S
G
W
K
L
Site 8
T163
L
G
S
G
W
K
L
T
E
E
P
P
L
P
P
Site 9
T205
E
A
G
N
E
P
P
T
P
R
K
K
V
K
G
Site 10
S231
D
A
C
L
L
R
G
S
D
P
G
G
P
G
L
Site 11
S247
P
P
R
V
L
N
P
S
Q
A
F
S
S
C
H
Site 12
S251
L
N
P
S
Q
A
F
S
S
C
H
P
G
L
P
Site 13
S252
N
P
S
Q
A
F
S
S
C
H
P
G
L
P
P
Site 14
S279
A
E
G
P
A
V
P
S
P
S
P
Q
R
E
K
Site 15
S281
G
P
A
V
P
S
P
S
P
Q
R
E
K
L
E
Site 16
T303
L
L
E
R
V
P
D
T
S
S
S
S
S
D
S
Site 17
S304
L
E
R
V
P
D
T
S
S
S
S
S
D
S
D
Site 18
S305
E
R
V
P
D
T
S
S
S
S
S
D
S
D
S
Site 19
S306
R
V
P
D
T
S
S
S
S
S
D
S
D
S
D
Site 20
S307
V
P
D
T
S
S
S
S
S
D
S
D
S
D
S
Site 21
S308
P
D
T
S
S
S
S
S
D
S
D
S
D
S
D
Site 22
S310
T
S
S
S
S
S
D
S
D
S
D
S
D
S
S
Site 23
S312
S
S
S
S
D
S
D
S
D
S
D
S
S
G
T
Site 24
S314
S
S
D
S
D
S
D
S
D
S
S
G
T
S
L
Site 25
S316
D
S
D
S
D
S
D
S
S
G
T
S
L
S
E
Site 26
S317
S
D
S
D
S
D
S
S
G
T
S
L
S
E
D
Site 27
S320
D
S
D
S
S
G
T
S
L
S
E
D
E
A
P
Site 28
S322
D
S
S
G
T
S
L
S
E
D
E
A
P
G
E
Site 29
S340
G
R
R
P
A
R
G
S
S
G
E
K
E
N
R
Site 30
S341
R
R
P
A
R
G
S
S
G
E
K
E
N
R
G
Site 31
S357
R
R
A
V
R
P
G
S
G
G
P
L
L
S
W
Site 32
S388
V
V
R
P
P
P
R
S
P
E
P
D
T
L
P
Site 33
T393
P
R
S
P
E
P
D
T
L
P
L
A
A
G
S
Site 34
S400
T
L
P
L
A
A
G
S
D
H
P
L
P
R
A
Site 35
S447
L
W
P
R
M
D
L
S
R
R
K
S
L
T
P
Site 36
S451
M
D
L
S
R
R
K
S
L
T
P
P
M
L
S
Site 37
T453
L
S
R
R
K
S
L
T
P
P
M
L
S
G
V
Site 38
S458
S
L
T
P
P
M
L
S
G
V
V
R
R
Q
P
Site 39
S471
Q
P
R
A
L
D
L
S
W
T
G
V
S
K
K
Site 40
S528
W
I
E
D
V
K
D
S
Q
L
R
E
L
L
L
Site 41
T540
L
L
L
P
P
P
D
T
K
P
G
Q
T
E
S
Site 42
S547
T
K
P
G
Q
T
E
S
R
G
R
L
Q
G
V
Site 43
T565
R
L
A
G
L
E
L
T
D
A
S
L
R
L
L
Site 44
S580
L
R
H
A
P
Q
L
S
A
L
D
L
S
H
C
Site 45
T599
D
P
S
V
H
L
L
T
A
P
T
S
P
L
R
Site 46
T608
P
T
S
P
L
R
E
T
L
V
H
L
N
L
A
Site 47
S641
L
R
R
L
D
L
R
S
C
R
Q
L
S
P
E
Site 48
S646
L
R
S
C
R
Q
L
S
P
E
A
C
A
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation