KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KLKBL4
Full Name:
Inactive serine protease 54
Alias:
Cancer/testis antigen 67;Plasma kallikrein-like protein 4
Type:
Mass (Da):
43832
Number AA:
395
UniProt ID:
Q6PEW0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
G
L
L
Y
S
S
T
S
C
G
V
Q
K
A
S
Site 2
S36
S
C
G
V
Q
K
A
S
V
F
Y
G
P
D
P
Site 3
S49
D
P
K
E
G
L
V
S
S
M
E
F
P
W
V
Site 4
Y64
V
S
L
Q
D
S
Q
Y
T
H
L
A
F
G
C
Site 5
S103
G
I
S
N
M
D
P
S
K
I
A
H
T
E
Y
Site 6
S127
D
F
D
N
N
S
M
S
N
N
I
A
L
L
K
Site 7
Y198
D
L
D
M
C
P
L
Y
K
L
Q
K
T
E
C
Site 8
T203
P
L
Y
K
L
Q
K
T
E
C
G
S
H
T
K
Site 9
T215
H
T
K
E
E
T
K
T
A
C
L
G
D
P
G
Site 10
Y254
T
C
P
G
L
F
L
Y
T
K
V
E
D
Y
S
Site 11
Y260
L
Y
T
K
V
E
D
Y
S
K
W
I
T
S
K
Site 12
T265
E
D
Y
S
K
W
I
T
S
K
A
E
R
A
G
Site 13
S276
E
R
A
G
P
P
L
S
S
L
H
H
W
E
K
Site 14
T295
S
H
H
G
P
N
A
T
M
T
Q
K
T
Y
S
Site 15
T297
H
G
P
N
A
T
M
T
Q
K
T
Y
S
D
S
Site 16
T300
N
A
T
M
T
Q
K
T
Y
S
D
S
E
L
G
Site 17
S302
T
M
T
Q
K
T
Y
S
D
S
E
L
G
H
V
Site 18
S304
T
Q
K
T
Y
S
D
S
E
L
G
H
V
G
S
Site 19
S311
S
E
L
G
H
V
G
S
Y
L
Q
G
Q
R
R
Site 20
T319
Y
L
Q
G
Q
R
R
T
I
T
H
S
R
L
G
Site 21
T321
Q
G
Q
R
R
T
I
T
H
S
R
L
G
N
S
Site 22
S323
Q
R
R
T
I
T
H
S
R
L
G
N
S
S
R
Site 23
S328
T
H
S
R
L
G
N
S
S
R
D
S
L
D
V
Site 24
S329
H
S
R
L
G
N
S
S
R
D
S
L
D
V
R
Site 25
S332
L
G
N
S
S
R
D
S
L
D
V
R
E
K
D
Site 26
S343
R
E
K
D
V
K
E
S
G
R
S
P
E
A
S
Site 27
S346
D
V
K
E
S
G
R
S
P
E
A
S
V
Q
P
Site 28
S350
S
G
R
S
P
E
A
S
V
Q
P
L
Y
Y
D
Site 29
Y355
E
A
S
V
Q
P
L
Y
Y
D
Y
Y
G
G
E
Site 30
Y356
A
S
V
Q
P
L
Y
Y
D
Y
Y
G
G
E
V
Site 31
Y358
V
Q
P
L
Y
Y
D
Y
Y
G
G
E
V
G
E
Site 32
Y359
Q
P
L
Y
Y
D
Y
Y
G
G
E
V
G
E
G
Site 33
Y376
F
A
G
Q
N
R
L
Y
Q
P
E
E
I
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation