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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSRC1
Full Name:
Proline/serine-rich coiled-coil protein 1
Alias:
DDA3; differential display and activated by p53; FP3214; p53-regulated DDA3; proline/serine-rich coiled-coil 1
Type:
Tumor suppressor
Mass (Da):
38800
Number AA:
363
UniProt ID:
Q6PGN9
International Prot ID:
IPI00027963
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0030496
GO:0005819
Uniprot
OncoNet
Molecular Function:
GO:0008017
GO:0005515
GO:0008017
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0001578
GO:0030308
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
T
L
D
F
G
G
L
S
P
S
D
S
R
E
E
Site 2
S24
D
F
G
G
L
S
P
S
D
S
R
E
E
E
D
Site 3
S26
G
G
L
S
P
S
D
S
R
E
E
E
D
I
T
Site 4
T33
S
R
E
E
E
D
I
T
V
L
V
T
P
E
K
Site 5
T37
E
D
I
T
V
L
V
T
P
E
K
P
L
R
R
Site 6
S47
K
P
L
R
R
G
L
S
H
R
S
D
P
N
A
Site 7
S65
A
P
Q
G
V
R
L
S
L
G
P
L
S
P
E
Site 8
S70
R
L
S
L
G
P
L
S
P
E
K
L
E
E
I
Site 9
S98
C
A
L
Q
D
R
E
S
A
G
E
G
L
G
P
Site 10
S111
G
P
R
R
V
K
P
S
P
R
R
E
T
F
V
Site 11
T116
K
P
S
P
R
R
E
T
F
V
L
K
D
S
P
Site 12
S122
E
T
F
V
L
K
D
S
P
V
R
D
L
L
P
Site 13
T130
P
V
R
D
L
L
P
T
V
N
S
L
T
R
S
Site 14
S133
D
L
L
P
T
V
N
S
L
T
R
S
T
P
S
Site 15
T135
L
P
T
V
N
S
L
T
R
S
T
P
S
P
S
Site 16
S137
T
V
N
S
L
T
R
S
T
P
S
P
S
S
L
Site 17
T138
V
N
S
L
T
R
S
T
P
S
P
S
S
L
T
Site 18
S140
S
L
T
R
S
T
P
S
P
S
S
L
T
P
R
Site 19
S142
T
R
S
T
P
S
P
S
S
L
T
P
R
L
R
Site 20
S143
R
S
T
P
S
P
S
S
L
T
P
R
L
R
S
Site 21
T145
T
P
S
P
S
S
L
T
P
R
L
R
S
N
D
Site 22
S150
S
L
T
P
R
L
R
S
N
D
R
K
G
S
V
Site 23
S156
R
S
N
D
R
K
G
S
V
R
A
L
R
A
T
Site 24
T163
S
V
R
A
L
R
A
T
S
G
K
R
P
S
N
Site 25
S164
V
R
A
L
R
A
T
S
G
K
R
P
S
N
M
Site 26
S169
A
T
S
G
K
R
P
S
N
M
K
R
E
S
P
Site 27
S175
P
S
N
M
K
R
E
S
P
T
C
N
L
F
P
Site 28
T177
N
M
K
R
E
S
P
T
C
N
L
F
P
A
S
Site 29
S184
T
C
N
L
F
P
A
S
K
S
P
A
S
S
P
Site 30
S186
N
L
F
P
A
S
K
S
P
A
S
S
P
L
T
Site 31
S189
P
A
S
K
S
P
A
S
S
P
L
T
R
S
T
Site 32
S190
A
S
K
S
P
A
S
S
P
L
T
R
S
T
P
Site 33
T193
S
P
A
S
S
P
L
T
R
S
T
P
P
V
R
Site 34
S195
A
S
S
P
L
T
R
S
T
P
P
V
R
G
R
Site 35
T196
S
S
P
L
T
R
S
T
P
P
V
R
G
R
A
Site 36
S206
V
R
G
R
A
G
P
S
G
R
A
A
A
S
E
Site 37
S223
R
A
A
K
L
R
V
S
G
S
G
E
F
V
G
Site 38
S225
A
K
L
R
V
S
G
S
G
E
F
V
G
L
T
Site 39
S239
T
L
K
F
L
H
P
S
P
P
G
P
P
T
P
Site 40
T245
P
S
P
P
G
P
P
T
P
I
R
S
V
L
A
Site 41
S249
G
P
P
T
P
I
R
S
V
L
A
P
Q
P
S
Site 42
S256
S
V
L
A
P
Q
P
S
T
S
N
S
Q
R
L
Site 43
S258
L
A
P
Q
P
S
T
S
N
S
Q
R
L
P
R
Site 44
S260
P
Q
P
S
T
S
N
S
Q
R
L
P
R
P
Q
Site 45
S273
P
Q
G
A
A
A
K
S
S
S
Q
L
P
I
P
Site 46
S275
G
A
A
A
K
S
S
S
Q
L
P
I
P
S
A
Site 47
S281
S
S
Q
L
P
I
P
S
A
I
P
R
P
A
S
Site 48
S288
S
A
I
P
R
P
A
S
R
M
P
L
T
S
R
Site 49
T293
P
A
S
R
M
P
L
T
S
R
S
V
P
P
G
Site 50
S294
A
S
R
M
P
L
T
S
R
S
V
P
P
G
R
Site 51
S296
R
M
P
L
T
S
R
S
V
P
P
G
R
G
A
Site 52
S308
R
G
A
L
P
P
D
S
L
S
T
R
K
G
L
Site 53
S310
A
L
P
P
D
S
L
S
T
R
K
G
L
P
R
Site 54
T311
L
P
P
D
S
L
S
T
R
K
G
L
P
R
P
Site 55
S319
R
K
G
L
P
R
P
S
T
A
G
H
R
V
R
Site 56
T320
K
G
L
P
R
P
S
T
A
G
H
R
V
R
E
Site 57
S328
A
G
H
R
V
R
E
S
G
H
K
V
P
V
S
Site 58
S335
S
G
H
K
V
P
V
S
Q
R
L
N
L
P
V
Site 59
S348
P
V
M
G
A
T
R
S
N
L
Q
P
P
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation