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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBX38
Full Name:
F-box only protein 38
Alias:
F-box protein 38; Fbx38; FBXO38; FLJ13962; FX38; Modulator of KLF7 activity; Modulator of KLF7 activity homolog; MoKA; SP329
Type:
Ubiquitin conjugating system
Mass (Da):
133944
Number AA:
1188
UniProt ID:
Q6PIJ6
International Prot ID:
IPI00456676
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
T
A
D
E
T
K
D
Y
M
N
Q
L
S
H
E
Site 2
T65
R
K
L
K
E
A
V
T
L
Y
L
R
V
V
R
Site 3
Y108
M
P
D
V
E
Q
L
Y
G
L
H
P
R
Y
L
Site 4
Y114
L
Y
G
L
H
P
R
Y
L
E
R
R
R
V
R
Site 5
Y214
I
P
M
L
R
H
L
Y
M
K
W
V
R
L
T
Site 6
T221
Y
M
K
W
V
R
L
T
K
P
Q
P
F
K
D
Site 7
S286
I
Q
H
V
V
E
D
S
W
R
S
G
G
F
R
Site 8
T332
V
R
I
Q
P
S
L
T
K
D
G
V
F
S
A
Site 9
T427
I
S
D
H
S
R
W
T
R
L
V
D
I
N
L
Site 10
S490
G
V
S
S
A
L
V
S
N
Q
N
S
N
N
D
Site 11
S494
A
L
V
S
N
Q
N
S
N
N
D
D
N
N
A
Site 12
S519
N
H
H
H
P
D
D
S
D
E
E
N
D
F
R
Site 13
S558
D
G
E
V
V
A
E
S
G
N
N
T
P
A
H
Site 14
T562
V
A
E
S
G
N
N
T
P
A
H
S
Q
A
I
Site 15
S566
G
N
N
T
P
A
H
S
Q
A
I
I
P
V
D
Site 16
T591
L
Q
R
V
V
K
P
T
S
I
T
V
H
D
S
Site 17
S592
Q
R
V
V
K
P
T
S
I
T
V
H
D
S
E
Site 18
T594
V
V
K
P
T
S
I
T
V
H
D
S
E
S
D
Site 19
S598
T
S
I
T
V
H
D
S
E
S
D
D
E
E
D
Site 20
S600
I
T
V
H
D
S
E
S
D
D
E
E
D
S
L
Site 21
S606
E
S
D
D
E
E
D
S
L
E
L
Q
E
V
W
Site 22
T619
V
W
I
P
K
N
G
T
R
R
Y
S
E
R
E
Site 23
Y622
P
K
N
G
T
R
R
Y
S
E
R
E
E
K
T
Site 24
S623
K
N
G
T
R
R
Y
S
E
R
E
E
K
T
G
Site 25
S635
K
T
G
E
S
V
Q
S
R
E
L
S
V
S
G
Site 26
S639
S
V
Q
S
R
E
L
S
V
S
G
K
G
K
T
Site 27
S641
Q
S
R
E
L
S
V
S
G
K
G
K
T
P
L
Site 28
T646
S
V
S
G
K
G
K
T
P
L
R
K
R
Y
N
Site 29
Y652
K
T
P
L
R
K
R
Y
N
S
H
Q
M
G
Q
Site 30
S654
P
L
R
K
R
Y
N
S
H
Q
M
G
Q
S
K
Site 31
Y701
K
K
K
N
K
D
V
Y
P
S
C
S
S
T
T
Site 32
S703
K
N
K
D
V
Y
P
S
C
S
S
T
T
A
S
Site 33
S705
K
D
V
Y
P
S
C
S
S
T
T
A
S
T
V
Site 34
S706
D
V
Y
P
S
C
S
S
T
T
A
S
T
V
G
Site 35
T707
V
Y
P
S
C
S
S
T
T
A
S
T
V
G
N
Site 36
S710
S
C
S
S
T
T
A
S
T
V
G
N
S
S
S
Site 37
T711
C
S
S
T
T
A
S
T
V
G
N
S
S
S
H
Site 38
S717
S
T
V
G
N
S
S
S
H
N
T
A
S
Q
S
Site 39
T720
G
N
S
S
S
H
N
T
A
S
Q
S
P
D
F
Site 40
S722
S
S
S
H
N
T
A
S
Q
S
P
D
F
V
R
Site 41
S724
S
H
N
T
A
S
Q
S
P
D
F
V
R
T
V
Site 42
T730
Q
S
P
D
F
V
R
T
V
N
S
G
G
S
S
Site 43
S733
D
F
V
R
T
V
N
S
G
G
S
S
E
P
S
Site 44
S736
R
T
V
N
S
G
G
S
S
E
P
S
P
T
E
Site 45
S737
T
V
N
S
G
G
S
S
E
P
S
P
T
E
V
Site 46
S740
S
G
G
S
S
E
P
S
P
T
E
V
D
V
S
Site 47
T742
G
S
S
E
P
S
P
T
E
V
D
V
S
R
Q
Site 48
S747
S
P
T
E
V
D
V
S
R
Q
C
A
C
S
P
Site 49
S753
V
S
R
Q
C
A
C
S
P
G
G
S
E
D
S
Site 50
S757
C
A
C
S
P
G
G
S
E
D
S
E
A
M
E
Site 51
S760
S
P
G
G
S
E
D
S
E
A
M
E
E
G
D
Site 52
T788
P
Q
E
S
Q
R
R
T
S
R
C
S
D
E
E
Site 53
S789
Q
E
S
Q
R
R
T
S
R
C
S
D
E
E
R
Site 54
S792
Q
R
R
T
S
R
C
S
D
E
E
R
P
S
T
Site 55
S798
C
S
D
E
E
R
P
S
T
S
R
A
C
V
V
Site 56
T799
S
D
E
E
R
P
S
T
S
R
A
C
V
V
N
Site 57
T811
V
V
N
G
P
D
G
T
R
S
A
F
S
F
R
Site 58
S816
D
G
T
R
S
A
F
S
F
R
T
L
P
Q
G
Site 59
T819
R
S
A
F
S
F
R
T
L
P
Q
G
G
S
S
Site 60
S825
R
T
L
P
Q
G
G
S
S
G
P
A
H
D
E
Site 61
S826
T
L
P
Q
G
G
S
S
G
P
A
H
D
E
R
Site 62
T834
G
P
A
H
D
E
R
T
N
G
S
G
S
G
A
Site 63
S837
H
D
E
R
T
N
G
S
G
S
G
A
T
G
E
Site 64
S839
E
R
T
N
G
S
G
S
G
A
T
G
E
D
R
Site 65
T842
N
G
S
G
S
G
A
T
G
E
D
R
R
G
S
Site 66
S849
T
G
E
D
R
R
G
S
S
Q
P
E
S
C
D
Site 67
S850
G
E
D
R
R
G
S
S
Q
P
E
S
C
D
V
Site 68
S854
R
G
S
S
Q
P
E
S
C
D
V
Q
S
N
E
Site 69
S859
P
E
S
C
D
V
Q
S
N
E
D
Y
P
R
R
Site 70
Y863
D
V
Q
S
N
E
D
Y
P
R
R
P
L
T
R
Site 71
T869
D
Y
P
R
R
P
L
T
R
A
R
S
R
L
S
Site 72
S873
R
P
L
T
R
A
R
S
R
L
S
H
V
L
L
Site 73
S876
T
R
A
R
S
R
L
S
H
V
L
L
V
S
E
Site 74
S884
H
V
L
L
V
S
E
S
E
V
A
K
T
K
P
Site 75
T889
S
E
S
E
V
A
K
T
K
P
R
H
A
M
K
Site 76
T900
H
A
M
K
R
K
R
T
A
D
K
S
T
S
T
Site 77
S904
R
K
R
T
A
D
K
S
T
S
T
S
D
P
V
Site 78
S906
R
T
A
D
K
S
T
S
T
S
D
P
V
I
E
Site 79
S908
A
D
K
S
T
S
T
S
D
P
V
I
E
D
D
Site 80
Y975
P
I
V
N
R
F
D
Y
A
Q
C
K
K
L
N
Site 81
Y1002
P
E
R
N
R
I
I
Y
L
R
P
M
Q
Q
V
Site 82
T1011
R
P
M
Q
Q
V
D
T
L
T
L
E
Q
K
L
Site 83
T1013
M
Q
Q
V
D
T
L
T
L
E
Q
K
L
F
S
Site 84
S1020
T
L
E
Q
K
L
F
S
G
P
Y
P
Y
H
I
Site 85
T1051
R
I
R
S
W
M
D
T
I
A
N
I
N
Q
E
Site 86
Y1062
I
N
Q
E
L
I
K
Y
E
F
F
P
E
A
T
Site 87
S1071
F
F
P
E
A
T
R
S
E
E
D
L
K
K
Y
Site 88
Y1078
S
E
E
D
L
K
K
Y
P
K
Y
P
W
G
R
Site 89
Y1081
D
L
K
K
Y
P
K
Y
P
W
G
R
E
I
Y
Site 90
Y1088
Y
P
W
G
R
E
I
Y
T
L
E
G
V
V
D
Site 91
T1089
P
W
G
R
E
I
Y
T
L
E
G
V
V
D
G
Site 92
S1103
G
A
P
Y
S
M
I
S
D
F
P
W
L
R
S
Site 93
S1110
S
D
F
P
W
L
R
S
L
R
A
A
E
P
N
Site 94
S1118
L
R
A
A
E
P
N
S
F
A
R
Y
D
F
E
Site 95
Y1122
E
P
N
S
F
A
R
Y
D
F
E
D
D
E
E
Site 96
Y1133
D
D
E
E
S
T
I
Y
A
P
R
R
K
G
Q
Site 97
S1142
P
R
R
K
G
Q
L
S
A
D
I
C
M
E
T
Site 98
S1155
E
T
I
G
E
E
I
S
E
M
R
Q
M
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation