KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FIGNL1
Full Name:
Fidgetin-like protein 1
Alias:
EC 3.6.4.-; FIGL1
Type:
Hydrolase
Mass (Da):
74077
Number AA:
674
UniProt ID:
Q6PIW4
International Prot ID:
IPI00335421
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0017111
PhosphoSite+
KinaseNET
Biological Process:
GO:0046034
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
Q
T
S
S
S
R
S
V
H
L
S
E
Site 2
S8
M
Q
T
S
S
S
R
S
V
H
L
S
E
W
Q
Site 3
S12
S
S
R
S
V
H
L
S
E
W
Q
K
N
Y
F
Site 4
Y18
L
S
E
W
Q
K
N
Y
F
A
I
T
S
G
I
Site 5
Y34
T
G
P
K
A
D
A
Y
R
A
Q
I
L
R
I
Site 6
Y43
A
Q
I
L
R
I
Q
Y
A
W
A
N
S
E
I
Site 7
Y62
A
T
K
L
F
K
K
Y
A
E
K
Y
S
A
I
Site 8
Y66
F
K
K
Y
A
E
K
Y
S
A
I
I
D
S
D
Site 9
S67
K
K
Y
A
E
K
Y
S
A
I
I
D
S
D
N
Site 10
S72
K
Y
S
A
I
I
D
S
D
N
V
E
S
G
L
Site 11
T88
N
Y
A
E
N
I
L
T
L
A
G
S
Q
Q
T
Site 12
S92
N
I
L
T
L
A
G
S
Q
Q
T
D
S
D
K
Site 13
S97
A
G
S
Q
Q
T
D
S
D
K
W
Q
S
G
L
Site 14
S128
A
G
K
K
F
K
D
S
L
L
E
P
A
L
A
Site 15
S152
V
F
D
L
P
K
F
S
V
C
G
S
S
Q
E
Site 16
S156
P
K
F
S
V
C
G
S
S
Q
E
S
D
S
L
Site 17
S157
K
F
S
V
C
G
S
S
Q
E
S
D
S
L
P
Site 18
S160
V
C
G
S
S
Q
E
S
D
S
L
P
N
S
A
Site 19
S162
G
S
S
Q
E
S
D
S
L
P
N
S
A
H
D
Site 20
S166
E
S
D
S
L
P
N
S
A
H
D
R
D
R
T
Site 21
T173
S
A
H
D
R
D
R
T
Q
D
F
P
E
S
N
Site 22
S179
R
T
Q
D
F
P
E
S
N
R
L
K
L
L
Q
Site 23
T196
Q
P
P
M
V
T
N
T
A
R
T
C
P
T
F
Site 24
T202
N
T
A
R
T
C
P
T
F
S
A
P
V
G
E
Site 25
S204
A
R
T
C
P
T
F
S
A
P
V
G
E
S
A
Site 26
S231
V
K
K
E
N
H
S
S
A
K
E
N
I
G
L
Site 27
S259
C
E
N
P
Q
R
K
S
F
Y
G
S
G
T
I
Site 28
S263
Q
R
K
S
F
Y
G
S
G
T
I
D
A
L
S
Site 29
T265
K
S
F
Y
G
S
G
T
I
D
A
L
S
N
P
Site 30
S270
S
G
T
I
D
A
L
S
N
P
I
L
N
K
A
Site 31
S279
P
I
L
N
K
A
C
S
K
T
E
D
N
G
P
Site 32
T281
L
N
K
A
C
S
K
T
E
D
N
G
P
K
E
Site 33
S290
D
N
G
P
K
E
D
S
S
L
P
T
F
K
T
Site 34
S291
N
G
P
K
E
D
S
S
L
P
T
F
K
T
A
Site 35
T294
K
E
D
S
S
L
P
T
F
K
T
A
K
E
Q
Site 36
T297
S
S
L
P
T
F
K
T
A
K
E
Q
L
W
V
Site 37
Y310
W
V
D
Q
Q
K
K
Y
H
Q
P
Q
R
A
S
Site 38
S317
Y
H
Q
P
Q
R
A
S
G
S
S
Y
G
G
V
Site 39
S319
Q
P
Q
R
A
S
G
S
S
Y
G
G
V
K
K
Site 40
S320
P
Q
R
A
S
G
S
S
Y
G
G
V
K
K
S
Site 41
Y321
Q
R
A
S
G
S
S
Y
G
G
V
K
K
S
L
Site 42
S327
S
Y
G
G
V
K
K
S
L
G
A
S
R
S
R
Site 43
S331
V
K
K
S
L
G
A
S
R
S
R
G
I
L
G
Site 44
S333
K
S
L
G
A
S
R
S
R
G
I
L
G
K
F
Site 45
Y361
G
G
M
Q
C
K
P
Y
G
A
G
P
T
E
P
Site 46
T428
M
L
R
P
D
I
F
T
G
L
R
G
P
P
K
Site 47
T445
L
L
F
G
P
P
G
T
G
K
T
L
I
G
K
Site 48
S472
I
S
A
S
S
L
T
S
K
W
V
G
E
G
E
Site 49
S504
I
F
I
D
E
I
D
S
L
L
S
Q
R
G
D
Site 50
S507
D
E
I
D
S
L
L
S
Q
R
G
D
G
E
H
Site 51
S516
R
G
D
G
E
H
E
S
S
R
R
I
K
T
E
Site 52
S517
G
D
G
E
H
E
S
S
R
R
I
K
T
E
F
Site 53
T522
E
S
S
R
R
I
K
T
E
F
L
V
Q
L
D
Site 54
T545
R
I
L
V
V
G
A
T
N
R
P
Q
E
I
D
Site 55
Y564
R
R
L
V
K
R
L
Y
I
P
L
P
E
A
S
Site 56
S571
Y
I
P
L
P
E
A
S
A
R
K
Q
I
V
I
Site 57
S589
S
K
E
Q
C
C
L
S
E
E
E
I
E
Q
I
Site 58
S600
I
E
Q
I
V
Q
Q
S
D
A
F
S
G
A
D
Site 59
S604
V
Q
Q
S
D
A
F
S
G
A
D
M
T
Q
L
Site 60
T609
A
F
S
G
A
D
M
T
Q
L
C
R
E
A
S
Site 61
S616
T
Q
L
C
R
E
A
S
L
G
P
I
R
S
L
Site 62
T630
L
Q
T
A
D
I
A
T
I
T
P
D
Q
V
R
Site 63
T650
D
F
E
N
A
F
R
T
V
R
P
S
V
S
P
Site 64
S654
A
F
R
T
V
R
P
S
V
S
P
K
D
L
E
Site 65
S656
R
T
V
R
P
S
V
S
P
K
D
L
E
L
Y
Site 66
Y663
S
P
K
D
L
E
L
Y
E
N
W
N
K
T
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation