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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAPD4
Full Name:
Poly(A) RNA polymerase GLD2
Alias:
PAP-associated domain-containing protein 4
Type:
Mass (Da):
56010
Number AA:
484
UniProt ID:
Q6PIY7
International Prot ID:
IPI00167560
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0030880
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004652
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
I
L
G
R
P
P
F
T
P
N
H
Q
Q
H
N
Site 2
T24
Q
Q
H
N
N
F
F
T
L
S
P
T
V
Y
S
Site 3
T28
N
F
F
T
L
S
P
T
V
Y
S
H
Q
Q
L
Site 4
Y30
F
T
L
S
P
T
V
Y
S
H
Q
Q
L
I
D
Site 5
S48
N
F
Q
N
A
D
L
S
R
A
V
S
L
Q
Q
Site 6
S52
A
D
L
S
R
A
V
S
L
Q
Q
L
T
Y
G
Site 7
Y58
V
S
L
Q
Q
L
T
Y
G
N
V
S
P
I
Q
Site 8
S62
Q
L
T
Y
G
N
V
S
P
I
Q
T
S
A
S
Site 9
T66
G
N
V
S
P
I
Q
T
S
A
S
P
L
F
R
Site 10
S67
N
V
S
P
I
Q
T
S
A
S
P
L
F
R
G
Site 11
S69
S
P
I
Q
T
S
A
S
P
L
F
R
G
R
K
Site 12
S79
F
R
G
R
K
R
L
S
D
E
K
N
L
P
L
Site 13
S95
G
K
R
Q
R
F
H
S
P
H
Q
E
P
T
V
Site 14
T101
H
S
P
H
Q
E
P
T
V
V
N
Q
I
V
P
Site 15
S110
V
N
Q
I
V
P
L
S
G
E
R
R
Y
S
M
Site 16
Y115
P
L
S
G
E
R
R
Y
S
M
P
P
L
F
H
Site 17
S116
L
S
G
E
R
R
Y
S
M
P
P
L
F
H
T
Site 18
T148
F
L
E
P
R
E
I
T
L
P
E
A
K
D
K
Site 19
S157
P
E
A
K
D
K
L
S
Q
Q
I
L
E
L
F
Site 20
T166
Q
I
L
E
L
F
E
T
C
Q
Q
Q
I
S
D
Site 21
S172
E
T
C
Q
Q
Q
I
S
D
L
K
K
K
E
L
Site 22
T182
K
K
K
E
L
C
R
T
Q
L
Q
R
E
I
Q
Site 23
T209
S
S
L
N
G
F
G
T
R
S
S
D
G
D
L
Site 24
S211
L
N
G
F
G
T
R
S
S
D
G
D
L
C
L
Site 25
S212
N
G
F
G
T
R
S
S
D
G
D
L
C
L
V
Site 26
T233
F
F
Q
V
N
Q
K
T
E
A
R
H
I
L
T
Site 27
T240
T
E
A
R
H
I
L
T
L
V
H
K
H
F
C
Site 28
S251
K
H
F
C
T
R
L
S
G
Y
I
E
R
P
Q
Site 29
Y253
F
C
T
R
L
S
G
Y
I
E
R
P
Q
L
I
Site 30
Y297
N
T
F
L
L
R
T
Y
A
Y
L
E
N
R
V
Site 31
Y299
F
L
L
R
T
Y
A
Y
L
E
N
R
V
R
P
Site 32
S324
H
H
Q
I
N
D
A
S
R
G
T
L
S
S
Y
Site 33
T327
I
N
D
A
S
R
G
T
L
S
S
Y
S
L
V
Site 34
S351
L
P
E
P
I
L
P
S
L
Q
K
I
Y
P
E
Site 35
Y356
L
P
S
L
Q
K
I
Y
P
E
S
F
S
P
A
Site 36
S359
L
Q
K
I
Y
P
E
S
F
S
P
A
I
Q
L
Site 37
S361
K
I
Y
P
E
S
F
S
P
A
I
Q
L
H
L
Site 38
Y379
A
P
C
N
V
P
P
Y
L
S
K
N
E
S
N
Site 39
S381
C
N
V
P
P
Y
L
S
K
N
E
S
N
L
G
Site 40
S385
P
Y
L
S
K
N
E
S
N
L
G
D
L
L
L
Site 41
Y398
L
L
G
F
L
K
Y
Y
A
T
E
F
D
W
N
Site 42
S410
D
W
N
S
Q
M
I
S
V
R
E
A
K
A
I
Site 43
Y429
G
I
E
W
R
N
K
Y
I
C
V
E
E
P
F
Site 44
T441
E
P
F
D
G
T
N
T
A
R
A
V
H
E
K
Site 45
S473
K
N
K
R
D
L
N
S
I
L
P
V
R
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation