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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM65
Full Name:
Tripartite motif-containing protein 65
Alias:
Type:
Mass (Da):
57353
Number AA:
517
UniProt ID:
Q6PJ69
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
G
L
Y
Q
D
P
V
T
L
P
C
G
H
N
F
Site 2
S144
R
E
A
Q
L
R
A
S
L
E
V
T
Q
Q
Q
Site 3
T148
L
R
A
S
L
E
V
T
Q
Q
Q
A
T
Q
A
Site 4
S166
L
L
E
L
R
K
Q
S
S
Q
I
Q
N
S
A
Site 5
S167
L
E
L
R
K
Q
S
S
Q
I
Q
N
S
A
C
Site 6
S172
Q
S
S
Q
I
Q
N
S
A
C
I
L
A
S
W
Site 7
T196
Q
A
L
E
I
Q
H
T
T
A
L
R
S
I
E
Site 8
T207
R
S
I
E
V
A
K
T
Q
A
L
A
Q
A
R
Site 9
T245
L
E
Q
V
D
E
Q
T
F
L
Q
E
S
Q
L
Site 10
S250
E
Q
T
F
L
Q
E
S
Q
L
L
Q
P
P
G
Site 11
T263
P
G
P
L
G
P
L
T
P
L
Q
W
D
E
D
Site 12
S292
G
L
L
L
E
E
G
S
H
P
G
A
P
A
K
Site 13
T318
P
L
A
P
V
P
S
T
V
C
P
L
R
R
K
Site 14
T334
W
Q
N
Y
R
N
L
T
F
D
P
V
S
A
N
Site 15
Y345
V
S
A
N
R
H
F
Y
L
S
R
Q
D
Q
Q
Site 16
S347
A
N
R
H
F
Y
L
S
R
Q
D
Q
Q
V
K
Site 17
S359
Q
V
K
H
C
R
Q
S
R
G
P
G
G
P
G
Site 18
S367
R
G
P
G
G
P
G
S
F
E
L
W
Q
V
Q
Site 19
Y385
S
F
Q
A
G
H
H
Y
W
E
V
R
A
S
D
Site 20
S391
H
Y
W
E
V
R
A
S
D
H
S
V
T
L
G
Site 21
S394
E
V
R
A
S
D
H
S
V
T
L
G
V
S
Y
Site 22
T396
R
A
S
D
H
S
V
T
L
G
V
S
Y
P
Q
Site 23
S400
H
S
V
T
L
G
V
S
Y
P
Q
L
P
R
C
Site 24
Y401
S
V
T
L
G
V
S
Y
P
Q
L
P
R
C
R
Site 25
T413
R
C
R
L
G
P
H
T
D
N
I
G
R
G
P
Site 26
S447
A
Q
R
L
P
G
V
S
G
R
L
L
G
M
D
Site 27
S466
S
G
C
L
T
F
Y
S
L
E
P
Q
T
Q
P
Site 28
Y475
E
P
Q
T
Q
P
L
Y
T
F
H
A
L
F
N
Site 29
T476
P
Q
T
Q
P
L
Y
T
F
H
A
L
F
N
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation