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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf43
Full Name:
Uncharacterized protein C14orf43
Alias:
C14orf117; CN043; FLJ00335; LOC91748; LSR68
Type:
DNA binding protein
Mass (Da):
114989
Number AA:
1045
UniProt ID:
Q6PJG2
International Prot ID:
IPI00784739
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
P
L
Q
P
P
Q
Q
S
I
R
V
K
E
E
Q
Site 2
Y46
I
R
V
K
E
E
Q
Y
L
G
H
E
G
P
G
Site 3
S57
E
G
P
G
G
A
V
S
T
S
Q
P
V
E
L
Site 4
S59
P
G
G
A
V
S
T
S
Q
P
V
E
L
P
P
Site 5
S84
V
Y
G
P
E
R
T
S
A
A
M
L
S
Q
Q
Site 6
S89
R
T
S
A
A
M
L
S
Q
Q
V
A
S
V
K
Site 7
S100
A
S
V
K
W
P
N
S
V
M
A
P
G
R
G
Site 8
S117
R
G
G
G
G
G
V
S
D
S
S
W
Q
Q
Q
Site 9
S119
G
G
G
G
V
S
D
S
S
W
Q
Q
Q
P
G
Site 10
S120
G
G
G
V
S
D
S
S
W
Q
Q
Q
P
G
Q
Site 11
T133
G
Q
P
P
P
H
S
T
W
N
C
H
S
L
S
Site 12
S140
T
W
N
C
H
S
L
S
L
Y
S
A
T
K
G
Site 13
Y142
N
C
H
S
L
S
L
Y
S
A
T
K
G
S
P
Site 14
S148
L
Y
S
A
T
K
G
S
P
H
P
G
V
G
V
Site 15
Y158
P
G
V
G
V
P
T
Y
Y
N
H
P
E
A
L
Site 16
Y159
G
V
G
V
P
T
Y
Y
N
H
P
E
A
L
K
Site 17
Y178
G
G
P
Q
L
D
R
Y
V
R
P
M
M
P
Q
Site 18
S200
R
P
Q
A
P
L
N
S
F
H
A
A
K
K
P
Site 19
S211
A
K
K
P
P
N
Q
S
L
P
L
Q
P
F
Q
Site 20
Y275
M
P
L
F
E
N
F
Y
S
M
P
Q
Q
P
S
Site 21
S276
P
L
F
E
N
F
Y
S
M
P
Q
Q
P
S
Q
Site 22
S282
Y
S
M
P
Q
Q
P
S
Q
Q
P
Q
D
F
G
Site 23
Y309
A
H
H
S
M
A
P
Y
P
F
P
P
N
P
D
Site 24
S346
Q
I
P
F
P
R
R
S
R
R
L
S
K
E
G
Site 25
S350
P
R
R
S
R
R
L
S
K
E
G
I
L
P
P
Site 26
S358
K
E
G
I
L
P
P
S
A
L
D
G
A
G
T
Site 27
S389
L
Q
Q
P
P
P
G
S
L
G
Q
P
H
P
E
Site 28
S407
F
P
L
E
L
R
E
S
Q
L
L
P
D
G
E
Site 29
S430
R
E
A
P
A
M
G
S
E
E
G
M
R
A
V
Site 30
S438
E
E
G
M
R
A
V
S
T
G
D
C
G
Q
V
Site 31
S453
L
R
G
G
V
I
Q
S
T
R
R
R
R
R
A
Site 32
T454
R
G
G
V
I
Q
S
T
R
R
R
R
R
A
S
Site 33
S461
T
R
R
R
R
R
A
S
Q
E
A
N
L
L
T
Site 34
T468
S
Q
E
A
N
L
L
T
L
A
Q
K
A
V
E
Site 35
S486
L
Q
N
A
K
D
G
S
G
S
E
E
K
R
K
Site 36
S494
G
S
E
E
K
R
K
S
V
L
A
S
T
T
K
Site 37
S498
K
R
K
S
V
L
A
S
T
T
K
C
G
V
E
Site 38
S507
T
K
C
G
V
E
F
S
E
P
S
L
A
T
K
Site 39
S510
G
V
E
F
S
E
P
S
L
A
T
K
R
A
R
Site 40
S520
T
K
R
A
R
E
D
S
G
M
V
P
L
I
I
Site 41
T539
P
V
R
T
V
D
P
T
E
A
A
Q
A
G
G
Site 42
S564
N
P
A
E
H
K
P
S
V
I
V
T
R
R
R
Site 43
T568
H
K
P
S
V
I
V
T
R
R
R
S
T
R
I
Site 44
S572
V
I
V
T
R
R
R
S
T
R
I
P
G
T
D
Site 45
T573
I
V
T
R
R
R
S
T
R
I
P
G
T
D
A
Site 46
T578
R
S
T
R
I
P
G
T
D
A
Q
A
Q
A
E
Site 47
S596
V
K
L
E
G
E
P
S
V
R
K
P
K
Q
R
Site 48
Y624
T
F
I
A
P
P
V
Y
S
N
I
T
P
Y
Q
Site 49
S625
F
I
A
P
P
V
Y
S
N
I
T
P
Y
Q
S
Site 50
T628
P
P
V
Y
S
N
I
T
P
Y
Q
S
H
L
R
Site 51
Y630
V
Y
S
N
I
T
P
Y
Q
S
H
L
R
S
P
Site 52
S632
S
N
I
T
P
Y
Q
S
H
L
R
S
P
V
R
Site 53
S636
P
Y
Q
S
H
L
R
S
P
V
R
L
A
D
H
Site 54
S645
V
R
L
A
D
H
P
S
E
R
S
F
E
L
P
Site 55
S648
A
D
H
P
S
E
R
S
F
E
L
P
P
Y
T
Site 56
Y654
R
S
F
E
L
P
P
Y
T
P
P
P
I
L
S
Site 57
T655
S
F
E
L
P
P
Y
T
P
P
P
I
L
S
P
Site 58
S661
Y
T
P
P
P
I
L
S
P
V
R
E
G
S
G
Site 59
T687
I
P
A
P
P
P
I
T
P
K
S
A
H
R
T
Site 60
S690
P
P
P
I
T
P
K
S
A
H
R
T
L
L
R
Site 61
T694
T
P
K
S
A
H
R
T
L
L
R
T
N
S
A
Site 62
T698
A
H
R
T
L
L
R
T
N
S
A
E
V
T
P
Site 63
S700
R
T
L
L
R
T
N
S
A
E
V
T
P
P
V
Site 64
T704
R
T
N
S
A
E
V
T
P
P
V
L
S
V
M
Site 65
S709
E
V
T
P
P
V
L
S
V
M
G
E
A
T
P
Site 66
T715
L
S
V
M
G
E
A
T
P
V
S
I
E
P
R
Site 67
S718
M
G
E
A
T
P
V
S
I
E
P
R
I
N
V
Site 68
S727
E
P
R
I
N
V
G
S
R
F
Q
A
E
I
P
Site 69
S761
Q
P
W
E
D
L
E
S
S
R
E
K
Q
R
Q
Site 70
S798
A
L
H
C
L
H
E
S
R
G
D
I
L
E
T
Site 71
T805
S
R
G
D
I
L
E
T
L
N
K
L
L
L
K
Site 72
Y825
H
N
H
P
L
A
T
Y
H
Y
T
G
S
D
Q
Site 73
Y872
A
Q
C
V
E
F
Y
Y
T
Y
K
K
Q
V
K
Site 74
T885
V
K
I
G
R
N
G
T
L
T
F
G
D
V
D
Site 75
T887
I
G
R
N
G
T
L
T
F
G
D
V
D
T
S
Site 76
T893
L
T
F
G
D
V
D
T
S
D
E
K
S
A
Q
Site 77
S894
T
F
G
D
V
D
T
S
D
E
K
S
A
Q
E
Site 78
S898
V
D
T
S
D
E
K
S
A
Q
E
E
V
E
V
Site 79
T909
E
V
E
V
D
I
K
T
S
Q
K
F
P
R
V
Site 80
S923
V
P
L
P
R
R
E
S
P
S
E
E
R
L
E
Site 81
S925
L
P
R
R
E
S
P
S
E
E
R
L
E
P
K
Site 82
S962
Q
E
E
G
R
E
R
S
R
R
A
A
A
V
K
Site 83
S988
S
D
I
L
I
L
R
S
H
E
S
N
A
P
G
Site 84
S991
L
I
L
R
S
H
E
S
N
A
P
G
S
A
G
Site 85
S996
H
E
S
N
A
P
G
S
A
G
G
Q
A
S
E
Site 86
S1002
G
S
A
G
G
Q
A
S
E
K
P
R
E
G
T
Site 87
T1009
S
E
K
P
R
E
G
T
G
K
S
R
R
A
L
Site 88
S1012
P
R
E
G
T
G
K
S
R
R
A
L
P
F
S
Site 89
S1019
S
R
R
A
L
P
F
S
E
K
K
K
K
T
E
Site 90
T1025
F
S
E
K
K
K
K
T
E
T
F
S
K
T
Q
Site 91
T1027
E
K
K
K
K
T
E
T
F
S
K
T
Q
N
Q
Site 92
T1031
K
T
E
T
F
S
K
T
Q
N
Q
E
N
T
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation