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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C7orf27
Full Name:
BRCA1-associated protein required for ATM activation protein 1
Alias:
HEAT repeat-containing protein C7orf27
Type:
Mass (Da):
88119
Number AA:
821
UniProt ID:
Q6PJG6
International Prot ID:
IPI00658145
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
R
Q
P
V
A
D
D
T
C
L
E
K
L
L
D
Site 2
T38
K
L
L
D
W
F
K
T
V
T
E
G
E
S
S
Site 3
T40
L
D
W
F
K
T
V
T
E
G
E
S
S
V
V
Site 4
S45
T
V
T
E
G
E
S
S
V
V
L
L
Q
E
H
Site 5
Y92
A
Q
E
N
C
F
Q
Y
L
Q
Q
G
E
L
L
Site 6
T113
P
G
P
L
G
R
A
T
W
A
V
P
T
V
R
Site 7
T118
R
A
T
W
A
V
P
T
V
R
S
G
W
I
Q
Site 8
S121
W
A
V
P
T
V
R
S
G
W
I
Q
G
L
R
Site 9
S129
G
W
I
Q
G
L
R
S
L
A
Q
H
P
S
A
Site 10
S135
R
S
L
A
Q
H
P
S
A
L
R
F
L
A
D
Site 11
T148
A
D
H
G
A
V
D
T
I
F
S
L
Q
G
D
Site 12
S273
V
A
R
S
P
V
F
S
S
S
D
G
S
L
W
Site 13
S274
A
R
S
P
V
F
S
S
S
D
G
S
L
W
E
Site 14
S275
R
S
P
V
F
S
S
S
D
G
S
L
W
E
T
Site 15
S278
V
F
S
S
S
D
G
S
L
W
E
T
V
A
R
Site 16
T282
S
D
G
S
L
W
E
T
V
A
R
A
L
S
C
Site 17
T344
P
P
G
L
L
D
G
T
A
D
D
A
T
T
V
Site 18
T349
D
G
T
A
D
D
A
T
T
V
D
T
L
L
A
Site 19
T353
D
D
A
T
T
V
D
T
L
L
A
S
K
S
S
Site 20
S383
Q
P
L
P
Q
R
P
S
P
W
P
Q
A
S
L
Site 21
S437
L
D
F
L
G
T
L
S
Q
G
T
G
P
Q
E
Site 22
S462
E
C
L
E
S
P
G
S
S
P
T
V
L
K
K
Site 23
S463
C
L
E
S
P
G
S
S
P
T
V
L
K
K
A
Site 24
T465
E
S
P
G
S
S
P
T
V
L
K
K
A
F
Q
Site 25
S480
A
T
L
R
W
L
L
S
S
P
K
T
P
G
C
Site 26
S481
T
L
R
W
L
L
S
S
P
K
T
P
G
C
S
Site 27
T484
W
L
L
S
S
P
K
T
P
G
C
S
D
L
G
Site 28
S488
S
P
K
T
P
G
C
S
D
L
G
P
L
I
P
Site 29
S519
P
C
W
E
V
R
D
S
A
L
E
F
L
T
Q
Site 30
T525
D
S
A
L
E
F
L
T
Q
L
S
R
H
W
G
Site 31
S528
L
E
F
L
T
Q
L
S
R
H
W
G
G
Q
A
Site 32
S559
Q
L
L
Q
D
P
E
S
Y
V
R
A
S
A
V
Site 33
Y560
L
L
Q
D
P
E
S
Y
V
R
A
S
A
V
T
Site 34
S564
P
E
S
Y
V
R
A
S
A
V
T
A
M
G
Q
Site 35
T581
S
Q
G
L
H
A
P
T
S
P
E
H
A
E
A
Site 36
S582
Q
G
L
H
A
P
T
S
P
E
H
A
E
A
R
Site 37
S591
E
H
A
E
A
R
Q
S
L
F
L
E
L
L
H
Site 38
T671
Q
T
L
G
P
P
R
T
H
C
P
Y
A
V
A
Site 39
Y675
P
P
R
T
H
C
P
Y
A
V
A
L
P
E
V
Site 40
S732
F
L
R
D
K
I
A
S
Y
S
S
L
R
E
A
Site 41
S734
R
D
K
I
A
S
Y
S
S
L
R
E
A
R
G
Site 42
S735
D
K
I
A
S
Y
S
S
L
R
E
A
R
G
S
Site 43
S742
S
L
R
E
A
R
G
S
P
N
T
A
S
A
E
Site 44
T745
E
A
R
G
S
P
N
T
A
S
A
E
A
T
L
Site 45
S747
R
G
S
P
N
T
A
S
A
E
A
T
L
P
R
Site 46
T751
N
T
A
S
A
E
A
T
L
P
R
W
R
A
G
Site 47
S786
L
D
L
E
G
L
R
S
T
L
A
E
S
S
D
Site 48
T787
D
L
E
G
L
R
S
T
L
A
E
S
S
D
H
Site 49
S792
R
S
T
L
A
E
S
S
D
H
V
E
K
S
P
Site 50
S798
S
S
D
H
V
E
K
S
P
Q
S
L
L
Q
D
Site 51
S801
H
V
E
K
S
P
Q
S
L
L
Q
D
M
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation