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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZC3H14
Full Name:
Zinc finger CCCH domain-containing protein 14
Alias:
FLJ11806; NY-REN-37; Renal carcinoma antigen NY-REN-37; UKp68; Zinc finger CCCH-type containing 14
Type:
DNA binding protein
Mass (Da):
82876
Number AA:
736
UniProt ID:
Q6PJT7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
E
I
G
T
E
I
S
R
K
I
R
Site 2
Y25
K
L
Q
E
L
G
A
Y
V
D
E
E
L
P
D
Site 3
S43
V
M
V
A
N
K
K
S
Q
D
Q
M
T
E
D
Site 4
T48
K
K
S
Q
D
Q
M
T
E
D
L
S
L
F
L
Site 5
S52
D
Q
M
T
E
D
L
S
L
F
L
G
N
N
T
Site 6
S75
G
V
L
D
K
L
R
S
V
T
T
E
P
S
S
Site 7
T77
L
D
K
L
R
S
V
T
T
E
P
S
S
L
K
Site 8
T78
D
K
L
R
S
V
T
T
E
P
S
S
L
K
S
Site 9
S81
R
S
V
T
T
E
P
S
S
L
K
S
S
D
T
Site 10
S82
S
V
T
T
E
P
S
S
L
K
S
S
D
T
N
Site 11
S85
T
E
P
S
S
L
K
S
S
D
T
N
I
F
D
Site 12
S86
E
P
S
S
L
K
S
S
D
T
N
I
F
D
S
Site 13
T88
S
S
L
K
S
S
D
T
N
I
F
D
S
N
V
Site 14
S93
S
D
T
N
I
F
D
S
N
V
P
S
N
K
S
Site 15
S97
I
F
D
S
N
V
P
S
N
K
S
N
F
S
R
Site 16
S100
S
N
V
P
S
N
K
S
N
F
S
R
G
D
E
Site 17
S121
V
P
P
L
A
I
P
S
A
R
P
E
K
R
D
Site 18
S129
A
R
P
E
K
R
D
S
R
V
S
T
S
S
Q
Site 19
S132
E
K
R
D
S
R
V
S
T
S
S
Q
E
S
K
Site 20
T133
K
R
D
S
R
V
S
T
S
S
Q
E
S
K
T
Site 21
S135
D
S
R
V
S
T
S
S
Q
E
S
K
T
T
N
Site 22
S138
V
S
T
S
S
Q
E
S
K
T
T
N
V
R
Q
Site 23
T140
T
S
S
Q
E
S
K
T
T
N
V
R
Q
T
Y
Site 24
T141
S
S
Q
E
S
K
T
T
N
V
R
Q
T
Y
D
Site 25
T146
K
T
T
N
V
R
Q
T
Y
D
D
G
A
A
T
Site 26
Y147
T
T
N
V
R
Q
T
Y
D
D
G
A
A
T
R
Site 27
S157
G
A
A
T
R
L
M
S
T
V
K
P
L
R
E
Site 28
T158
A
A
T
R
L
M
S
T
V
K
P
L
R
E
P
Site 29
S168
P
L
R
E
P
A
P
S
E
D
V
I
D
I
K
Site 30
S195
F
V
Q
E
N
P
L
S
Q
K
K
P
T
V
T
Site 31
T200
P
L
S
Q
K
K
P
T
V
T
L
T
Y
G
S
Site 32
T202
S
Q
K
K
P
T
V
T
L
T
Y
G
S
S
R
Site 33
T204
K
K
P
T
V
T
L
T
Y
G
S
S
R
P
S
Site 34
Y205
K
P
T
V
T
L
T
Y
G
S
S
R
P
S
I
Site 35
S207
T
V
T
L
T
Y
G
S
S
R
P
S
I
E
I
Site 36
S208
V
T
L
T
Y
G
S
S
R
P
S
I
E
I
Y
Site 37
S211
T
Y
G
S
S
R
P
S
I
E
I
Y
R
P
P
Site 38
Y215
S
R
P
S
I
E
I
Y
R
P
P
A
S
R
N
Site 39
S220
E
I
Y
R
P
P
A
S
R
N
A
D
S
G
V
Site 40
S225
P
A
S
R
N
A
D
S
G
V
H
L
N
R
L
Site 41
S251
A
K
Q
L
D
M
Q
S
S
W
V
Y
E
T
G
Site 42
S252
K
Q
L
D
M
Q
S
S
W
V
Y
E
T
G
R
Site 43
Y255
D
M
Q
S
S
W
V
Y
E
T
G
R
L
C
E
Site 44
S268
C
E
P
E
V
L
N
S
L
E
E
T
Y
S
P
Site 45
T272
V
L
N
S
L
E
E
T
Y
S
P
F
F
R
N
Site 46
Y273
L
N
S
L
E
E
T
Y
S
P
F
F
R
N
N
Site 47
S274
N
S
L
E
E
T
Y
S
P
F
F
R
N
N
S
Site 48
S281
S
P
F
F
R
N
N
S
E
K
M
S
M
E
D
Site 49
S285
R
N
N
S
E
K
M
S
M
E
D
E
N
F
R
Site 50
S301
R
K
L
P
V
V
S
S
V
V
K
V
K
K
F
Site 51
Y321
E
E
E
E
D
D
D
Y
G
S
R
T
G
S
I
Site 52
S323
E
E
D
D
D
Y
G
S
R
T
G
S
I
S
S
Site 53
T325
D
D
D
Y
G
S
R
T
G
S
I
S
S
S
V
Site 54
S327
D
Y
G
S
R
T
G
S
I
S
S
S
V
S
V
Site 55
S329
G
S
R
T
G
S
I
S
S
S
V
S
V
P
A
Site 56
S330
S
R
T
G
S
I
S
S
S
V
S
V
P
A
K
Site 57
S331
R
T
G
S
I
S
S
S
V
S
V
P
A
K
P
Site 58
S333
G
S
I
S
S
S
V
S
V
P
A
K
P
E
R
Site 59
S343
A
K
P
E
R
R
P
S
L
P
P
S
K
Q
A
Site 60
S347
R
R
P
S
L
P
P
S
K
Q
A
N
K
N
L
Site 61
S365
A
I
S
E
A
Q
E
S
V
T
K
T
T
N
Y
Site 62
T367
S
E
A
Q
E
S
V
T
K
T
T
N
Y
S
T
Site 63
T369
A
Q
E
S
V
T
K
T
T
N
Y
S
T
V
P
Site 64
Y372
S
V
T
K
T
T
N
Y
S
T
V
P
Q
K
Q
Site 65
T380
S
T
V
P
Q
K
Q
T
L
P
V
A
P
R
T
Site 66
T389
P
V
A
P
R
T
R
T
S
Q
E
E
L
L
A
Site 67
S390
V
A
P
R
T
R
T
S
Q
E
E
L
L
A
E
Site 68
S403
A
E
V
V
Q
G
Q
S
R
T
P
R
I
S
P
Site 69
T405
V
V
Q
G
Q
S
R
T
P
R
I
S
P
P
I
Site 70
S409
Q
S
R
T
P
R
I
S
P
P
I
K
E
E
E
Site 71
T417
P
P
I
K
E
E
E
T
K
G
D
S
V
E
K
Site 72
S421
E
E
E
T
K
G
D
S
V
E
K
N
Q
G
T
Site 73
T428
S
V
E
K
N
Q
G
T
Q
Q
R
Q
L
L
S
Site 74
T446
I
D
P
V
M
A
E
T
L
Q
M
S
Q
D
Y
Site 75
S450
M
A
E
T
L
Q
M
S
Q
D
Y
Y
D
M
E
Site 76
Y453
T
L
Q
M
S
Q
D
Y
Y
D
M
E
S
M
V
Site 77
Y454
L
Q
M
S
Q
D
Y
Y
D
M
E
S
M
V
H
Site 78
T464
E
S
M
V
H
A
D
T
R
S
F
I
L
K
K
Site 79
S466
M
V
H
A
D
T
R
S
F
I
L
K
K
P
K
Site 80
T490
N
Q
E
S
G
M
K
T
A
D
S
L
R
V
L
Site 81
S493
S
G
M
K
T
A
D
S
L
R
V
L
S
G
H
Site 82
S498
A
D
S
L
R
V
L
S
G
H
L
M
Q
T
R
Site 83
S515
V
Q
P
D
K
P
A
S
P
K
F
I
V
T
L
Site 84
S527
V
T
L
D
G
V
P
S
P
P
G
Y
M
S
D
Site 85
Y531
G
V
P
S
P
P
G
Y
M
S
D
Q
E
E
D
Site 86
S533
P
S
P
P
G
Y
M
S
D
Q
E
E
D
M
C
Site 87
T550
G
M
K
P
V
N
Q
T
A
A
S
N
K
G
L
Site 88
S553
P
V
N
Q
T
A
A
S
N
K
G
L
R
G
L
Site 89
S570
P
Q
Q
L
H
L
L
S
R
Q
L
E
D
P
N
Site 90
S579
Q
L
E
D
P
N
G
S
F
S
N
A
E
M
S
Site 91
S581
E
D
P
N
G
S
F
S
N
A
E
M
S
E
L
Site 92
S589
N
A
E
M
S
E
L
S
V
A
Q
K
P
E
K
Site 93
Y603
K
L
L
E
R
C
K
Y
W
P
A
C
K
N
G
Site 94
Y615
K
N
G
D
E
C
A
Y
H
H
P
I
S
P
C
Site 95
S620
C
A
Y
H
H
P
I
S
P
C
K
A
F
P
N
Site 96
Y643
F
V
H
P
N
C
K
Y
D
A
K
C
T
K
P
Site 97
T655
T
K
P
D
C
P
F
T
H
V
S
R
R
I
P
Site 98
S658
D
C
P
F
T
H
V
S
R
R
I
P
V
L
S
Site 99
S665
S
R
R
I
P
V
L
S
P
K
P
A
V
A
P
Site 100
S677
V
A
P
P
A
P
P
S
S
S
Q
L
C
R
Y
Site 101
S678
A
P
P
A
P
P
S
S
S
Q
L
C
R
Y
F
Site 102
S679
P
P
A
P
P
S
S
S
Q
L
C
R
Y
F
P
Site 103
Y684
S
S
S
Q
L
C
R
Y
F
P
A
C
K
K
M
Site 104
T705
P
K
H
C
R
F
N
T
Q
C
T
R
P
D
C
Site 105
Y715
T
R
P
D
C
T
F
Y
H
P
T
I
N
V
P
Site 106
T734
L
K
W
I
R
P
Q
T
S
E
_
_
_
_
_
Site 107
S735
K
W
I
R
P
Q
T
S
E
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation