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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNST
Full Name:
Consortin
Alias:
Type:
Mass (Da):
79571
Number AA:
725
UniProt ID:
Q6PJW8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
D
D
S
D
T
P
T
Y
Y
L
Q
I
E
P
Site 2
Y9
D
D
S
D
T
P
T
Y
Y
L
Q
I
E
P
Q
Site 3
Y10
D
S
D
T
P
T
Y
Y
L
Q
I
E
P
Q
D
Site 4
S24
D
G
C
H
P
G
D
S
V
E
R
S
V
T
C
Site 5
S28
P
G
D
S
V
E
R
S
V
T
C
L
P
S
A
Site 6
T30
D
S
V
E
R
S
V
T
C
L
P
S
A
S
D
Site 7
S34
R
S
V
T
C
L
P
S
A
S
D
E
N
E
N
Site 8
S36
V
T
C
L
P
S
A
S
D
E
N
E
N
Q
L
Site 9
T52
G
D
G
H
E
H
L
T
S
S
D
S
A
M
G
Site 10
S53
D
G
H
E
H
L
T
S
S
D
S
A
M
G
K
Site 11
S54
G
H
E
H
L
T
S
S
D
S
A
M
G
K
P
Site 12
S56
E
H
L
T
S
S
D
S
A
M
G
K
P
Q
V
Site 13
S64
A
M
G
K
P
Q
V
S
E
Q
D
S
L
N
N
Site 14
S68
P
Q
V
S
E
Q
D
S
L
N
N
N
E
S
C
Site 15
S74
D
S
L
N
N
N
E
S
C
T
L
S
C
E
V
Site 16
S78
N
N
E
S
C
T
L
S
C
E
V
A
A
G
E
Site 17
T90
A
G
E
N
S
Q
N
T
L
C
E
A
S
R
D
Site 18
S113
K
K
I
P
G
K
R
S
P
R
S
K
K
G
T
Site 19
S116
P
G
K
R
S
P
R
S
K
K
G
T
A
K
K
Site 20
T120
S
P
R
S
K
K
G
T
A
K
K
I
P
P
G
Site 21
Y147
K
V
L
S
A
V
T
Y
A
V
D
D
E
E
A
Site 22
Y200
L
H
Q
I
A
E
S
Y
F
Q
E
E
D
Y
E
Site 23
Y206
S
Y
F
Q
E
E
D
Y
E
K
A
M
K
F
I
Site 24
Y219
F
I
Q
L
E
R
L
Y
H
E
Q
L
L
A
N
Site 25
S228
E
Q
L
L
A
N
L
S
A
I
Q
E
Q
W
E
Site 26
T245
W
K
T
V
Q
P
H
T
V
T
A
L
R
N
S
Site 27
S252
T
V
T
A
L
R
N
S
E
K
G
F
N
G
E
Site 28
T265
G
E
D
F
E
R
L
T
K
I
C
A
T
H
Q
Site 29
S277
T
H
Q
D
P
L
L
S
K
H
K
I
A
A
V
Site 30
S287
K
I
A
A
V
E
K
S
Q
E
R
K
C
S
T
Site 31
S293
K
S
Q
E
R
K
C
S
T
Q
L
L
V
S
E
Site 32
T294
S
Q
E
R
K
C
S
T
Q
L
L
V
S
E
D
Site 33
S299
C
S
T
Q
L
L
V
S
E
D
P
K
E
G
G
Site 34
T308
D
P
K
E
G
G
A
T
T
K
E
S
E
S
K
Site 35
S312
G
G
A
T
T
K
E
S
E
S
K
T
C
L
G
Site 36
T316
T
K
E
S
E
S
K
T
C
L
G
T
E
S
S
Site 37
T320
E
S
K
T
C
L
G
T
E
S
S
K
E
S
Q
Site 38
S322
K
T
C
L
G
T
E
S
S
K
E
S
Q
H
T
Site 39
S323
T
C
L
G
T
E
S
S
K
E
S
Q
H
T
V
Site 40
S326
G
T
E
S
S
K
E
S
Q
H
T
V
E
P
L
Site 41
T329
S
S
K
E
S
Q
H
T
V
E
P
L
G
S
S
Site 42
S336
T
V
E
P
L
G
S
S
P
C
C
H
Q
M
D
Site 43
T346
C
H
Q
M
D
V
Q
T
D
S
P
S
L
S
V
Site 44
S348
Q
M
D
V
Q
T
D
S
P
S
L
S
V
T
A
Site 45
S350
D
V
Q
T
D
S
P
S
L
S
V
T
A
G
K
Site 46
S352
Q
T
D
S
P
S
L
S
V
T
A
G
K
D
H
Site 47
T354
D
S
P
S
L
S
V
T
A
G
K
D
H
M
E
Site 48
S378
L
A
L
H
T
Q
S
S
E
T
A
G
S
P
S
Site 49
S383
Q
S
S
E
T
A
G
S
P
S
G
P
D
S
S
Site 50
S385
S
E
T
A
G
S
P
S
G
P
D
S
S
E
D
Site 51
S389
G
S
P
S
G
P
D
S
S
E
D
A
C
E
D
Site 52
S390
S
P
S
G
P
D
S
S
E
D
A
C
E
D
D
Site 53
S426
E
D
P
K
V
F
L
S
S
K
S
K
T
E
P
Site 54
S427
D
P
K
V
F
L
S
S
K
S
K
T
E
P
L
Site 55
S429
K
V
F
L
S
S
K
S
K
T
E
P
L
I
S
Site 56
T431
F
L
S
S
K
S
K
T
E
P
L
I
S
P
G
Site 57
S436
S
K
T
E
P
L
I
S
P
G
C
D
R
I
P
Site 58
S448
R
I
P
P
A
L
I
S
E
G
K
Y
S
Q
A
Site 59
Y452
A
L
I
S
E
G
K
Y
S
Q
A
Q
R
K
E
Site 60
S453
L
I
S
E
G
K
Y
S
Q
A
Q
R
K
E
L
Site 61
S468
R
L
P
L
R
D
A
S
E
A
L
P
T
D
Q
Site 62
T473
D
A
S
E
A
L
P
T
D
Q
L
E
N
N
E
Site 63
T490
E
L
Q
Q
P
D
L
T
D
S
D
G
K
S
P
Site 64
S492
Q
Q
P
D
L
T
D
S
D
G
K
S
P
Q
A
Site 65
S496
L
T
D
S
D
G
K
S
P
Q
A
Q
A
D
S
Site 66
S503
S
P
Q
A
Q
A
D
S
D
G
S
E
N
V
L
Site 67
S506
A
Q
A
D
S
D
G
S
E
N
V
L
C
G
N
Site 68
Y547
L
N
K
E
T
E
D
Y
L
N
S
L
L
E
G
Site 69
T559
L
E
G
C
L
K
D
T
E
D
S
L
S
Y
E
Site 70
S562
C
L
K
D
T
E
D
S
L
S
Y
E
D
N
Q
Site 71
S564
K
D
T
E
D
S
L
S
Y
E
D
N
Q
D
D
Site 72
S573
E
D
N
Q
D
D
D
S
D
L
L
Q
D
L
S
Site 73
S580
S
D
L
L
Q
D
L
S
P
E
E
A
S
Y
S
Site 74
Y586
L
S
P
E
E
A
S
Y
S
L
Q
E
N
L
P
Site 75
S587
S
P
E
E
A
S
Y
S
L
Q
E
N
L
P
S
Site 76
S594
S
L
Q
E
N
L
P
S
D
E
S
C
L
S
L
Site 77
S597
E
N
L
P
S
D
E
S
C
L
S
L
D
D
L
Site 78
S600
P
S
D
E
S
C
L
S
L
D
D
L
A
K
R
Site 79
S621
V
P
T
E
G
L
V
S
I
L
K
K
R
N
D
Site 80
T629
I
L
K
K
R
N
D
T
V
G
D
H
P
A
Q
Site 81
S642
A
Q
M
Q
H
K
P
S
K
R
R
V
R
F
Q
Site 82
S654
R
F
Q
E
I
D
D
S
L
D
Q
D
E
V
G
Site 83
T688
G
G
T
A
L
Y
C
T
F
G
D
M
E
S
P
Site 84
Y707
F
A
D
N
M
D
F
Y
Y
T
K
L
L
Q
G
Site 85
Y708
A
D
N
M
D
F
Y
Y
T
K
L
L
Q
G
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation