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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR179
Full Name:
Probable G-protein coupled receptor 179
Alias:
G protein-coupled receptor 179; GP179; GPR158L1; GPR158-like 1
Type:
Mass (Da):
257360
Number AA:
UniProt ID:
Q6PRD1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
G
G
P
R
P
I
R
S
L
P
P
L
S
S
Q
Site 2
S39
I
R
S
L
P
P
L
S
S
Q
V
K
P
G
S
Site 3
S40
R
S
L
P
P
L
S
S
Q
V
K
P
G
S
V
Site 4
S46
S
S
Q
V
K
P
G
S
V
P
M
Q
V
P
L
Site 5
S72
S
G
D
A
Q
Q
L
S
Q
V
N
C
S
E
R
Site 6
S77
Q
L
S
Q
V
N
C
S
E
R
Y
E
A
R
G
Site 7
Y80
Q
V
N
C
S
E
R
Y
E
A
R
G
A
G
A
Site 8
S121
Q
A
N
D
I
R
E
S
S
V
E
E
D
V
E
Site 9
S122
A
N
D
I
R
E
S
S
V
E
E
D
V
E
W
Site 10
S136
W
Y
Q
A
L
V
R
S
V
A
E
G
D
P
R
Site 11
Y145
A
E
G
D
P
R
V
Y
R
A
L
L
T
F
N
Site 12
T150
R
V
Y
R
A
L
L
T
F
N
P
P
P
G
A
Site 13
T173
A
T
R
T
G
E
E
T
I
L
Q
D
L
S
G
Site 14
T194
N
P
P
G
D
L
D
T
P
A
L
K
K
R
V
Site 15
T203
A
L
K
K
R
V
L
T
N
D
L
G
S
L
G
Site 16
S208
V
L
T
N
D
L
G
S
L
G
S
P
K
W
P
Site 17
S211
N
D
L
G
S
L
G
S
P
K
W
P
Q
A
D
Site 18
Y220
K
W
P
Q
A
D
G
Y
V
G
D
T
Q
Q
V
Site 19
T224
A
D
G
Y
V
G
D
T
Q
Q
V
R
L
S
P
Site 20
S230
D
T
Q
Q
V
R
L
S
P
P
F
L
E
C
Q
Site 21
S261
Y
G
L
K
P
D
L
S
P
E
V
R
G
Q
V
Site 22
Y315
Q
G
F
V
L
G
R
Y
L
C
R
C
R
P
G
Site 23
S327
R
P
G
F
Y
G
A
S
P
S
G
G
L
E
E
Site 24
S329
G
F
Y
G
A
S
P
S
G
G
L
E
E
S
D
Site 25
S335
P
S
G
G
L
E
E
S
D
F
Q
T
T
G
Q
Site 26
T339
L
E
E
S
D
F
Q
T
T
G
Q
F
G
F
P
Site 27
S350
F
G
F
P
E
G
R
S
G
R
L
L
Q
C
L
Site 28
Y403
F
L
S
M
L
V
S
Y
R
C
R
R
N
K
R
Site 29
S414
R
N
K
R
I
W
A
S
G
V
V
L
L
E
T
Site 30
Y460
L
L
G
F
A
I
V
Y
G
T
I
I
L
K
L
Site 31
S476
R
V
L
Q
L
F
L
S
R
T
A
Q
R
S
A
Site 32
T478
L
Q
L
F
L
S
R
T
A
Q
R
S
A
L
L
Site 33
S482
L
S
R
T
A
Q
R
S
A
L
L
S
S
G
R
Site 34
S486
A
Q
R
S
A
L
L
S
S
G
R
L
L
R
R
Site 35
S487
Q
R
S
A
L
L
S
S
G
R
L
L
R
R
L
Site 36
T528
P
L
V
I
R
G
H
T
P
S
G
R
H
F
Y
Site 37
S569
Y
A
T
R
A
V
L
S
A
F
H
E
P
R
Y
Site 38
Y576
S
A
F
H
E
P
R
Y
M
G
I
A
L
H
N
Site 39
S656
D
E
L
D
L
Q
H
S
G
S
Y
L
G
S
S
Site 40
S658
L
D
L
Q
H
S
G
S
Y
L
G
S
S
I
A
Site 41
Y659
D
L
Q
H
S
G
S
Y
L
G
S
S
I
A
S
Site 42
S662
H
S
G
S
Y
L
G
S
S
I
A
S
A
W
S
Site 43
S663
S
G
S
Y
L
G
S
S
I
A
S
A
W
S
E
Site 44
S666
Y
L
G
S
S
I
A
S
A
W
S
E
H
S
L
Site 45
S669
S
S
I
A
S
A
W
S
E
H
S
L
D
P
G
Site 46
S672
A
S
A
W
S
E
H
S
L
D
P
G
D
I
R
Site 47
Y686
R
D
E
L
K
K
L
Y
A
Q
L
E
V
H
K
Site 48
T694
A
Q
L
E
V
H
K
T
K
E
M
A
A
N
N
Site 49
S710
H
L
P
K
K
R
G
S
S
C
Q
G
L
G
R
Site 50
S711
L
P
K
K
R
G
S
S
C
Q
G
L
G
R
S
Site 51
S718
S
C
Q
G
L
G
R
S
F
M
R
Y
L
A
E
Site 52
Y722
L
G
R
S
F
M
R
Y
L
A
E
F
P
E
A
Site 53
S735
E
A
L
A
R
Q
H
S
R
D
S
G
S
P
G
Site 54
S738
A
R
Q
H
S
R
D
S
G
S
P
G
H
G
S
Site 55
S740
Q
H
S
R
D
S
G
S
P
G
H
G
S
L
P
Site 56
S745
S
G
S
P
G
H
G
S
L
P
G
S
S
R
R
Site 57
S749
G
H
G
S
L
P
G
S
S
R
R
R
L
L
S
Site 58
S750
H
G
S
L
P
G
S
S
R
R
R
L
L
S
S
Site 59
S756
S
S
R
R
R
L
L
S
S
S
L
Q
E
P
E
Site 60
S757
S
R
R
R
L
L
S
S
S
L
Q
E
P
E
G
Site 61
S758
R
R
R
L
L
S
S
S
L
Q
E
P
E
G
T
Site 62
T765
S
L
Q
E
P
E
G
T
P
A
L
H
K
S
R
Site 63
S771
G
T
P
A
L
H
K
S
R
S
T
Y
D
Q
R
Site 64
S773
P
A
L
H
K
S
R
S
T
Y
D
Q
R
R
E
Site 65
T774
A
L
H
K
S
R
S
T
Y
D
Q
R
R
E
Q
Site 66
Y775
L
H
K
S
R
S
T
Y
D
Q
R
R
E
Q
D
Site 67
S788
Q
D
P
P
L
L
D
S
L
L
R
R
K
L
A
Site 68
S799
R
K
L
A
K
K
A
S
R
T
E
S
R
E
S
Site 69
T801
L
A
K
K
A
S
R
T
E
S
R
E
S
V
E
Site 70
S803
K
K
A
S
R
T
E
S
R
E
S
V
E
G
P
Site 71
S806
S
R
T
E
S
R
E
S
V
E
G
P
P
A
L
Site 72
T824
S
A
S
A
H
N
L
T
V
G
E
R
L
P
R
Site 73
S836
L
P
R
A
R
P
A
S
L
Q
K
S
L
S
V
Site 74
S840
R
P
A
S
L
Q
K
S
L
S
V
A
S
S
R
Site 75
S842
A
S
L
Q
K
S
L
S
V
A
S
S
R
E
K
Site 76
S845
Q
K
S
L
S
V
A
S
S
R
E
K
A
L
L
Site 77
S846
K
S
L
S
V
A
S
S
R
E
K
A
L
L
M
Site 78
S855
E
K
A
L
L
M
A
S
Q
A
Y
L
E
E
T
Site 79
S881
K
A
K
A
A
M
A
S
L
V
R
R
P
S
A
Site 80
S887
A
S
L
V
R
R
P
S
A
R
R
L
E
R
P
Site 81
S900
R
P
R
G
A
P
L
S
A
P
P
S
P
A
K
Site 82
S904
A
P
L
S
A
P
P
S
P
A
K
S
S
S
V
Site 83
S908
A
P
P
S
P
A
K
S
S
S
V
D
S
S
H
Site 84
S909
P
P
S
P
A
K
S
S
S
V
D
S
S
H
T
Site 85
S910
P
S
P
A
K
S
S
S
V
D
S
S
H
T
S
Site 86
S913
A
K
S
S
S
V
D
S
S
H
T
S
G
R
L
Site 87
S914
K
S
S
S
V
D
S
S
H
T
S
G
R
L
H
Site 88
S917
S
V
D
S
S
H
T
S
G
R
L
H
E
E
A
Site 89
S955
L
G
E
P
R
M
L
S
P
T
S
T
L
A
P
Site 90
T957
E
P
R
M
L
S
P
T
S
T
L
A
P
A
L
Site 91
Y991
Q
S
P
N
L
L
T
Y
I
C
P
W
E
N
A
Site 92
S1013
N
V
P
Q
E
G
P
S
G
P
E
R
G
H
H
Site 93
S1021
G
P
E
R
G
H
H
S
P
A
P
A
R
A
R
Site 94
S1034
A
R
L
W
R
A
L
S
V
A
V
E
K
S
R
Site 95
S1040
L
S
V
A
V
E
K
S
R
A
G
E
N
E
M
Site 96
S1072
R
P
K
I
F
P
K
S
H
S
L
K
A
P
V
Site 97
S1083
K
A
P
V
Q
Q
G
S
M
R
S
L
G
L
A
Site 98
S1086
V
Q
Q
G
S
M
R
S
L
G
L
A
I
K
A
Site 99
T1095
G
L
A
I
K
A
L
T
R
S
R
S
T
Y
R
Site 100
S1099
K
A
L
T
R
S
R
S
T
Y
R
E
K
E
S
Site 101
T1100
A
L
T
R
S
R
S
T
Y
R
E
K
E
S
V
Site 102
Y1101
L
T
R
S
R
S
T
Y
R
E
K
E
S
V
E
Site 103
S1106
S
T
Y
R
E
K
E
S
V
E
E
S
P
E
G
Site 104
S1110
E
K
E
S
V
E
E
S
P
E
G
Q
N
S
G
Site 105
S1116
E
S
P
E
G
Q
N
S
G
T
A
G
E
S
M
Site 106
T1118
P
E
G
Q
N
S
G
T
A
G
E
S
M
G
A
Site 107
S1122
N
S
G
T
A
G
E
S
M
G
A
P
S
R
S
Site 108
S1127
G
E
S
M
G
A
P
S
R
S
P
R
L
G
R
Site 109
S1129
S
M
G
A
P
S
R
S
P
R
L
G
R
P
K
Site 110
S1147
K
Q
A
A
L
I
P
S
D
D
K
E
S
L
Q
Site 111
S1173
Q
V
C
Q
R
E
G
S
R
E
Q
E
D
R
G
Site 112
T1184
E
D
R
G
R
R
M
T
Q
G
L
G
E
R
K
Site 113
S1207
L
A
M
L
R
Q
V
S
R
D
K
N
I
K
Q
Site 114
T1218
N
I
K
Q
S
K
E
T
P
V
G
W
Q
E
L
Site 115
S1232
L
P
K
A
G
L
Q
S
L
G
S
A
D
H
R
Site 116
S1235
A
G
L
Q
S
L
G
S
A
D
H
R
V
A
E
Site 117
S1251
C
P
W
E
V
T
E
S
E
T
R
Q
P
D
S
Site 118
S1258
S
E
T
R
Q
P
D
S
G
N
K
A
E
I
C
Site 119
S1276
T
S
E
G
A
P
E
S
R
A
L
R
Q
D
P
Site 120
S1286
L
R
Q
D
P
G
D
S
Q
K
K
R
G
E
A
Site 121
S1297
R
G
E
A
R
G
K
S
E
P
I
D
V
V
P
Site 122
S1325
E
A
V
C
P
W
E
S
A
D
R
G
G
L
S
Site 123
S1332
S
A
D
R
G
G
L
S
P
G
S
A
P
Q
D
Site 124
S1335
R
G
G
L
S
P
G
S
A
P
Q
D
P
G
R
Site 125
S1347
P
G
R
I
R
D
K
S
E
A
G
D
S
V
E
Site 126
S1352
D
K
S
E
A
G
D
S
V
E
A
R
K
V
E
Site 127
T1372
A
A
G
P
E
A
H
T
P
D
I
T
K
A
E
Site 128
T1376
E
A
H
T
P
D
I
T
K
A
E
P
C
P
W
Site 129
T1409
L
P
Q
E
K
Q
K
T
R
K
A
T
F
W
K
Site 130
T1413
K
Q
K
T
R
K
A
T
F
W
K
E
Q
K
P
Site 131
S1426
K
P
G
G
D
L
E
S
L
C
P
W
E
S
T
Site 132
S1432
E
S
L
C
P
W
E
S
T
D
F
R
G
P
S
Site 133
T1433
S
L
C
P
W
E
S
T
D
F
R
G
P
S
A
Site 134
S1439
S
T
D
F
R
G
P
S
A
V
S
I
Q
A
P
Site 135
S1442
F
R
G
P
S
A
V
S
I
Q
A
P
G
S
S
Site 136
S1448
V
S
I
Q
A
P
G
S
S
E
C
S
G
S
L
Site 137
S1449
S
I
Q
A
P
G
S
S
E
C
S
G
S
L
G
Site 138
S1452
A
P
G
S
S
E
C
S
G
S
L
G
S
G
I
Site 139
S1454
G
S
S
E
C
S
G
S
L
G
S
G
I
A
E
Site 140
S1494
V
M
G
Q
E
M
L
S
L
G
T
G
R
E
S
Site 141
T1497
Q
E
M
L
S
L
G
T
G
R
E
S
L
Q
E
Site 142
S1501
S
L
G
T
G
R
E
S
L
Q
E
K
E
K
A
Site 143
S1513
E
K
A
S
R
K
G
S
F
G
E
M
G
E
Q
Site 144
T1521
F
G
E
M
G
E
Q
T
V
K
A
V
Q
K
L
Site 145
S1529
V
K
A
V
Q
K
L
S
Q
Q
Q
E
S
V
C
Site 146
S1534
K
L
S
Q
Q
Q
E
S
V
C
P
R
E
S
T
Site 147
S1540
E
S
V
C
P
R
E
S
T
V
P
G
H
S
S
Site 148
T1541
S
V
C
P
R
E
S
T
V
P
G
H
S
S
P
Site 149
S1547
S
T
V
P
G
H
S
S
P
C
L
D
N
S
S
Site 150
S1553
S
S
P
C
L
D
N
S
S
S
K
A
G
S
Q
Site 151
S1554
S
P
C
L
D
N
S
S
S
K
A
G
S
Q
F
Site 152
S1555
P
C
L
D
N
S
S
S
K
A
G
S
Q
F
L
Site 153
S1559
N
S
S
S
K
A
G
S
Q
F
L
C
N
G
G
Site 154
T1570
C
N
G
G
S
R
A
T
Q
V
C
P
Q
E
D
Site 155
T1586
R
P
E
A
Q
E
A
T
P
A
K
T
E
I
C
Site 156
S1607
R
T
R
E
E
W
T
S
A
Q
V
P
R
G
G
Site 157
T1633
K
S
E
I
E
D
V
T
A
W
E
K
P
E
G
Site 158
S1653
E
A
V
G
P
W
E
S
V
D
P
G
S
F
S
Site 159
S1658
W
E
S
V
D
P
G
S
F
S
P
Q
P
R
P
Site 160
S1660
S
V
D
P
G
S
F
S
P
Q
P
R
P
Q
D
Site 161
T1668
P
Q
P
R
P
Q
D
T
E
R
P
Q
T
L
L
Site 162
T1673
Q
D
T
E
R
P
Q
T
L
L
Q
M
S
G
S
Site 163
S1678
P
Q
T
L
L
Q
M
S
G
S
V
G
S
K
A
Site 164
S1680
T
L
L
Q
M
S
G
S
V
G
S
K
A
A
D
Site 165
T1698
L
D
V
E
E
N
L
T
A
G
K
A
E
I
C
Site 166
S1727
G
A
E
A
I
R
K
S
P
N
D
T
G
K
V
Site 167
T1731
I
R
K
S
P
N
D
T
G
K
V
S
A
D
L
Site 168
T1746
G
P
R
E
R
A
V
T
A
P
E
K
P
Q
K
Site 169
T1755
P
E
K
P
Q
K
P
T
P
E
W
E
V
A
C
Site 170
S1773
S
V
G
P
G
A
C
S
Q
H
P
G
T
L
D
Site 171
T1778
A
C
S
Q
H
P
G
T
L
D
A
D
G
P
K
Site 172
S1823
K
I
C
P
W
E
V
S
E
G
T
T
G
K
G
Site 173
S1837
G
L
D
Q
K
A
G
S
E
S
A
E
Q
R
E
Site 174
T1853
A
L
E
K
G
R
L
T
S
L
G
E
D
V
S
Site 175
S1854
L
E
K
G
R
L
T
S
L
G
E
D
V
S
K
Site 176
S1860
T
S
L
G
E
D
V
S
K
G
M
A
K
L
C
Site 177
S1884
E
N
K
D
L
R
E
S
P
A
Q
A
P
K
I
Site 178
S1892
P
A
Q
A
P
K
I
S
D
L
P
S
S
M
S
Site 179
S1896
P
K
I
S
D
L
P
S
S
M
S
S
E
V
A
Site 180
S1897
K
I
S
D
L
P
S
S
M
S
S
E
V
A
E
Site 181
S1899
S
D
L
P
S
S
M
S
S
E
V
A
E
G
H
Site 182
S1900
D
L
P
S
S
M
S
S
E
V
A
E
G
H
S
Site 183
S1907
S
E
V
A
E
G
H
S
L
E
A
T
E
K
G
Site 184
T1911
E
G
H
S
L
E
A
T
E
K
G
D
L
R
Q
Site 185
T1922
D
L
R
Q
D
P
K
T
G
S
F
P
E
H
I
Site 186
S1924
R
Q
D
P
K
T
G
S
F
P
E
H
I
T
Q
Site 187
T1939
E
K
A
P
A
A
D
T
E
E
F
T
T
E
D
Site 188
T1944
A
D
T
E
E
F
T
T
E
D
G
E
K
T
S
Site 189
S1951
T
E
D
G
E
K
T
S
H
E
L
Q
S
V
C
Site 190
S1956
K
T
S
H
E
L
Q
S
V
C
P
W
E
T
T
Site 191
T1962
Q
S
V
C
P
W
E
T
T
A
P
A
D
S
V
Site 192
S1968
E
T
T
A
P
A
D
S
V
S
H
L
D
R
Q
Site 193
S1970
T
A
P
A
D
S
V
S
H
L
D
R
Q
R
P
Site 194
S1983
R
P
D
Q
P
K
A
S
S
Q
R
L
V
S
T
Site 195
S1984
P
D
Q
P
K
A
S
S
Q
R
L
V
S
T
G
Site 196
S1989
A
S
S
Q
R
L
V
S
T
G
G
R
A
A
D
Site 197
Y2008
D
V
P
D
A
G
V
Y
K
S
D
S
S
A
K
Site 198
S2010
P
D
A
G
V
Y
K
S
D
S
S
A
K
A
E
Site 199
S2012
A
G
V
Y
K
S
D
S
S
A
K
A
E
T
C
Site 200
S2041
R
Q
D
G
K
G
D
S
Q
E
E
K
G
R
A
Site 201
S2052
K
G
R
A
P
E
K
S
E
P
K
G
V
P
V
Site 202
S2079
E
A
V
C
P
W
E
S
Q
D
G
K
G
L
S
Site 203
S2086
S
Q
D
G
K
G
L
S
P
Q
P
A
P
D
A
Site 204
S2094
P
Q
P
A
P
D
A
S
D
R
S
R
G
S
S
Site 205
S2097
A
P
D
A
S
D
R
S
R
G
S
S
E
A
A
Site 206
S2100
A
S
D
R
S
R
G
S
S
E
A
A
G
S
V
Site 207
S2101
S
D
R
S
R
G
S
S
E
A
A
G
S
V
E
Site 208
S2106
G
S
S
E
A
A
G
S
V
E
T
R
V
A
E
Site 209
S2149
E
G
E
Q
E
R
E
S
Q
G
Q
G
E
M
F
Site 210
S2170
G
G
T
E
E
H
F
S
K
A
A
A
K
P
R
Site 211
S2190
C
P
G
E
G
T
G
S
G
G
L
L
P
Q
S
Site 212
S2197
S
G
G
L
L
P
Q
S
G
A
L
D
P
E
L
Site 213
S2207
L
D
P
E
L
K
V
S
P
K
E
A
G
S
M
Site 214
S2213
V
S
P
K
E
A
G
S
M
G
S
R
M
A
E
Site 215
T2237
E
G
N
K
I
K
G
T
M
A
D
I
C
P
G
Site 216
T2247
D
I
C
P
G
E
E
T
G
V
P
S
E
E
S
Site 217
S2251
G
E
E
T
G
V
P
S
E
E
S
G
L
L
A
Site 218
T2269
T
R
R
E
F
F
P
T
A
P
E
K
P
L
C
Site 219
S2298
K
I
P
C
P
K
V
S
R
P
A
S
T
F
T
Site 220
S2302
P
K
V
S
R
P
A
S
T
F
T
L
E
G
V
Site 221
T2305
S
R
P
A
S
T
F
T
L
E
G
V
R
E
L
Site 222
S2323
S
G
L
E
P
R
T
S
L
A
P
E
P
S
L
Site 223
S2329
T
S
L
A
P
E
P
S
L
Q
E
A
E
S
Q
Site 224
S2335
P
S
L
Q
E
A
E
S
Q
S
S
S
L
T
E
Site 225
S2338
Q
E
A
E
S
Q
S
S
S
L
T
E
D
S
G
Site 226
S2339
E
A
E
S
Q
S
S
S
L
T
E
D
S
G
Q
Site 227
T2341
E
S
Q
S
S
S
L
T
E
D
S
G
Q
V
A
Site 228
S2344
S
S
S
L
T
E
D
S
G
Q
V
A
F
E
A
Site 229
Y2353
Q
V
A
F
E
A
Q
Y
E
E
F
T
P
P
T
Site 230
T2357
E
A
Q
Y
E
E
F
T
P
P
T
V
Y
P
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation