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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAF7
Full Name:
E3 ubiquitin-protein ligase TRAF7
Alias:
DKFZp586I021; E3 ubiquitin protein ligase TRAF7; E3 ubiquitin-protein ligase TRAF7: TNF receptor-associated factor 7: RING finger and WD repeat-containing protein 1: RING finger protein 119; MGC7807; RFWD1; RING finger and WD repeat domain protein 1; RNF119; TNF receptor-associated factor 7
Type:
Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.-; Ligase
Mass (Da):
74609
Number AA:
670
UniProt ID:
Q6Q0C0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016023
GO:0000151
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0004842
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000185
GO:0006915
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
S
G
K
S
A
R
Y
N
R
F
S
Site 2
Y9
S
S
G
K
S
A
R
Y
N
R
F
S
G
G
P
Site 3
S13
S
A
R
Y
N
R
F
S
G
G
P
S
N
L
P
Site 4
S17
N
R
F
S
G
G
P
S
N
L
P
T
P
D
V
Site 5
T21
G
G
P
S
N
L
P
T
P
D
V
T
T
G
T
Site 6
T32
T
T
G
T
R
M
E
T
T
F
G
P
A
F
S
Site 7
T33
T
G
T
R
M
E
T
T
F
G
P
A
F
S
A
Site 8
T59
T
Y
K
Q
H
C
R
T
P
S
S
S
S
T
L
Site 9
S61
K
Q
H
C
R
T
P
S
S
S
S
T
L
A
Y
Site 10
S62
Q
H
C
R
T
P
S
S
S
S
T
L
A
Y
S
Site 11
S63
H
C
R
T
P
S
S
S
S
T
L
A
Y
S
P
Site 12
S64
C
R
T
P
S
S
S
S
T
L
A
Y
S
P
R
Site 13
T65
R
T
P
S
S
S
S
T
L
A
Y
S
P
R
D
Site 14
Y68
S
S
S
S
T
L
A
Y
S
P
R
D
E
E
D
Site 15
S69
S
S
S
T
L
A
Y
S
P
R
D
E
E
D
S
Site 16
S76
S
P
R
D
E
E
D
S
M
P
P
I
S
T
P
Site 17
S81
E
D
S
M
P
P
I
S
T
P
R
R
S
D
S
Site 18
T82
D
S
M
P
P
I
S
T
P
R
R
S
D
S
A
Site 19
S86
P
I
S
T
P
R
R
S
D
S
A
I
S
V
R
Site 20
S88
S
T
P
R
R
S
D
S
A
I
S
V
R
S
L
Site 21
S91
R
R
S
D
S
A
I
S
V
R
S
L
H
S
E
Site 22
S94
D
S
A
I
S
V
R
S
L
H
S
E
S
S
M
Site 23
S97
I
S
V
R
S
L
H
S
E
S
S
M
S
L
R
Site 24
S99
V
R
S
L
H
S
E
S
S
M
S
L
R
S
T
Site 25
S100
R
S
L
H
S
E
S
S
M
S
L
R
S
T
F
Site 26
S102
L
H
S
E
S
S
M
S
L
R
S
T
F
S
L
Site 27
S105
E
S
S
M
S
L
R
S
T
F
S
L
P
E
E
Site 28
T106
S
S
M
S
L
R
S
T
F
S
L
P
E
E
E
Site 29
S108
M
S
L
R
S
T
F
S
L
P
E
E
E
E
E
Site 30
S197
H
G
C
R
V
A
G
S
G
K
P
P
I
F
E
Site 31
T213
D
P
R
G
C
P
F
T
I
K
L
S
A
R
K
Site 32
S217
C
P
F
T
I
K
L
S
A
R
K
D
H
E
G
Site 33
Y228
D
H
E
G
S
C
D
Y
R
P
V
R
C
P
N
Site 34
S238
V
R
C
P
N
N
P
S
C
P
P
L
L
R
M
Site 35
Y264
I
K
C
P
H
S
K
Y
G
C
T
F
I
G
N
Site 36
T274
T
F
I
G
N
Q
D
T
Y
E
T
H
L
E
T
Site 37
Y275
F
I
G
N
Q
D
T
Y
E
T
H
L
E
T
C
Site 38
T294
L
K
E
F
L
Q
Q
T
D
D
R
F
H
E
M
Site 39
S332
K
I
D
Q
L
E
K
S
L
E
L
K
F
D
V
Site 40
S359
M
E
F
R
R
D
A
S
M
L
N
D
E
L
S
Site 41
S366
S
M
L
N
D
E
L
S
H
I
N
A
R
L
N
Site 42
Y380
N
M
G
I
L
G
S
Y
D
P
Q
Q
I
F
K
Site 43
S413
S
M
G
D
L
L
F
S
G
S
S
D
K
T
I
Site 44
S415
G
D
L
L
F
S
G
S
S
D
K
T
I
K
V
Site 45
T419
F
S
G
S
S
D
K
T
I
K
V
W
D
T
C
Site 46
Y429
V
W
D
T
C
T
T
Y
K
C
Q
K
T
L
E
Site 47
T434
T
T
Y
K
C
Q
K
T
L
E
G
H
D
G
I
Site 48
T474
Q
N
L
Q
K
V
N
T
I
R
A
H
D
N
P
Site 49
T484
A
H
D
N
P
V
C
T
L
V
S
S
H
N
V
Site 50
S494
S
S
H
N
V
L
F
S
G
S
L
K
A
I
K
Site 51
T517
L
K
L
K
K
E
L
T
G
L
N
H
W
V
R
Site 52
S531
R
A
L
V
A
A
Q
S
Y
L
Y
S
G
S
Y
Site 53
S535
A
A
Q
S
Y
L
Y
S
G
S
Y
Q
T
I
K
Site 54
Y538
S
Y
L
Y
S
G
S
Y
Q
T
I
K
I
W
D
Site 55
S564
T
S
G
G
S
V
Y
S
I
A
V
T
N
H
H
Site 56
T594
E
S
K
E
Q
V
R
T
L
T
G
H
V
G
T
Site 57
T596
K
E
Q
V
R
T
L
T
G
H
V
G
T
V
Y
Site 58
T614
V
I
S
T
P
D
Q
T
K
V
F
S
A
S
Y
Site 59
S620
Q
T
K
V
F
S
A
S
Y
D
R
S
L
R
V
Site 60
Y621
T
K
V
F
S
A
S
Y
D
R
S
L
R
V
W
Site 61
S624
F
S
A
S
Y
D
R
S
L
R
V
W
S
M
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation