KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LVRN
Full Name:
Aminopeptidase Q
Alias:
CHL2; CHL2 antigen; Laeverin; LAEVR
Type:
Protease; EC 3.4.-.-
Mass (Da):
113272
Number AA:
990
UniProt ID:
Q6Q4G3
International Prot ID:
IPI00419976
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0008237
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
P
P
S
S
S
G
F
Y
V
S
R
Site 2
S7
_
M
G
P
P
S
S
S
G
F
Y
V
S
R
A
Site 3
S12
S
S
S
G
F
Y
V
S
R
A
V
A
L
L
L
Site 4
S46
H
C
E
R
V
P
P
S
E
L
P
G
L
R
D
Site 5
S54
E
L
P
G
L
R
D
S
E
A
E
S
S
P
P
Site 6
S58
L
R
D
S
E
A
E
S
S
P
P
L
R
Q
K
Site 7
S59
R
D
S
E
A
E
S
S
P
P
L
R
Q
K
P
Site 8
T67
P
P
L
R
Q
K
P
T
P
T
P
K
P
S
S
Site 9
T69
L
R
Q
K
P
T
P
T
P
K
P
S
S
A
R
Site 10
S73
P
T
P
T
P
K
P
S
S
A
R
E
L
A
V
Site 11
S74
T
P
T
P
K
P
S
S
A
R
E
L
A
V
T
Site 12
T81
S
A
R
E
L
A
V
T
T
T
P
S
N
W
R
Site 13
T83
R
E
L
A
V
T
T
T
P
S
N
W
R
P
P
Site 14
S85
L
A
V
T
T
T
P
S
N
W
R
P
P
G
P
Site 15
Y107
P
W
L
V
P
L
H
Y
D
L
E
L
W
P
Q
Site 16
S124
P
D
E
L
P
A
G
S
L
P
F
T
G
R
V
Site 17
S148
T
S
R
L
L
L
H
S
L
F
Q
D
C
E
R
Site 18
S163
A
E
V
R
G
P
L
S
P
G
T
G
N
A
T
Site 19
T166
R
G
P
L
S
P
G
T
G
N
A
T
V
G
R
Site 20
T170
S
P
G
T
G
N
A
T
V
G
R
V
P
V
D
Site 21
S193
E
Y
M
V
L
E
L
S
E
P
L
K
P
G
S
Site 22
S200
S
E
P
L
K
P
G
S
S
Y
E
L
Q
L
S
Site 23
S201
E
P
L
K
P
G
S
S
Y
E
L
Q
L
S
F
Site 24
S207
S
S
Y
E
L
Q
L
S
F
S
G
L
V
K
E
Site 25
S209
Y
E
L
Q
L
S
F
S
G
L
V
K
E
D
L
Site 26
Y225
E
G
L
F
L
N
V
Y
T
D
Q
G
E
R
R
Site 27
S237
E
R
R
A
L
L
A
S
Q
L
E
P
T
F
A
Site 28
Y246
L
E
P
T
F
A
R
Y
V
F
P
C
F
D
E
Site 29
T259
D
E
P
A
L
K
A
T
F
N
I
T
M
I
H
Site 30
Y270
T
M
I
H
H
P
S
Y
V
A
L
S
N
M
P
Site 31
S274
H
P
S
Y
V
A
L
S
N
M
P
K
L
G
Q
Site 32
S290
E
K
E
D
V
N
G
S
K
W
T
V
T
T
F
Site 33
T293
D
V
N
G
S
K
W
T
V
T
T
F
S
T
T
Site 34
T295
N
G
S
K
W
T
V
T
T
F
S
T
T
P
H
Site 35
T296
G
S
K
W
T
V
T
T
F
S
T
T
P
H
M
Site 36
T300
T
V
T
T
F
S
T
T
P
H
M
P
T
Y
L
Site 37
Y315
V
A
F
V
I
C
D
Y
D
H
V
N
R
T
E
Site 38
Y363
E
D
L
F
N
I
S
Y
S
L
P
K
T
D
I
Site 39
S375
T
D
I
I
A
L
P
S
F
D
N
H
A
M
E
Site 40
T403
L
E
P
K
D
Q
L
T
E
K
K
T
L
I
S
Site 41
T407
D
Q
L
T
E
K
K
T
L
I
S
Y
V
V
S
Site 42
S410
T
E
K
K
T
L
I
S
Y
V
V
S
H
E
I
Site 43
Y411
E
K
K
T
L
I
S
Y
V
V
S
H
E
I
G
Site 44
Y451
F
E
F
E
V
I
N
Y
F
N
P
K
L
P
R
Site 45
T491
M
K
V
E
N
F
K
T
S
E
I
Q
E
L
F
Site 46
T502
Q
E
L
F
D
I
F
T
Y
S
K
G
A
S
M
Site 47
T532
A
L
K
S
Y
L
K
T
F
S
Y
S
N
A
E
Site 48
Y535
S
Y
L
K
T
F
S
Y
S
N
A
E
Q
D
D
Site 49
Y594
V
M
K
Q
E
P
F
Y
L
E
N
I
K
N
R
Site 50
S606
K
N
R
T
L
L
T
S
N
D
T
W
I
V
P
Site 51
S631
P
L
V
W
L
D
Q
S
S
K
V
F
P
E
M
Site 52
S643
P
E
M
Q
V
S
D
S
D
H
D
W
V
I
L
Site 53
Y657
L
N
L
N
M
T
G
Y
Y
R
V
N
Y
D
K
Site 54
Y662
T
G
Y
Y
R
V
N
Y
D
K
L
G
W
K
K
Site 55
S695
Q
F
I
D
D
A
F
S
L
S
K
N
N
Y
I
Site 56
S697
I
D
D
A
F
S
L
S
K
N
N
Y
I
E
I
Site 57
Y701
F
S
L
S
K
N
N
Y
I
E
I
E
T
A
L
Site 58
Y713
T
A
L
E
L
T
K
Y
L
A
E
E
D
E
I
Site 59
Y745
E
V
N
I
Y
D
I
Y
S
L
L
K
R
Y
L
Site 60
S803
L
E
D
C
L
Q
L
S
K
E
L
F
A
K
W
Site 61
Y820
H
P
E
N
E
I
P
Y
P
I
K
D
V
V
L
Site 62
T845
E
W
D
I
L
L
N
T
Y
T
N
T
T
N
K
Site 63
Y874
D
P
W
I
L
N
R
Y
M
E
Y
A
I
S
T
Site 64
S880
R
Y
M
E
Y
A
I
S
T
S
P
F
T
S
N
Site 65
S882
M
E
Y
A
I
S
T
S
P
F
T
S
N
E
T
Site 66
S886
I
S
T
S
P
F
T
S
N
E
T
N
I
I
E
Site 67
S924
S
K
R
Y
G
T
Q
S
L
I
N
L
I
Y
T
Site 68
S979
N
L
K
N
K
K
L
S
A
R
I
A
A
W
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation