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Updated November 2019
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Protein Info
Short Name:
SPAG17
Full Name:
Sperm-associated antigen 17
Alias:
FLJ34497; PF6; projection protein PF6; RP4-776P7.2; sperm associated antigen 17
Type:
Cytoskeletal protein
Mass (Da):
251742
Number AA:
2223
UniProt ID:
Q6Q759
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005929
GO:0005737
GO:0035086
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
P
K
K
E
K
G
G
T
V
N
T
S
S
K
I
Site 2
S15
G
G
T
V
N
T
S
S
K
I
W
E
P
S
L
Site 3
S21
S
S
K
I
W
E
P
S
L
I
A
A
Q
F
N
Site 4
S66
V
P
Q
R
K
L
F
S
M
V
S
W
Q
D
I
Site 5
S69
R
K
L
F
S
M
V
S
W
Q
D
I
L
Q
Q
Site 6
T82
Q
Q
I
N
E
I
N
T
L
V
G
S
A
S
S
Site 7
S86
E
I
N
T
L
V
G
S
A
S
S
K
K
A
K
Site 8
S88
N
T
L
V
G
S
A
S
S
K
K
A
K
K
P
Site 9
S166
K
D
K
G
K
A
K
S
P
K
E
K
K
A
P
Site 10
T207
R
R
G
E
D
D
H
T
N
R
Y
I
D
D
E
Site 11
Y210
E
D
D
H
T
N
R
Y
I
D
D
E
P
D
D
Site 12
Y255
I
K
I
S
S
E
N
Y
E
P
L
Q
T
H
L
Site 13
T260
E
N
Y
E
P
L
Q
T
H
L
A
A
V
N
Q
Site 14
T294
N
A
I
K
E
L
K
T
F
W
K
Y
L
E
P
Site 15
Y298
E
L
K
T
F
W
K
Y
L
E
P
V
L
N
N
Site 16
T310
L
N
N
E
K
P
E
T
N
L
F
D
V
A
R
Site 17
S329
V
K
A
A
D
F
P
S
D
W
S
D
G
E
M
Site 18
S332
A
D
F
P
S
D
W
S
D
G
E
M
M
L
K
Site 19
Y365
W
K
R
Q
H
Q
H
Y
L
E
S
M
Q
L
I
Site 20
T389
P
V
L
E
A
M
P
T
S
E
A
P
Q
P
A
Site 21
Y407
P
G
K
K
K
A
Q
Y
E
E
P
Q
A
P
P
Site 22
T422
P
V
T
S
V
I
T
T
E
V
D
M
R
Y
Y
Site 23
Y428
T
T
E
V
D
M
R
Y
Y
N
Y
L
L
N
P
Site 24
Y429
T
E
V
D
M
R
Y
Y
N
Y
L
L
N
P
I
Site 25
S465
E
E
D
L
V
P
P
S
L
R
E
P
S
P
R
Site 26
S470
P
P
S
L
R
E
P
S
P
R
A
D
G
L
D
Site 27
S494
L
L
P
S
L
C
L
S
E
R
E
K
K
N
L
Site 28
S507
N
L
H
D
I
F
L
S
E
E
E
N
E
S
K
Site 29
S513
L
S
E
E
E
N
E
S
K
A
V
P
K
G
P
Site 30
Y525
K
G
P
L
L
L
N
Y
H
D
A
H
A
H
K
Site 31
T577
N
N
T
K
R
L
A
T
I
H
E
L
M
H
F
Site 32
S591
F
C
T
S
D
V
L
S
W
N
E
V
E
R
A
Site 33
T603
E
R
A
F
K
V
F
T
F
E
S
L
K
L
S
Site 34
S610
T
F
E
S
L
K
L
S
E
V
D
E
K
G
K
Site 35
S621
E
K
G
K
L
K
P
S
G
M
M
C
G
S
D
Site 36
Y650
A
K
Q
I
R
Q
Q
Y
V
M
K
M
N
T
Q
Site 37
T671
D
I
K
I
K
D
R
T
L
F
V
D
Q
N
L
Site 38
S679
L
F
V
D
Q
N
L
S
M
S
V
Q
D
N
E
Site 39
S681
V
D
Q
N
L
S
M
S
V
Q
D
N
E
S
N
Site 40
S687
M
S
V
Q
D
N
E
S
N
R
E
P
S
D
P
Site 41
S692
N
E
S
N
R
E
P
S
D
P
S
Q
C
D
A
Site 42
S695
N
R
E
P
S
D
P
S
Q
C
D
A
N
N
M
Site 43
S705
D
A
N
N
M
K
H
S
D
L
N
N
L
K
L
Site 44
S713
D
L
N
N
L
K
L
S
V
P
D
N
R
Q
L
Site 45
S725
R
Q
L
L
E
Q
E
S
I
M
K
A
Q
P
Q
Site 46
S735
K
A
Q
P
Q
H
E
S
L
E
Q
T
T
N
N
Site 47
T739
Q
H
E
S
L
E
Q
T
T
N
N
E
I
K
D
Site 48
T750
E
I
K
D
D
A
V
T
K
A
D
S
H
E
K
Site 49
S754
D
A
V
T
K
A
D
S
H
E
K
K
P
K
K
Site 50
T774
D
L
E
D
I
K
K
T
Q
Q
R
S
L
M
D
Site 51
S778
I
K
K
T
Q
Q
R
S
L
M
D
W
S
F
T
Site 52
Y804
L
Q
E
A
H
K
Q
Y
R
C
V
D
S
Y
Y
Site 53
Y810
Q
Y
R
C
V
D
S
Y
Y
H
T
Q
D
N
S
Site 54
Y811
Y
R
C
V
D
S
Y
Y
H
T
Q
D
N
S
L
Site 55
T813
C
V
D
S
Y
Y
H
T
Q
D
N
S
L
L
L
Site 56
Y835
R
Q
R
L
H
C
E
Y
W
N
I
A
L
H
S
Site 57
Y849
S
N
V
G
F
R
N
Y
L
E
L
V
A
K
S
Site 58
T862
K
S
I
Q
D
W
I
T
K
E
E
A
I
Y
Q
Site 59
Y868
I
T
K
E
E
A
I
Y
Q
E
S
K
M
N
E
Site 60
S889
A
E
L
E
L
K
S
S
A
N
A
K
L
T
S
Site 61
T895
S
S
A
N
A
K
L
T
S
A
S
K
I
F
S
Site 62
S898
N
A
K
L
T
S
A
S
K
I
F
S
I
K
E
Site 63
S902
T
S
A
S
K
I
F
S
I
K
E
S
K
S
N
Site 64
S906
K
I
F
S
I
K
E
S
K
S
N
K
G
I
S
Site 65
S908
F
S
I
K
E
S
K
S
N
K
G
I
S
K
T
Site 66
S913
S
K
S
N
K
G
I
S
K
T
E
I
S
D
Q
Site 67
T915
S
N
K
G
I
S
K
T
E
I
S
D
Q
E
K
Site 68
S918
G
I
S
K
T
E
I
S
D
Q
E
K
E
K
E
Site 69
S980
D
N
A
E
K
E
D
S
R
S
L
K
K
K
S
Site 70
S982
A
E
K
E
D
S
R
S
L
K
K
K
S
P
Y
Site 71
S987
S
R
S
L
K
K
K
S
P
Y
K
E
K
S
K
Site 72
Y989
S
L
K
K
K
S
P
Y
K
E
K
S
K
E
E
Site 73
S993
K
S
P
Y
K
E
K
S
K
E
E
Q
V
K
I
Site 74
S1007
I
Q
E
V
T
E
E
S
P
H
Q
P
E
P
K
Site 75
Y1017
Q
P
E
P
K
I
T
Y
P
F
H
G
Y
N
M
Site 76
T1029
Y
N
M
G
N
I
P
T
Q
I
S
G
S
N
Y
Site 77
S1034
I
P
T
Q
I
S
G
S
N
Y
Y
L
Y
P
S
Site 78
Y1036
T
Q
I
S
G
S
N
Y
Y
L
Y
P
S
D
G
Site 79
Y1037
Q
I
S
G
S
N
Y
Y
L
Y
P
S
D
G
G
Site 80
Y1039
S
G
S
N
Y
Y
L
Y
P
S
D
G
G
Q
I
Site 81
S1041
S
N
Y
Y
L
Y
P
S
D
G
G
Q
I
E
V
Site 82
T1051
G
Q
I
E
V
E
K
T
M
F
E
K
G
P
T
Site 83
Y1090
K
K
E
E
K
G
D
Y
Y
L
E
E
E
E
E
Site 84
Y1091
K
E
E
K
G
D
Y
Y
L
E
E
E
E
E
G
Site 85
S1103
E
E
G
D
E
E
Q
S
L
E
T
E
V
S
D
Site 86
S1109
Q
S
L
E
T
E
V
S
D
A
K
N
K
A
F
Site 87
S1117
D
A
K
N
K
A
F
S
K
F
G
S
F
S
A
Site 88
S1121
K
A
F
S
K
F
G
S
F
S
A
T
L
E
N
Site 89
S1133
L
E
N
G
I
C
L
S
I
S
Y
Y
G
S
N
Site 90
S1135
N
G
I
C
L
S
I
S
Y
Y
G
S
N
G
M
Site 91
S1139
L
S
I
S
Y
Y
G
S
N
G
M
A
P
E
D
Site 92
T1153
D
K
D
P
D
L
E
T
I
L
N
I
P
S
A
Site 93
T1171
T
V
V
P
V
I
V
T
V
P
Q
S
K
A
K
Site 94
S1175
V
I
V
T
V
P
Q
S
K
A
K
G
K
I
K
Site 95
S1190
G
K
E
K
P
K
E
S
L
K
E
E
E
H
P
Site 96
T1221
Q
E
T
L
D
V
P
T
F
Q
S
L
N
V
S
Site 97
Y1246
G
Q
E
S
T
G
Q
Y
V
I
D
E
E
P
T
Site 98
Y1262
D
I
M
V
R
Q
S
Y
P
Q
R
V
K
H
Y
Site 99
Y1272
R
V
K
H
Y
E
F
Y
K
T
V
M
P
P
A
Site 100
T1274
K
H
Y
E
F
Y
K
T
V
M
P
P
A
E
Q
Site 101
S1284
P
P
A
E
Q
E
A
S
R
V
I
T
S
Q
G
Site 102
T1288
Q
E
A
S
R
V
I
T
S
Q
G
T
V
V
K
Site 103
S1289
E
A
S
R
V
I
T
S
Q
G
T
V
V
K
Y
Site 104
Y1296
S
Q
G
T
V
V
K
Y
M
L
D
G
S
T
Q
Site 105
S1312
L
F
A
D
G
A
V
S
R
S
P
N
S
G
L
Site 106
S1314
A
D
G
A
V
S
R
S
P
N
S
G
L
I
C
Site 107
S1317
A
V
S
R
S
P
N
S
G
L
I
C
P
P
S
Site 108
S1324
S
G
L
I
C
P
P
S
E
M
P
A
T
P
H
Site 109
T1329
P
P
S
E
M
P
A
T
P
H
S
G
D
L
M
Site 110
S1332
E
M
P
A
T
P
H
S
G
D
L
M
D
S
I
Site 111
S1338
H
S
G
D
L
M
D
S
I
S
Q
Q
K
S
E
Site 112
S1340
G
D
L
M
D
S
I
S
Q
Q
K
S
E
T
I
Site 113
S1344
D
S
I
S
Q
Q
K
S
E
T
I
P
S
E
I
Site 114
S1349
Q
K
S
E
T
I
P
S
E
I
T
N
T
K
K
Site 115
T1352
E
T
I
P
S
E
I
T
N
T
K
K
G
K
S
Site 116
T1354
I
P
S
E
I
T
N
T
K
K
G
K
S
H
K
Site 117
S1359
T
N
T
K
K
G
K
S
H
K
S
Q
S
S
M
Site 118
S1362
K
K
G
K
S
H
K
S
Q
S
S
M
A
H
K
Site 119
S1365
K
S
H
K
S
Q
S
S
M
A
H
K
G
E
I
Site 120
T1382
P
P
P
E
A
V
Q
T
V
T
P
V
E
V
H
Site 121
T1397
I
G
T
W
F
T
T
T
P
E
G
N
R
I
G
Site 122
T1405
P
E
G
N
R
I
G
T
K
G
L
E
R
I
A
Site 123
T1432
P
V
N
G
T
V
M
T
T
R
E
D
K
V
V
Site 124
T1433
V
N
G
T
V
M
T
T
R
E
D
K
V
V
I
Site 125
T1460
A
D
G
T
R
I
T
T
F
Y
Q
V
Y
E
D
Site 126
Y1462
G
T
R
I
T
T
F
Y
Q
V
Y
E
D
Q
I
Site 127
T1483
E
T
T
E
G
P
R
T
V
T
R
Q
V
K
C
Site 128
T1485
T
E
G
P
R
T
V
T
R
Q
V
K
C
M
R
Site 129
Y1498
M
R
V
E
S
S
R
Y
A
T
V
I
A
N
C
Site 130
T1500
V
E
S
S
R
Y
A
T
V
I
A
N
C
E
D
Site 131
T1513
E
D
S
S
C
C
A
T
F
G
D
G
T
T
I
Site 132
T1519
A
T
F
G
D
G
T
T
I
I
A
K
P
Q
G
Site 133
Y1539
P
P
N
T
G
S
L
Y
I
D
K
D
C
S
A
Site 134
Y1548
D
K
D
C
S
A
V
Y
C
H
E
S
S
S
N
Site 135
Y1557
H
E
S
S
S
N
I
Y
Y
P
F
Q
K
R
E
Site 136
Y1558
E
S
S
S
N
I
Y
Y
P
F
Q
K
R
E
Q
Site 137
Y1571
E
Q
L
R
A
G
R
Y
I
M
R
H
T
S
E
Site 138
T1576
G
R
Y
I
M
R
H
T
S
E
V
I
C
E
V
Site 139
T1616
E
D
D
L
N
E
K
T
E
G
Y
D
S
L
S
Site 140
Y1619
L
N
E
K
T
E
G
Y
D
S
L
S
S
M
H
Site 141
S1621
E
K
T
E
G
Y
D
S
L
S
S
M
H
L
E
Site 142
S1623
T
E
G
Y
D
S
L
S
S
M
H
L
E
K
N
Site 143
Y1635
E
K
N
H
Q
Q
I
Y
G
E
H
V
P
R
F
Site 144
S1658
G
M
E
L
L
R
D
S
D
I
E
E
Y
L
S
Site 145
Y1663
R
D
S
D
I
E
E
Y
L
S
L
A
Y
K
E
Site 146
S1665
S
D
I
E
E
Y
L
S
L
A
Y
K
E
S
N
Site 147
T1686
P
V
Q
E
Q
P
G
T
L
T
I
T
V
L
R
Site 148
T1690
Q
P
G
T
L
T
I
T
V
L
R
P
F
H
E
Site 149
S1699
L
R
P
F
H
E
A
S
P
W
Q
V
K
K
E
Site 150
T1708
W
Q
V
K
K
E
D
T
I
V
P
P
N
L
R
Site 151
S1716
I
V
P
P
N
L
R
S
R
S
W
E
T
F
P
Site 152
S1718
P
P
N
L
R
S
R
S
W
E
T
F
P
S
V
Site 153
T1721
L
R
S
R
S
W
E
T
F
P
S
V
E
K
K
Site 154
S1724
R
S
W
E
T
F
P
S
V
E
K
K
T
P
G
Site 155
T1729
F
P
S
V
E
K
K
T
P
G
P
P
F
G
T
Site 156
S1746
W
K
G
L
C
I
E
S
K
Q
L
V
S
A
P
Site 157
S1751
I
E
S
K
Q
L
V
S
A
P
G
A
I
L
K
Site 158
S1785
V
K
L
R
L
Q
V
S
L
K
D
Y
I
N
Y
Site 159
Y1789
L
Q
V
S
L
K
D
Y
I
N
Y
I
L
K
K
Site 160
S1808
Q
E
M
M
V
K
D
S
R
T
E
E
E
R
G
Site 161
T1810
M
M
V
K
D
S
R
T
E
E
E
R
G
N
A
Site 162
S1826
D
L
L
K
L
V
M
S
F
P
K
M
E
E
T
Site 163
S1836
K
M
E
E
T
T
K
S
H
V
T
E
V
A
A
Site 164
T1839
E
T
T
K
S
H
V
T
E
V
A
A
H
L
T
Site 165
T1846
T
E
V
A
A
H
L
T
D
L
F
K
Q
S
L
Site 166
S1852
L
T
D
L
F
K
Q
S
L
A
T
P
P
K
C
Site 167
T1855
L
F
K
Q
S
L
A
T
P
P
K
C
P
P
D
Site 168
T1863
P
P
K
C
P
P
D
T
F
G
K
D
F
F
E
Site 169
T1872
G
K
D
F
F
E
K
T
W
R
H
T
A
S
S
Site 170
T1876
F
E
K
T
W
R
H
T
A
S
S
K
R
W
K
Site 171
S1878
K
T
W
R
H
T
A
S
S
K
R
W
K
E
K
Site 172
T1889
W
K
E
K
I
D
K
T
R
K
E
I
E
T
T
Site 173
T1895
K
T
R
K
E
I
E
T
T
Q
N
Y
L
M
D
Site 174
T1896
T
R
K
E
I
E
T
T
Q
N
Y
L
M
D
I
Site 175
Y1899
E
I
E
T
T
Q
N
Y
L
M
D
I
K
N
R
Site 176
Y1920
K
S
E
L
N
Q
L
Y
Q
S
Q
Y
N
H
L
Site 177
S1922
E
L
N
Q
L
Y
Q
S
Q
Y
N
H
L
D
S
Site 178
Y1924
N
Q
L
Y
Q
S
Q
Y
N
H
L
D
S
L
S
Site 179
S1929
S
Q
Y
N
H
L
D
S
L
S
K
K
L
P
S
Site 180
S1931
Y
N
H
L
D
S
L
S
K
K
L
P
S
F
T
Site 181
S1936
S
L
S
K
K
L
P
S
F
T
K
K
N
E
D
Site 182
S1953
E
T
A
V
Q
D
T
S
D
L
N
L
D
F
K
Site 183
S1965
D
F
K
P
H
K
V
S
E
Q
K
S
S
S
V
Site 184
S1969
H
K
V
S
E
Q
K
S
S
S
V
P
S
L
P
Site 185
S1970
K
V
S
E
Q
K
S
S
S
V
P
S
L
P
K
Site 186
S1971
V
S
E
Q
K
S
S
S
V
P
S
L
P
K
P
Site 187
S1974
Q
K
S
S
S
V
P
S
L
P
K
P
E
I
S
Site 188
S1981
S
L
P
K
P
E
I
S
A
D
K
K
D
F
T
Site 189
T1988
S
A
D
K
K
D
F
T
A
Q
N
Q
T
E
N
Site 190
T1997
Q
N
Q
T
E
N
L
T
K
S
P
E
E
A
E
Site 191
S1999
Q
T
E
N
L
T
K
S
P
E
E
A
E
S
Y
Site 192
S2005
K
S
P
E
E
A
E
S
Y
E
P
V
K
I
P
Site 193
Y2006
S
P
E
E
A
E
S
Y
E
P
V
K
I
P
T
Site 194
Y2034
E
K
V
K
L
P
H
Y
L
L
S
S
K
P
K
Site 195
S2037
K
L
P
H
Y
L
L
S
S
K
P
K
S
Q
P
Site 196
S2038
L
P
H
Y
L
L
S
S
K
P
K
S
Q
P
L
Site 197
S2042
L
L
S
S
K
P
K
S
Q
P
L
A
K
V
Q
Site 198
S2051
P
L
A
K
V
Q
D
S
V
G
G
K
V
N
T
Site 199
S2063
V
N
T
S
S
V
A
S
A
A
I
N
N
A
K
Site 200
Y2094
V
L
K
E
G
H
T
Y
A
T
V
V
K
L
K
Site 201
T2096
K
E
G
H
T
Y
A
T
V
V
K
L
K
N
V
Site 202
S2118
K
V
K
Q
P
P
P
S
T
G
L
K
V
T
Y
Site 203
T2119
V
K
Q
P
P
P
S
T
G
L
K
V
T
Y
K
Site 204
T2124
P
S
T
G
L
K
V
T
Y
K
P
G
P
V
A
Site 205
S2155
G
E
D
G
A
K
G
S
A
H
I
S
H
N
I
Site 206
S2205
N
P
M
V
Q
R
T
S
T
I
Y
S
S
T
L
Site 207
T2206
P
M
V
Q
R
T
S
T
I
Y
S
S
T
L
G
Site 208
Y2208
V
Q
R
T
S
T
I
Y
S
S
T
L
G
V
F
Site 209
S2209
Q
R
T
S
T
I
Y
S
S
T
L
G
V
F
M
Site 210
S2217
S
T
L
G
V
F
M
S
R
K
V
S
P
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation