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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAOX
Full Name:
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Alias:
Polyamine oxidase
Type:
Mass (Da):
70290
Number AA:
649
UniProt ID:
Q6QHF9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
S
T
G
S
V
G
E
A
P
G
G
Site 2
S36
A
Q
R
L
C
G
H
S
A
F
P
H
L
R
V
Site 3
T47
H
L
R
V
L
E
A
T
A
R
A
G
G
R
I
Site 4
S56
R
A
G
G
R
I
R
S
E
R
C
F
G
G
V
Site 5
S96
L
L
G
E
K
E
L
S
Q
E
N
Q
L
V
E
Site 6
S114
H
V
G
L
P
S
V
S
Y
A
S
S
G
T
S
Site 7
S118
P
S
V
S
Y
A
S
S
G
T
S
V
S
L
Q
Site 8
T150
E
F
L
H
A
A
E
T
P
V
P
S
V
G
E
Site 9
S154
A
A
E
T
P
V
P
S
V
G
E
Y
L
K
K
Site 10
Y158
P
V
P
S
V
G
E
Y
L
K
K
E
I
G
Q
Site 11
S256
P
S
V
S
Y
A
S
S
G
A
S
V
S
L
Q
Site 12
T314
G
W
T
E
D
E
E
T
R
K
L
K
L
A
V
Site 13
T358
V
L
P
G
L
D
C
T
F
S
K
G
Y
Q
G
Site 14
S360
P
G
L
D
C
T
F
S
K
G
Y
Q
G
L
T
Site 15
S407
P
G
E
T
F
P
V
S
V
E
C
E
D
G
D
Site 16
T436
F
L
R
E
H
L
D
T
F
F
D
P
P
L
P
Site 17
S485
Q
L
V
W
E
D
T
S
P
L
E
D
A
A
P
Site 18
T531
L
E
S
E
F
M
E
T
L
S
D
E
E
V
L
Site 19
T549
T
Q
V
L
R
R
V
T
G
N
P
R
L
P
A
Site 20
S559
P
R
L
P
A
P
K
S
V
L
R
S
R
W
H
Site 21
S563
A
P
K
S
V
L
R
S
R
W
H
S
A
P
Y
Site 22
S567
V
L
R
S
R
W
H
S
A
P
Y
T
R
G
S
Site 23
Y570
S
R
W
H
S
A
P
Y
T
R
G
S
Y
S
Y
Site 24
T571
R
W
H
S
A
P
Y
T
R
G
S
Y
S
Y
V
Site 25
S574
S
A
P
Y
T
R
G
S
Y
S
Y
V
A
V
G
Site 26
Y575
A
P
Y
T
R
G
S
Y
S
Y
V
A
V
G
S
Site 27
S576
P
Y
T
R
G
S
Y
S
Y
V
A
V
G
S
T
Site 28
Y577
Y
T
R
G
S
Y
S
Y
V
A
V
G
S
T
G
Site 29
T615
A
G
E
A
T
H
R
T
F
Y
S
T
T
H
G
Site 30
Y617
E
A
T
H
R
T
F
Y
S
T
T
H
G
A
L
Site 31
T619
T
H
R
T
F
Y
S
T
T
H
G
A
L
L
S
Site 32
S626
T
T
H
G
A
L
L
S
G
W
R
E
A
D
R
Site 33
S636
R
E
A
D
R
L
L
S
L
W
A
P
Q
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation