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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR133
Full Name:
Probable G-protein coupled receptor 133
Alias:
G-protein coupled receptor PGR25
Type:
Mass (Da):
96530
Number AA:
874
UniProt ID:
Q6QNK2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
N
F
Q
V
R
G
V
Y
S
R
S
Q
D
H
P
Site 2
S30
V
R
G
V
Y
S
R
S
Q
D
H
P
G
F
Q
Site 3
Y45
V
L
A
S
A
S
H
Y
W
P
L
E
N
V
D
Site 4
T60
G
I
H
E
L
Q
D
T
T
G
D
I
V
E
G
Site 5
Y74
G
K
V
N
K
G
I
Y
L
K
E
E
K
G
V
Site 6
T82
L
K
E
E
K
G
V
T
L
L
Y
Y
G
R
Y
Site 7
Y85
E
K
G
V
T
L
L
Y
Y
G
R
Y
N
S
S
Site 8
Y86
K
G
V
T
L
L
Y
Y
G
R
Y
N
S
S
C
Site 9
Y89
T
L
L
Y
Y
G
R
Y
N
S
S
C
I
S
K
Site 10
S91
L
Y
Y
G
R
Y
N
S
S
C
I
S
K
P
E
Site 11
S92
Y
Y
G
R
Y
N
S
S
C
I
S
K
P
E
Q
Site 12
S95
R
Y
N
S
S
C
I
S
K
P
E
Q
C
G
P
Site 13
S108
G
P
E
G
V
T
F
S
F
F
W
K
T
Q
G
Site 14
T113
T
F
S
F
F
W
K
T
Q
G
E
Q
S
R
P
Site 15
S118
W
K
T
Q
G
E
Q
S
R
P
I
P
S
A
Y
Site 16
S138
S
N
G
F
K
V
C
S
S
G
G
R
G
S
V
Site 17
S139
N
G
F
K
V
C
S
S
G
G
R
G
S
V
E
Site 18
S144
C
S
S
G
G
R
G
S
V
E
L
Y
T
R
D
Site 19
Y148
G
R
G
S
V
E
L
Y
T
R
D
N
S
M
T
Site 20
T149
R
G
S
V
E
L
Y
T
R
D
N
S
M
T
W
Site 21
S153
E
L
Y
T
R
D
N
S
M
T
W
E
A
S
F
Site 22
T155
Y
T
R
D
N
S
M
T
W
E
A
S
F
S
P
Site 23
S159
N
S
M
T
W
E
A
S
F
S
P
P
G
P
Y
Site 24
S161
M
T
W
E
A
S
F
S
P
P
G
P
Y
W
T
Site 25
Y166
S
F
S
P
P
G
P
Y
W
T
H
V
L
F
T
Site 26
Y183
S
K
E
G
L
K
V
Y
V
N
G
T
L
S
T
Site 27
T187
L
K
V
Y
V
N
G
T
L
S
T
S
D
P
S
Site 28
S189
V
Y
V
N
G
T
L
S
T
S
D
P
S
G
K
Site 29
T190
Y
V
N
G
T
L
S
T
S
D
P
S
G
K
V
Site 30
S191
V
N
G
T
L
S
T
S
D
P
S
G
K
V
S
Site 31
S194
T
L
S
T
S
D
P
S
G
K
V
S
R
D
Y
Site 32
S198
S
D
P
S
G
K
V
S
R
D
Y
G
E
S
N
Site 33
Y201
S
G
K
V
S
R
D
Y
G
E
S
N
V
N
L
Site 34
S204
V
S
R
D
Y
G
E
S
N
V
N
L
V
I
G
Site 35
T284
H
P
I
I
T
N
L
T
E
E
R
K
T
F
Q
Site 36
T289
N
L
T
E
E
R
K
T
F
Q
S
P
G
V
I
Site 37
S292
E
E
R
K
T
F
Q
S
P
G
V
I
L
S
Y
Site 38
S304
L
S
Y
L
Q
N
V
S
L
S
L
P
S
K
S
Site 39
S306
Y
L
Q
N
V
S
L
S
L
P
S
K
S
L
S
Site 40
S309
N
V
S
L
S
L
P
S
K
S
L
S
E
Q
T
Site 41
S311
S
L
S
L
P
S
K
S
L
S
E
Q
T
A
L
Site 42
S313
S
L
P
S
K
S
L
S
E
Q
T
A
L
N
L
Site 43
S363
T
V
M
G
H
V
S
S
N
L
H
G
S
T
P
Site 44
S368
V
S
S
N
L
H
G
S
T
P
Q
V
T
V
E
Site 45
T369
S
S
N
L
H
G
S
T
P
Q
V
T
V
E
G
Site 46
T373
H
G
S
T
P
Q
V
T
V
E
G
S
S
A
M
Site 47
T392
V
A
K
I
L
P
K
T
V
N
S
S
H
Y
R
Site 48
S396
L
P
K
T
V
N
S
S
H
Y
R
F
P
A
H
Site 49
Y398
K
T
V
N
S
S
H
Y
R
F
P
A
H
G
Q
Site 50
S406
R
F
P
A
H
G
Q
S
F
I
Q
I
P
H
E
Site 51
S468
H
L
I
S
L
E
V
S
P
P
P
T
L
S
Q
Site 52
T472
L
E
V
S
P
P
P
T
L
S
Q
N
L
S
G
Site 53
S474
V
S
P
P
P
T
L
S
Q
N
L
S
G
S
P
Site 54
T492
V
H
L
K
H
R
L
T
R
K
Q
H
S
E
A
Site 55
S497
R
L
T
R
K
Q
H
S
E
A
T
N
S
S
N
Site 56
S502
Q
H
S
E
A
T
N
S
S
N
R
V
F
V
Y
Site 57
S523
S
S
G
E
G
V
W
S
N
H
G
C
A
L
T
Site 58
T530
S
N
H
G
C
A
L
T
R
G
N
L
T
Y
S
Site 59
Y536
L
T
R
G
N
L
T
Y
S
V
C
R
C
T
H
Site 60
T596
A
V
L
S
S
V
S
T
I
R
N
Q
R
Y
H
Site 61
Y602
S
T
I
R
N
Q
R
Y
H
I
H
A
N
L
S
Site 62
T629
S
F
R
L
E
P
G
T
T
P
C
Q
V
M
A
Site 63
S670
K
V
F
G
S
E
D
S
K
H
R
Y
Y
Y
G
Site 64
Y674
S
E
D
S
K
H
R
Y
Y
Y
G
M
G
W
G
Site 65
Y675
E
D
S
K
H
R
Y
Y
Y
G
M
G
W
G
F
Site 66
Y676
D
S
K
H
R
Y
Y
Y
G
M
G
W
G
F
P
Site 67
S697
S
L
S
F
A
M
D
S
Y
G
T
S
N
N
C
Site 68
Y698
L
S
F
A
M
D
S
Y
G
T
S
N
N
C
W
Site 69
Y746
S
Q
I
S
A
D
N
Y
K
I
H
G
D
P
S
Site 70
S753
Y
K
I
H
G
D
P
S
A
F
K
L
T
A
K
Site 71
T821
R
A
A
F
K
H
K
T
K
V
W
S
L
T
S
Site 72
S825
K
H
K
T
K
V
W
S
L
T
S
S
S
A
R
Site 73
T827
K
T
K
V
W
S
L
T
S
S
S
A
R
T
S
Site 74
S828
T
K
V
W
S
L
T
S
S
S
A
R
T
S
N
Site 75
S829
K
V
W
S
L
T
S
S
S
A
R
T
S
N
A
Site 76
S830
V
W
S
L
T
S
S
S
A
R
T
S
N
A
K
Site 77
T833
L
T
S
S
S
A
R
T
S
N
A
K
P
F
H
Site 78
S834
T
S
S
S
A
R
T
S
N
A
K
P
F
H
S
Site 79
S841
S
N
A
K
P
F
H
S
D
L
M
N
G
T
R
Site 80
S853
G
T
R
P
G
M
A
S
T
K
L
S
P
W
D
Site 81
S857
G
M
A
S
T
K
L
S
P
W
D
K
S
S
H
Site 82
S862
K
L
S
P
W
D
K
S
S
H
S
A
H
R
V
Site 83
S863
L
S
P
W
D
K
S
S
H
S
A
H
R
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation