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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POTEE
Full Name:
POTE ankyrin domain family member E
Alias:
A26C1; A26C1A; A26CA; Cancer/testis antigen family 104, member 2; CT104.2; POTE ankyrin domain family, member E; POTE2; POTE-2; POTE2gamma; Prostate, ovary, testis-expressed protein on chromosome 2
Type:
Unknown function
Mass (Da):
121363
Number AA:
1075
UniProt ID:
Q6S8J3
International Prot ID:
IPI00479743
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
D
S
M
P
A
A
S
S
V
K
K
P
F
G
Site 2
S13
D
S
M
P
A
A
S
S
V
K
K
P
F
G
L
Site 3
S41
C
Y
R
E
S
G
K
S
N
V
G
T
S
G
D
Site 4
T45
S
G
K
S
N
V
G
T
S
G
D
H
D
D
S
Site 5
S52
T
S
G
D
H
D
D
S
A
M
K
T
L
R
S
Site 6
T56
H
D
D
S
A
M
K
T
L
R
S
K
M
G
K
Site 7
S78
C
C
R
G
S
G
K
S
N
V
G
A
S
G
D
Site 8
S89
A
S
G
D
H
D
D
S
A
M
K
T
L
R
N
Site 9
T93
H
D
D
S
A
M
K
T
L
R
N
K
M
G
K
Site 10
S112
C
F
P
C
C
R
G
S
G
K
S
K
V
G
A
Site 11
S115
C
C
R
G
S
G
K
S
K
V
G
A
W
G
D
Site 12
Y123
K
V
G
A
W
G
D
Y
D
D
S
A
F
M
E
Site 13
Y133
S
A
F
M
E
P
R
Y
H
V
R
G
E
D
L
Site 14
T164
L
I
V
M
L
R
D
T
D
V
N
K
K
D
K
Site 15
T175
K
K
D
K
Q
K
R
T
A
L
H
L
A
S
A
Site 16
Y238
D
P
N
I
P
D
E
Y
G
N
T
T
L
H
Y
Site 17
Y245
Y
G
N
T
T
L
H
Y
A
I
Y
N
E
D
K
Site 18
Y248
T
T
L
H
Y
A
I
Y
N
E
D
K
L
M
A
Site 19
S267
L
Y
G
A
D
I
E
S
K
N
K
H
G
L
T
Site 20
T274
S
K
N
K
H
G
L
T
P
L
L
L
G
V
H
Site 21
S332
L
E
Q
N
I
D
V
S
S
Q
D
L
S
G
Q
Site 22
S333
E
Q
N
I
D
V
S
S
Q
D
L
S
G
Q
T
Site 23
S337
D
V
S
S
Q
D
L
S
G
Q
T
A
R
E
Y
Site 24
Y344
S
G
Q
T
A
R
E
Y
A
V
S
S
H
H
H
Site 25
Y360
I
C
Q
L
L
S
D
Y
K
E
K
Q
M
L
K
Site 26
S373
L
K
I
S
S
E
N
S
N
P
E
Q
E
L
K
Site 27
T382
P
E
Q
E
L
K
L
T
S
E
E
E
S
Q
R
Site 28
S383
E
Q
E
L
K
L
T
S
E
E
E
S
Q
R
F
Site 29
S387
K
L
T
S
E
E
E
S
Q
R
F
K
G
S
E
Site 30
S396
R
F
K
G
S
E
N
S
Q
P
E
K
M
S
Q
Site 31
S402
N
S
Q
P
E
K
M
S
Q
E
L
E
I
N
K
Site 32
S452
G
L
I
P
Q
R
K
S
R
T
P
E
N
Q
Q
Site 33
T454
I
P
Q
R
K
S
R
T
P
E
N
Q
Q
F
P
Site 34
Y468
P
D
N
E
S
E
E
Y
H
R
I
C
E
L
L
Site 35
Y478
I
C
E
L
L
S
D
Y
K
E
K
Q
M
P
K
Site 36
Y486
K
E
K
Q
M
P
K
Y
S
S
E
N
S
N
P
Site 37
S487
E
K
Q
M
P
K
Y
S
S
E
N
S
N
P
E
Site 38
S488
K
Q
M
P
K
Y
S
S
E
N
S
N
P
E
Q
Site 39
S491
P
K
Y
S
S
E
N
S
N
P
E
Q
D
L
K
Site 40
S501
E
Q
D
L
K
L
T
S
E
E
E
S
Q
R
L
Site 41
S505
K
L
T
S
E
E
E
S
Q
R
L
K
G
S
E
Site 42
S511
E
S
Q
R
L
K
G
S
E
N
G
Q
P
E
K
Site 43
S520
N
G
Q
P
E
K
R
S
Q
E
P
E
I
N
K
Site 44
T548
E
M
K
K
H
G
S
T
H
V
G
F
P
E
N
Site 45
S575
G
L
I
P
P
R
K
S
R
T
P
E
S
Q
Q
Site 46
T577
I
P
P
R
K
S
R
T
P
E
S
Q
Q
F
P
Site 47
S580
R
K
S
R
T
P
E
S
Q
Q
F
P
D
T
E
Site 48
T586
E
S
Q
Q
F
P
D
T
E
N
E
E
Y
H
S
Site 49
Y591
P
D
T
E
N
E
E
Y
H
S
D
E
Q
N
D
Site 50
S593
T
E
N
E
E
Y
H
S
D
E
Q
N
D
T
Q
Site 51
T599
H
S
D
E
Q
N
D
T
Q
K
Q
F
C
E
E
Site 52
S632
E
V
V
E
K
M
N
S
E
L
S
L
S
C
K
Site 53
S635
E
K
M
N
S
E
L
S
L
S
C
K
K
E
K
Site 54
S637
M
N
S
E
L
S
L
S
C
K
K
E
K
D
V
Site 55
S649
K
D
V
L
H
E
N
S
T
L
R
E
E
I
A
Site 56
T650
D
V
L
H
E
N
S
T
L
R
E
E
I
A
M
Site 57
T664
M
L
R
L
E
L
D
T
M
K
H
Q
S
Q
L
Site 58
S669
L
D
T
M
K
H
Q
S
Q
L
R
E
K
K
Y
Site 59
Y676
S
Q
L
R
E
K
K
Y
L
E
D
I
E
S
V
Site 60
S682
K
Y
L
E
D
I
E
S
V
K
K
K
N
D
N
Site 61
T705
E
L
T
M
D
D
D
T
A
V
L
V
I
D
N
Site 62
S733
A
P
R
A
V
F
P
S
I
V
G
R
P
R
Q
Site 63
S752
G
G
M
H
Q
K
E
S
Y
V
G
K
E
A
Q
Site 64
Y753
G
M
H
Q
K
E
S
Y
V
G
K
E
A
Q
S
Site 65
S760
Y
V
G
K
E
A
Q
S
K
R
G
I
L
T
L
Site 66
T766
Q
S
K
R
G
I
L
T
L
K
Y
P
M
E
H
Site 67
T789
M
E
K
I
W
H
H
T
F
Y
N
E
L
R
V
Site 68
Y791
K
I
W
H
H
T
F
Y
N
E
L
R
V
A
P
Site 69
T806
E
E
H
P
I
L
L
T
E
A
P
L
N
P
K
Site 70
Y843
I
Q
A
V
P
S
L
Y
T
S
G
R
T
T
G
Site 71
T849
L
Y
T
S
G
R
T
T
G
I
V
M
D
S
G
Site 72
S855
T
T
G
I
V
M
D
S
G
D
G
V
T
H
T
Site 73
T862
S
G
D
G
V
T
H
T
V
P
I
Y
E
G
N
Site 74
Y866
V
T
H
T
V
P
I
Y
E
G
N
A
L
P
H
Site 75
T875
G
N
A
L
P
H
A
T
L
R
L
D
L
A
G
Site 76
Y888
A
G
R
E
L
P
D
Y
L
M
K
I
L
T
E
Site 77
T894
D
Y
L
M
K
I
L
T
E
R
G
Y
R
F
T
Site 78
Y898
K
I
L
T
E
R
G
Y
R
F
T
T
M
A
E
Site 79
T901
T
E
R
G
Y
R
F
T
T
M
A
E
R
E
I
Site 80
T902
E
R
G
Y
R
F
T
T
M
A
E
R
E
I
V
Site 81
Y918
D
I
K
E
K
L
C
Y
V
A
L
D
F
E
Q
Site 82
T929
D
F
E
Q
E
M
A
T
A
A
S
S
S
S
L
Site 83
S933
E
M
A
T
A
A
S
S
S
S
L
E
K
S
Y
Site 84
S935
A
T
A
A
S
S
S
S
L
E
K
S
Y
E
L
Site 85
S939
S
S
S
S
L
E
K
S
Y
E
L
P
D
G
Q
Site 86
Y940
S
S
S
L
E
K
S
Y
E
L
P
D
G
Q
V
Site 87
T949
L
P
D
G
Q
V
I
T
I
G
N
E
R
F
R
Site 88
T978
S
C
G
I
H
E
T
T
F
N
S
I
M
K
S
Site 89
S985
T
F
N
S
I
M
K
S
D
V
D
I
R
K
D
Site 90
Y994
V
D
I
R
K
D
L
Y
T
N
T
V
L
S
G
Site 91
T995
D
I
R
K
D
L
Y
T
N
T
V
L
S
G
G
Site 92
T997
R
K
D
L
Y
T
N
T
V
L
S
G
G
T
T
Site 93
Y1006
L
S
G
G
T
T
M
Y
P
G
M
A
H
R
M
Site 94
Y1037
I
A
P
P
K
R
K
Y
S
V
W
V
G
G
S
Site 95
S1038
A
P
P
K
R
K
Y
S
V
W
V
G
G
S
I
Site 96
Y1062
M
W
I
S
K
Q
E
Y
D
E
S
G
P
S
I
Site 97
S1065
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Site 98
S1068
E
Y
D
E
S
G
P
S
I
V
H
R
K
C
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation