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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CANP
Full Name:
Protein FAM111B
Alias:
F111B; FAM111B; Family with sequence similarity 111, member B; LOC374393; Protein FAM111B
Type:
Unknown function
Mass (Da):
84674
Number AA:
734
UniProt ID:
Q6SJ93
International Prot ID:
IPI00375836
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
N
S
M
K
T
E
E
N
K
Site 2
T6
_
_
M
N
S
M
K
T
E
E
N
K
S
F
S
Site 3
S11
M
K
T
E
E
N
K
S
F
S
A
M
E
D
D
Site 4
T29
R
P
E
V
S
K
D
T
V
M
K
Q
T
H
A
Site 5
T38
M
K
Q
T
H
A
D
T
P
V
D
H
C
L
S
Site 6
S45
T
P
V
D
H
C
L
S
G
I
R
K
C
S
S
Site 7
S51
L
S
G
I
R
K
C
S
S
T
F
K
L
K
S
Site 8
S52
S
G
I
R
K
C
S
S
T
F
K
L
K
S
E
Site 9
T53
G
I
R
K
C
S
S
T
F
K
L
K
S
E
V
Site 10
S58
S
S
T
F
K
L
K
S
E
V
N
K
H
E
T
Site 11
T84
K
E
C
C
F
T
F
T
L
N
G
N
S
R
K
Site 12
S95
N
S
R
K
L
D
R
S
V
F
T
A
Y
G
K
Site 13
Y100
D
R
S
V
F
T
A
Y
G
K
P
S
E
S
I
Site 14
S106
A
Y
G
K
P
S
E
S
I
Y
S
A
L
S
A
Site 15
Y108
G
K
P
S
E
S
I
Y
S
A
L
S
A
N
D
Site 16
S109
K
P
S
E
S
I
Y
S
A
L
S
A
N
D
Y
Site 17
S112
E
S
I
Y
S
A
L
S
A
N
D
Y
F
S
E
Site 18
Y116
S
A
L
S
A
N
D
Y
F
S
E
R
I
K
N
Site 19
S118
L
S
A
N
D
Y
F
S
E
R
I
K
N
Q
F
Site 20
S152
M
P
L
K
C
L
P
S
D
S
H
F
K
I
T
Site 21
S154
L
K
C
L
P
S
D
S
H
F
K
I
T
F
G
Site 22
T159
S
D
S
H
F
K
I
T
F
G
Q
R
K
S
S
Site 23
S165
I
T
F
G
Q
R
K
S
S
K
E
D
G
H
I
Site 24
S166
T
F
G
Q
R
K
S
S
K
E
D
G
H
I
L
Site 25
S233
C
K
D
G
R
F
R
S
D
I
G
E
F
E
W
Site 26
Y250
K
E
G
H
K
K
I
Y
G
K
Q
S
M
V
D
Site 27
S254
K
K
I
Y
G
K
Q
S
M
V
D
E
V
S
G
Site 28
S269
K
V
L
E
M
D
I
S
K
K
K
A
L
Q
Q
Site 29
S288
K
K
I
K
Q
N
E
S
A
T
D
E
I
N
H
Site 30
S297
T
D
E
I
N
H
Q
S
L
I
Q
S
K
K
K
Site 31
S301
N
H
Q
S
L
I
Q
S
K
K
K
V
H
K
P
Site 32
T314
K
P
K
K
D
G
E
T
K
D
V
E
H
S
R
Site 33
S331
I
L
P
P
Q
D
L
S
H
Y
I
K
D
K
T
Site 34
Y333
P
P
Q
D
L
S
H
Y
I
K
D
K
T
R
Q
Site 35
T338
S
H
Y
I
K
D
K
T
R
Q
T
I
P
R
I
Site 36
T341
I
K
D
K
T
R
Q
T
I
P
R
I
R
N
Y
Site 37
Y348
T
I
P
R
I
R
N
Y
Y
F
C
S
L
P
R
Site 38
Y349
I
P
R
I
R
N
Y
Y
F
C
S
L
P
R
K
Site 39
S352
I
R
N
Y
Y
F
C
S
L
P
R
K
Y
R
Q
Site 40
Y357
F
C
S
L
P
R
K
Y
R
Q
I
N
S
Q
V
Site 41
S362
R
K
Y
R
Q
I
N
S
Q
V
R
R
R
P
H
Site 42
Y374
R
P
H
L
G
R
R
Y
A
I
N
L
D
V
Q
Site 43
Y402
N
E
A
I
M
H
Q
Y
P
N
F
K
E
E
A
Site 44
Y415
E
A
Q
W
V
R
K
Y
F
R
E
E
Q
K
R
Site 45
S426
E
Q
K
R
M
N
L
S
P
A
K
Q
F
N
I
Site 46
Y434
P
A
K
Q
F
N
I
Y
K
K
D
F
G
K
M
Site 47
T442
K
K
D
F
G
K
M
T
A
N
S
V
S
V
A
Site 48
T455
V
A
T
C
E
Q
L
T
Y
Y
S
K
S
V
G
Site 49
Y456
A
T
C
E
Q
L
T
Y
Y
S
K
S
V
G
F
Site 50
Y457
T
C
E
Q
L
T
Y
Y
S
K
S
V
G
F
M
Site 51
S503
V
G
K
N
T
H
P
S
L
W
P
D
I
I
S
Site 52
Y545
V
S
N
E
N
L
D
Y
A
I
L
K
L
K
E
Site 53
S566
P
G
L
W
R
Q
I
S
P
Q
P
S
T
G
L
Site 54
Y575
Q
P
S
T
G
L
I
Y
L
I
G
H
P
E
G
Site 55
T591
I
K
K
I
D
G
C
T
V
I
P
L
N
E
R
Site 56
Y602
L
N
E
R
L
K
K
Y
P
N
D
C
Q
D
G
Site 57
Y614
Q
D
G
L
V
D
L
Y
D
T
T
S
N
V
Y
Site 58
T636
F
L
S
E
V
W
N
T
H
T
L
S
Y
D
T
Site 59
T638
S
E
V
W
N
T
H
T
L
S
Y
D
T
C
F
Site 60
T643
T
H
T
L
S
Y
D
T
C
F
S
D
G
S
S
Site 61
S646
L
S
Y
D
T
C
F
S
D
G
S
S
G
S
P
Site 62
S649
D
T
C
F
S
D
G
S
S
G
S
P
V
F
N
Site 63
S650
T
C
F
S
D
G
S
S
G
S
P
V
F
N
A
Site 64
S652
F
S
D
G
S
S
G
S
P
V
F
N
A
S
G
Site 65
Y671
L
H
T
F
G
L
F
Y
Q
R
G
F
N
V
H
Site 66
S700
D
I
K
K
T
N
E
S
L
Y
K
S
L
N
D
Site 67
Y702
K
K
T
N
E
S
L
Y
K
S
L
N
D
E
K
Site 68
S704
T
N
E
S
L
Y
K
S
L
N
D
E
K
L
E
Site 69
T712
L
N
D
E
K
L
E
T
Y
D
E
E
K
G
K
Site 70
Y713
N
D
E
K
L
E
T
Y
D
E
E
K
G
K
Q
Site 71
S723
E
K
G
K
Q
E
S
S
L
Q
D
H
Q
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation