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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBPL2
Full Name:
TATA box-binding protein-like protein 2
Alias:
TBP2; TRF3
Type:
Cytoplasm, Nucleus protein
Mass (Da):
41524
Number AA:
375
UniProt ID:
Q6SJ96
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0006367
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
L
L
A
P
R
L
P
S
Y
P
P
P
P
P
T
Site 2
Y21
L
A
P
R
L
P
S
Y
P
P
P
P
P
T
V
Site 3
T27
S
Y
P
P
P
P
P
T
V
G
L
R
S
M
E
Site 4
S32
P
P
T
V
G
L
R
S
M
E
Q
E
E
T
Y
Site 5
T38
R
S
M
E
Q
E
E
T
Y
L
E
L
Y
L
D
Site 6
Y39
S
M
E
Q
E
E
T
Y
L
E
L
Y
L
D
Q
Site 7
Y43
E
E
T
Y
L
E
L
Y
L
D
Q
C
A
A
Q
Site 8
S62
P
P
R
S
P
L
F
S
P
V
V
P
Y
D
M
Site 9
T79
L
N
A
S
N
P
D
T
A
F
N
S
N
P
E
Site 10
S83
N
P
D
T
A
F
N
S
N
P
E
V
K
E
T
Site 11
T90
S
N
P
E
V
K
E
T
S
G
D
F
S
S
V
Site 12
S91
N
P
E
V
K
E
T
S
G
D
F
S
S
V
D
Site 13
S95
K
E
T
S
G
D
F
S
S
V
D
L
S
F
L
Site 14
S96
E
T
S
G
D
F
S
S
V
D
L
S
F
L
P
Site 15
S100
D
F
S
S
V
D
L
S
F
L
P
D
E
V
T
Site 16
T107
S
F
L
P
D
E
V
T
Q
E
N
K
D
Q
P
Site 17
T121
P
V
I
S
K
H
E
T
E
E
N
S
E
S
Q
Site 18
S125
K
H
E
T
E
E
N
S
E
S
Q
S
P
Q
S
Site 19
S127
E
T
E
E
N
S
E
S
Q
S
P
Q
S
R
L
Site 20
S129
E
E
N
S
E
S
Q
S
P
Q
S
R
L
P
S
Site 21
S132
S
E
S
Q
S
P
Q
S
R
L
P
S
P
S
E
Site 22
S136
S
P
Q
S
R
L
P
S
P
S
E
Q
D
V
G
Site 23
S138
Q
S
R
L
P
S
P
S
E
Q
D
V
G
L
G
Site 24
S148
D
V
G
L
G
L
N
S
S
S
L
S
N
S
H
Site 25
S149
V
G
L
G
L
N
S
S
S
L
S
N
S
H
S
Site 26
S150
G
L
G
L
N
S
S
S
L
S
N
S
H
S
Q
Site 27
S152
G
L
N
S
S
S
L
S
N
S
H
S
Q
L
H
Site 28
S154
N
S
S
S
L
S
N
S
H
S
Q
L
H
P
G
Site 29
S156
S
S
L
S
N
S
H
S
Q
L
H
P
G
D
T
Site 30
T163
S
Q
L
H
P
G
D
T
D
S
V
Q
P
S
P
Site 31
S165
L
H
P
G
D
T
D
S
V
Q
P
S
P
E
K
Site 32
S169
D
T
D
S
V
Q
P
S
P
E
K
P
N
S
D
Site 33
S175
P
S
P
E
K
P
N
S
D
S
L
S
L
A
S
Site 34
S177
P
E
K
P
N
S
D
S
L
S
L
A
S
I
T
Site 35
S179
K
P
N
S
D
S
L
S
L
A
S
I
T
P
M
Site 36
T247
R
I
R
E
P
R
T
T
A
L
I
F
S
S
G
Site 37
T259
S
S
G
K
M
V
C
T
G
A
K
S
E
E
Q
Site 38
S263
M
V
C
T
G
A
K
S
E
E
Q
S
R
L
A
Site 39
S267
G
A
K
S
E
E
Q
S
R
L
A
A
R
K
Y
Site 40
Y274
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Site 41
T313
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Site 42
S319
L
T
H
Q
Q
F
S
S
Y
E
P
E
L
F
P
Site 43
Y359
A
K
E
R
S
E
I
Y
E
A
F
E
N
I
Y
Site 44
Y366
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation