KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SMARCD3
Full Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
Alias:
60 kDa BRG-1/Brm-associated factor C; 60 kDa BRG-1/Brm-associated factor subunit C; 60kDa BRG-1/Brm associated factor subunit c; BAF60C; BRG1-associated factor 60C; Chromatin remodeling complex BAF60C; CRACD3; HCG_1737498; Mammalian chromatin remodeling complex BRG1-associated factor 60C; Rsc6p; SMRD3; SWI/SNF complex 60 kDa C; SWI/SNF complex 60 kDa subunit C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, isoform 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like; Swp73-like protein
Type:
Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Mass (Da):
55016
Number AA:
483
UniProt ID:
Q6STE5
International Prot ID:
IPI00456146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005654
GO:0016514
Uniprot
OncoNet
Molecular Function:
GO:0003712
GO:0003713
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0003007
GO:0006139
GO:0006325
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
A
G
G
A
R
K
A
T
K
S
K
L
F
E
F
Site 2
S16
G
A
R
K
A
T
K
S
K
L
F
E
F
L
V
Site 3
S32
G
V
R
P
G
M
P
S
G
A
R
M
P
H
Q
Site 4
S48
A
P
M
G
P
P
G
S
P
Y
M
G
S
P
A
Site 5
Y50
M
G
P
P
G
S
P
Y
M
G
S
P
A
V
R
Site 6
S53
P
G
S
P
Y
M
G
S
P
A
V
R
P
G
L
Site 7
S79
A
A
P
P
P
G
Q
S
Q
A
Q
S
Q
G
Q
Site 8
S83
P
G
Q
S
Q
A
Q
S
Q
G
Q
P
V
P
T
Site 9
S97
T
A
P
A
R
S
R
S
A
K
R
R
K
M
A
Site 10
T135
F
E
R
K
L
D
Q
T
I
M
R
K
R
V
D
Site 11
Y160
Q
K
R
K
L
R
L
Y
I
S
N
T
F
N
P
Site 12
S162
R
K
L
R
L
Y
I
S
N
T
F
N
P
A
K
Site 13
T164
L
R
L
Y
I
S
N
T
F
N
P
A
K
P
D
Site 14
S175
A
K
P
D
A
E
D
S
D
G
S
I
A
S
W
Site 15
S178
D
A
E
D
S
D
G
S
I
A
S
W
E
L
R
Site 16
S181
D
S
D
G
S
I
A
S
W
E
L
R
V
E
G
Site 17
S195
G
K
L
L
D
D
P
S
K
Q
K
R
K
F
S
Site 18
S202
S
K
Q
K
R
K
F
S
S
F
F
K
S
L
V
Site 19
S203
K
Q
K
R
K
F
S
S
F
F
K
S
L
V
I
Site 20
Y217
I
E
L
D
K
D
L
Y
G
P
D
N
H
L
V
Site 21
T229
H
L
V
E
W
H
R
T
P
T
T
Q
E
T
D
Site 22
T231
V
E
W
H
R
T
P
T
T
Q
E
T
D
G
F
Site 23
T232
E
W
H
R
T
P
T
T
Q
E
T
D
G
F
Q
Site 24
Y258
T
L
L
L
M
L
D
Y
Q
P
P
Q
F
K
L
Site 25
T277
A
R
L
L
G
L
H
T
Q
S
R
S
A
I
V
Site 26
Y290
I
V
Q
A
L
W
Q
Y
V
K
T
N
R
L
Q
Site 27
T293
A
L
W
Q
Y
V
K
T
N
R
L
Q
D
S
H
Site 28
S299
K
T
N
R
L
Q
D
S
H
D
K
E
Y
I
N
Site 29
Y304
Q
D
S
H
D
K
E
Y
I
N
G
D
K
Y
F
Site 30
Y310
E
Y
I
N
G
D
K
Y
F
Q
Q
I
F
D
C
Site 31
T330
S
E
I
P
Q
R
L
T
A
L
L
L
P
P
D
Site 32
S346
I
V
I
N
H
V
I
S
V
D
P
S
D
Q
K
Site 33
S350
H
V
I
S
V
D
P
S
D
Q
K
K
T
A
C
Site 34
S373
E
P
L
K
G
Q
M
S
S
F
L
L
S
T
A
Site 35
S374
P
L
K
G
Q
M
S
S
F
L
L
S
T
A
N
Site 36
S378
Q
M
S
S
F
L
L
S
T
A
N
Q
Q
E
I
Site 37
S386
T
A
N
Q
Q
E
I
S
A
L
D
S
K
I
H
Site 38
S390
Q
E
I
S
A
L
D
S
K
I
H
E
T
I
E
Site 39
S398
K
I
H
E
T
I
E
S
I
N
Q
L
K
I
Q
Site 40
S411
I
Q
R
D
F
M
L
S
F
S
R
D
P
K
G
Site 41
S413
R
D
F
M
L
S
F
S
R
D
P
K
G
Y
V
Site 42
Y419
F
S
R
D
P
K
G
Y
V
Q
D
L
L
R
S
Site 43
S426
Y
V
Q
D
L
L
R
S
Q
S
R
D
L
K
V
Site 44
S428
Q
D
L
L
R
S
Q
S
R
D
L
K
V
M
T
Site 45
Y450
E
E
R
R
A
E
F
Y
H
Q
P
W
S
Q
E
Site 46
Y462
S
Q
E
A
V
S
R
Y
F
Y
C
K
I
Q
Q
Site 47
Y464
E
A
V
S
R
Y
F
Y
C
K
I
Q
Q
R
R
Site 48
S477
R
R
Q
E
L
E
Q
S
L
V
V
R
N
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation