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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRG2
Full Name:
Lipid phosphate phosphatase-related protein type 3
Alias:
LPPR3; PAP-2-like protein 2; Plasticity-related gene 2 protein
Type:
Phosphatase (non-protein); EC 3.1.3.4
Mass (Da):
76019
Number AA:
718
UniProt ID:
Q6T4P5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0008195
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y55
A
K
V
G
F
Q
C
Y
D
R
T
L
S
M
P
Site 2
T58
G
F
Q
C
Y
D
R
T
L
S
M
P
Y
V
E
Site 3
Y63
D
R
T
L
S
M
P
Y
V
E
T
N
E
E
L
Site 4
S115
G
P
A
G
A
E
G
S
I
N
A
G
G
C
N
Site 5
S125
A
G
G
C
N
F
N
S
F
L
R
R
T
V
R
Site 6
Y182
T
S
C
E
V
N
P
Y
I
T
Q
D
I
C
S
Site 7
S198
H
D
I
H
A
I
L
S
A
R
K
T
F
P
S
Site 8
T202
A
I
L
S
A
R
K
T
F
P
S
Q
H
A
T
Site 9
S205
S
A
R
K
T
F
P
S
Q
H
A
T
L
S
A
Site 10
S224
Y
V
S
M
Y
F
N
S
V
I
S
D
T
T
K
Site 11
T254
V
C
G
L
T
Q
I
T
Q
Y
R
S
H
P
V
Site 12
T307
K
D
A
L
R
A
L
T
Q
R
G
H
D
S
V
Site 13
S313
L
T
Q
R
G
H
D
S
V
Y
Q
Q
N
K
S
Site 14
Y315
Q
R
G
H
D
S
V
Y
Q
Q
N
K
S
V
S
Site 15
S320
S
V
Y
Q
Q
N
K
S
V
S
T
D
E
L
G
Site 16
S322
Y
Q
Q
N
K
S
V
S
T
D
E
L
G
P
P
Site 17
T344
R
P
V
A
R
E
K
T
S
L
G
S
L
K
R
Site 18
S345
P
V
A
R
E
K
T
S
L
G
S
L
K
R
A
Site 19
S348
R
E
K
T
S
L
G
S
L
K
R
A
S
V
D
Site 20
S353
L
G
S
L
K
R
A
S
V
D
V
D
L
L
A
Site 21
S363
V
D
L
L
A
P
R
S
P
M
A
K
E
N
M
Site 22
T372
M
A
K
E
N
M
V
T
F
S
H
T
L
P
R
Site 23
S374
K
E
N
M
V
T
F
S
H
T
L
P
R
A
S
Site 24
T376
N
M
V
T
F
S
H
T
L
P
R
A
S
A
P
Site 25
S381
S
H
T
L
P
R
A
S
A
P
S
L
D
D
P
Site 26
S384
L
P
R
A
S
A
P
S
L
D
D
P
A
R
R
Site 27
T394
D
P
A
R
R
H
M
T
I
H
V
P
L
D
A
Site 28
S402
I
H
V
P
L
D
A
S
R
S
K
Q
L
I
S
Site 29
S404
V
P
L
D
A
S
R
S
K
Q
L
I
S
E
W
Site 30
S409
S
R
S
K
Q
L
I
S
E
W
K
Q
K
S
L
Site 31
S415
I
S
E
W
K
Q
K
S
L
E
G
R
G
L
G
Site 32
S428
L
G
L
P
D
D
A
S
P
G
H
L
R
A
P
Site 33
S467
D
E
G
P
A
P
P
S
L
Y
P
T
V
Q
A
Site 34
Y469
G
P
A
P
P
S
L
Y
P
T
V
Q
A
R
P
Site 35
T471
A
P
P
S
L
Y
P
T
V
Q
A
R
P
G
L
Site 36
T503
I
P
E
E
G
A
Q
T
G
A
G
L
S
P
K
Site 37
S508
A
Q
T
G
A
G
L
S
P
K
S
G
A
G
V
Site 38
S511
G
A
G
L
S
P
K
S
G
A
G
V
R
A
K
Site 39
S526
W
L
M
M
A
E
K
S
G
A
A
V
A
N
P
Site 40
T556
P
G
P
K
A
A
E
T
A
S
S
S
S
A
S
Site 41
S558
P
K
A
A
E
T
A
S
S
S
S
A
S
S
D
Site 42
S559
K
A
A
E
T
A
S
S
S
S
A
S
S
D
S
Site 43
S560
A
A
E
T
A
S
S
S
S
A
S
S
D
S
S
Site 44
S561
A
E
T
A
S
S
S
S
A
S
S
D
S
S
Q
Site 45
S563
T
A
S
S
S
S
A
S
S
D
S
S
Q
Y
R
Site 46
S564
A
S
S
S
S
A
S
S
D
S
S
Q
Y
R
S
Site 47
S566
S
S
S
A
S
S
D
S
S
Q
Y
R
S
P
S
Site 48
S567
S
S
A
S
S
D
S
S
Q
Y
R
S
P
S
D
Site 49
Y569
A
S
S
D
S
S
Q
Y
R
S
P
S
D
R
D
Site 50
S571
S
D
S
S
Q
Y
R
S
P
S
D
R
D
S
A
Site 51
S573
S
S
Q
Y
R
S
P
S
D
R
D
S
A
S
I
Site 52
S577
R
S
P
S
D
R
D
S
A
S
I
V
T
I
D
Site 53
S579
P
S
D
R
D
S
A
S
I
V
T
I
D
A
H
Site 54
S596
H
H
P
V
V
H
L
S
A
G
G
A
P
W
E
Site 55
Y619
K
A
E
A
D
G
G
Y
E
L
G
D
L
A
R
Site 56
S638
G
A
K
P
P
G
V
S
P
G
S
S
V
S
D
Site 57
S641
P
P
G
V
S
P
G
S
S
V
S
D
V
D
Q
Site 58
S642
P
G
V
S
P
G
S
S
V
S
D
V
D
Q
E
Site 59
S644
V
S
P
G
S
S
V
S
D
V
D
Q
E
E
P
Site 60
S681
D
G
A
L
G
P
G
S
R
E
S
T
L
R
R
Site 61
S684
L
G
P
G
S
R
E
S
T
L
R
R
H
A
G
Site 62
T685
G
P
G
S
R
E
S
T
L
R
R
H
A
G
G
Site 63
Y707
A
E
A
E
A
E
G
Y
F
R
K
M
Q
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation