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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC4A10
Full Name:
Sodium-driven chloride bicarbonate exchanger
Alias:
NBCn2; NCBE; S4A10; Solute carrier family 4 member 10; Solute carrier family 4, sodium bicarbonate transporter, member 10
Type:
Mass (Da):
125946
Number AA:
1118
UniProt ID:
Q6U841
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005452
GO:0031402
GO:0015293
PhosphoSite+
KinaseNET
Biological Process:
GO:0015701
GO:0006821
GO:0006814
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
A
V
V
D
R
G
G
T
R
S
I
L
K
T
H
Site 2
S31
V
D
R
G
G
T
R
S
I
L
K
T
H
F
E
Site 3
T35
G
T
R
S
I
L
K
T
H
F
E
K
E
D
L
Site 4
T47
E
D
L
E
G
H
R
T
L
F
I
G
V
H
V
Site 5
S61
V
P
L
G
G
R
K
S
H
R
R
H
R
H
R
Site 6
S81
K
R
D
R
E
R
D
S
G
L
E
D
G
R
E
Site 7
S89
G
L
E
D
G
R
E
S
P
S
F
D
T
P
S
Site 8
S91
E
D
G
R
E
S
P
S
F
D
T
P
S
Q
R
Site 9
T94
R
E
S
P
S
F
D
T
P
S
Q
R
V
Q
F
Site 10
S96
S
P
S
F
D
T
P
S
Q
R
V
Q
F
I
L
Site 11
T137
E
D
A
E
W
R
E
T
A
R
W
L
K
F
E
Site 12
S155
E
D
G
G
E
R
W
S
K
P
Y
V
A
T
L
Site 13
Y158
G
E
R
W
S
K
P
Y
V
A
T
L
S
L
H
Site 14
T161
W
S
K
P
Y
V
A
T
L
S
L
H
S
L
F
Site 15
T230
H
Q
N
Q
K
K
L
T
N
R
I
P
I
V
R
Site 16
S238
N
R
I
P
I
V
R
S
F
A
D
I
G
K
K
Site 17
S247
A
D
I
G
K
K
Q
S
E
P
N
S
M
D
K
Site 18
S251
K
K
Q
S
E
P
N
S
M
D
K
N
A
G
Q
Site 19
S261
K
N
A
G
Q
V
V
S
P
Q
S
A
P
A
C
Site 20
S264
G
Q
V
V
S
P
Q
S
A
P
A
C
V
E
N
Site 21
S276
V
E
N
K
N
D
V
S
R
E
N
S
T
V
D
Site 22
S280
N
D
V
S
R
E
N
S
T
V
D
F
S
K
G
Site 23
T281
D
V
S
R
E
N
S
T
V
D
F
S
K
G
L
Site 24
S285
E
N
S
T
V
D
F
S
K
G
L
G
G
Q
Q
Site 25
S297
G
Q
Q
K
G
H
T
S
P
C
G
M
K
Q
R
Site 26
S353
V
V
A
F
V
R
L
S
P
A
V
L
L
Q
G
Site 27
T368
L
A
E
V
P
I
P
T
R
F
L
F
I
L
L
Site 28
Y384
P
L
G
K
G
Q
Q
Y
H
E
I
G
R
S
I
Site 29
S390
Q
Y
H
E
I
G
R
S
I
A
T
L
M
T
D
Site 30
Y405
E
V
F
H
D
V
A
Y
K
A
K
D
R
N
D
Site 31
S415
K
D
R
N
D
L
V
S
G
I
D
E
F
L
D
Site 32
T425
D
E
F
L
D
Q
V
T
V
L
P
P
G
E
W
Site 33
S435
P
P
G
E
W
D
P
S
I
R
I
E
P
P
K
Site 34
S446
E
P
P
K
N
V
P
S
Q
E
K
R
K
I
P
Site 35
T479
S
G
P
E
L
Q
R
T
G
R
I
F
G
G
L
Site 36
Y496
D
I
K
R
K
A
P
Y
F
W
S
D
F
R
D
Site 37
S540
E
A
T
E
G
R
I
S
A
I
E
S
L
F
G
Site 38
S589
F
C
K
E
Y
G
L
S
Y
L
S
L
R
A
S
Site 39
Y590
C
K
E
Y
G
L
S
Y
L
S
L
R
A
S
I
Site 40
Y619
D
A
S
S
L
V
C
Y
I
T
R
F
T
E
E
Site 41
S648
L
E
K
L
F
E
L
S
E
A
Y
P
I
N
M
Site 42
Y651
L
F
E
L
S
E
A
Y
P
I
N
M
H
N
D
Site 43
S686
T
L
K
E
W
R
E
S
N
I
S
A
S
D
I
Site 44
S689
E
W
R
E
S
N
I
S
A
S
D
I
I
W
E
Site 45
S691
R
E
S
N
I
S
A
S
D
I
I
W
E
N
L
Site 46
S705
L
T
V
S
E
C
K
S
L
H
G
E
Y
V
G
Site 47
Y710
C
K
S
L
H
G
E
Y
V
G
R
A
C
G
H
Site 48
T742
S
T
V
T
L
S
A
T
L
K
Q
F
K
T
S
Site 49
T748
A
T
L
K
Q
F
K
T
S
R
Y
F
P
T
K
Site 50
Y751
K
Q
F
K
T
S
R
Y
F
P
T
K
V
R
S
Site 51
T754
K
T
S
R
Y
F
P
T
K
V
R
S
I
V
S
Site 52
S783
D
Y
A
I
G
I
P
S
P
K
L
Q
V
P
S
Site 53
S790
S
P
K
L
Q
V
P
S
V
F
K
P
T
R
D
Site 54
T804
D
D
R
G
W
F
V
T
P
L
G
P
N
P
W
Site 55
S887
L
S
I
T
H
V
N
S
L
K
L
E
S
E
C
Site 56
S892
V
N
S
L
K
L
E
S
E
C
S
A
P
G
E
Site 57
S895
L
K
L
E
S
E
C
S
A
P
G
E
Q
P
K
Site 58
Y974
K
H
Q
P
D
F
I
Y
L
R
H
V
P
L
R
Site 59
S1033
L
F
T
K
R
E
L
S
W
L
D
D
L
M
P
Site 60
S1042
L
D
D
L
M
P
E
S
K
K
K
K
L
E
D
Site 61
S1057
A
E
K
E
E
E
Q
S
M
L
A
M
E
D
E
Site 62
T1066
L
A
M
E
D
E
G
T
V
Q
L
P
L
E
G
Site 63
S1080
G
H
Y
R
D
D
P
S
V
I
N
I
S
D
E
Site 64
S1085
D
P
S
V
I
N
I
S
D
E
M
S
K
T
A
Site 65
T1091
I
S
D
E
M
S
K
T
A
L
W
R
N
L
L
Site 66
T1100
L
W
R
N
L
L
I
T
A
D
N
S
K
D
K
Site 67
S1104
L
L
I
T
A
D
N
S
K
D
K
E
S
S
F
Site 68
S1109
D
N
S
K
D
K
E
S
S
F
P
S
K
S
S
Site 69
S1110
N
S
K
D
K
E
S
S
F
P
S
K
S
S
P
Site 70
S1113
D
K
E
S
S
F
P
S
K
S
S
P
S
_
_
Site 71
S1115
E
S
S
F
P
S
K
S
S
P
S
_
_
_
_
Site 72
S1116
S
S
F
P
S
K
S
S
P
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation