KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FIP1L1
Full Name:
Pre-mRNA 3'-end-processing factor FIP1
Alias:
DKFZp586K0717; Factor interacting with PAP; FIP1; FIP1 like 1; FIP1 like 1 (S. cerevisiae); FIP1-like 1; HFip1; Rearranged in hypereosinophilia; RHE
Type:
RNA processing
Mass (Da):
66526
Number AA:
594
UniProt ID:
Q6UN15
International Prot ID:
IPI00395337
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0003723
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006397
GO:0006396
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
G
E
V
E
R
L
V
S
E
L
S
G
G
T
G
Site 2
S14
E
R
L
V
S
E
L
S
G
G
T
G
G
D
E
Site 3
Y27
D
E
E
E
E
W
L
Y
G
G
P
W
D
V
H
Site 4
S37
P
W
D
V
H
V
H
S
D
L
A
K
D
L
D
Site 5
S57
R
P
E
E
E
N
A
S
A
N
P
P
S
G
I
Site 6
S62
N
A
S
A
N
P
P
S
G
I
E
D
E
T
A
Site 7
T68
P
S
G
I
E
D
E
T
A
E
N
G
V
P
K
Site 8
T79
G
V
P
K
P
K
V
T
E
T
E
D
D
S
D
Site 9
T81
P
K
P
K
V
T
E
T
E
D
D
S
D
S
D
Site 10
S85
V
T
E
T
E
D
D
S
D
S
D
S
D
D
D
Site 11
S87
E
T
E
D
D
S
D
S
D
S
D
D
D
E
D
Site 12
S89
E
D
D
S
D
S
D
S
D
D
D
E
D
D
V
Site 13
T99
D
E
D
D
V
H
V
T
I
G
D
I
K
T
G
Site 14
T105
V
T
I
G
D
I
K
T
G
A
P
Q
Y
G
S
Site 15
Y110
I
K
T
G
A
P
Q
Y
G
S
Y
G
T
A
P
Site 16
S112
T
G
A
P
Q
Y
G
S
Y
G
T
A
P
V
N
Site 17
Y113
G
A
P
Q
Y
G
S
Y
G
T
A
P
V
N
L
Site 18
T124
P
V
N
L
N
I
K
T
G
G
R
V
Y
G
T
Site 19
Y129
I
K
T
G
G
R
V
Y
G
T
T
G
T
K
V
Site 20
T132
G
G
R
V
Y
G
T
T
G
T
K
V
K
G
V
Site 21
S159
L
L
E
V
D
L
D
S
F
E
D
K
P
W
R
Site 22
S173
R
K
P
G
A
D
L
S
D
Y
F
N
Y
G
F
Site 23
Y175
P
G
A
D
L
S
D
Y
F
N
Y
G
F
N
E
Site 24
T217
K
I
T
A
E
D
C
T
M
E
V
T
P
G
A
Site 25
T221
E
D
C
T
M
E
V
T
P
G
A
E
I
Q
D
Site 26
T248
T
G
N
S
E
K
E
T
A
L
P
S
T
K
A
Site 27
T253
K
E
T
A
L
P
S
T
K
A
E
F
T
S
P
Site 28
T258
P
S
T
K
A
E
F
T
S
P
P
S
L
F
K
Site 29
S259
S
T
K
A
E
F
T
S
P
P
S
L
F
K
T
Site 30
S262
A
E
F
T
S
P
P
S
L
F
K
T
G
L
P
Site 31
T266
S
P
P
S
L
F
K
T
G
L
P
P
S
R
N
Site 32
S271
F
K
T
G
L
P
P
S
R
N
S
T
S
S
Q
Site 33
S274
G
L
P
P
S
R
N
S
T
S
S
Q
S
Q
T
Site 34
T275
L
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
Site 35
S276
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
Site 36
S277
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
A
Site 37
S279
R
N
S
T
S
S
Q
S
Q
T
S
T
A
S
R
Site 38
T281
S
T
S
S
Q
S
Q
T
S
T
A
S
R
K
A
Site 39
T283
S
S
Q
S
Q
T
S
T
A
S
R
K
A
N
S
Site 40
S285
Q
S
Q
T
S
T
A
S
R
K
A
N
S
S
V
Site 41
S291
A
S
R
K
A
N
S
S
V
G
K
W
Q
D
R
Site 42
Y299
V
G
K
W
Q
D
R
Y
G
R
A
E
S
P
D
Site 43
S304
D
R
Y
G
R
A
E
S
P
D
L
R
R
L
P
Site 44
T322
D
V
I
G
Q
T
I
T
I
S
R
V
E
G
R
Site 45
S324
I
G
Q
T
I
T
I
S
R
V
E
G
R
R
R
Site 46
S336
R
R
R
A
N
E
N
S
N
I
Q
V
L
S
E
Site 47
S342
N
S
N
I
Q
V
L
S
E
R
S
A
T
E
V
Site 48
T347
V
L
S
E
R
S
A
T
E
V
D
N
N
F
S
Site 49
S354
T
E
V
D
N
N
F
S
K
P
P
P
F
F
P
Site 50
T367
F
P
P
G
A
P
P
T
H
L
P
P
P
P
F
Site 51
T383
P
P
P
P
T
V
S
T
A
P
P
L
I
P
P
Site 52
S403
P
P
G
A
P
P
P
S
L
I
P
T
I
E
S
Site 53
T407
P
P
P
S
L
I
P
T
I
E
S
G
H
S
S
Site 54
S410
S
L
I
P
T
I
E
S
G
H
S
S
G
Y
D
Site 55
S414
T
I
E
S
G
H
S
S
G
Y
D
S
R
S
A
Site 56
Y416
E
S
G
H
S
S
G
Y
D
S
R
S
A
R
A
Site 57
S418
G
H
S
S
G
Y
D
S
R
S
A
R
A
F
P
Site 58
S420
S
S
G
Y
D
S
R
S
A
R
A
F
P
Y
G
Site 59
Y426
R
S
A
R
A
F
P
Y
G
N
V
A
F
P
H
Site 60
S437
A
F
P
H
L
P
G
S
A
P
S
W
P
S
L
Site 61
S440
H
L
P
G
S
A
P
S
W
P
S
L
V
D
T
Site 62
S443
G
S
A
P
S
W
P
S
L
V
D
T
S
K
Q
Site 63
Y453
D
T
S
K
Q
W
D
Y
Y
A
R
R
E
K
D
Site 64
Y454
T
S
K
Q
W
D
Y
Y
A
R
R
E
K
D
R
Site 65
T482
R
D
R
E
R
E
R
T
R
E
R
E
R
E
R
Site 66
S492
R
E
R
E
R
D
H
S
P
T
P
S
V
F
N
Site 67
T494
R
E
R
D
H
S
P
T
P
S
V
F
N
S
D
Site 68
S496
R
D
H
S
P
T
P
S
V
F
N
S
D
E
E
Site 69
S500
P
T
P
S
V
F
N
S
D
E
E
R
Y
R
Y
Site 70
Y505
F
N
S
D
E
E
R
Y
R
Y
R
E
Y
A
E
Site 71
Y507
S
D
E
E
R
Y
R
Y
R
E
Y
A
E
R
G
Site 72
Y510
E
R
Y
R
Y
R
E
Y
A
E
R
G
Y
E
R
Site 73
Y515
R
E
Y
A
E
R
G
Y
E
R
H
R
A
S
R
Site 74
S521
G
Y
E
R
H
R
A
S
R
E
K
E
E
R
H
Site 75
T539
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Site 76
S543
K
E
E
T
R
H
K
S
S
R
S
N
S
R
R
Site 77
S544
E
E
T
R
H
K
S
S
R
S
N
S
R
R
R
Site 78
S546
T
R
H
K
S
S
R
S
N
S
R
R
R
H
E
Site 79
S548
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Site 80
S554
N
S
R
R
R
H
E
S
E
E
G
D
S
H
R
Site 81
S559
H
E
S
E
E
G
D
S
H
R
R
H
K
H
K
Site 82
S568
R
R
H
K
H
K
K
S
K
R
S
K
E
G
K
Site 83
S579
K
E
G
K
E
A
G
S
E
P
A
P
E
Q
E
Site 84
S587
E
P
A
P
E
Q
E
S
T
E
A
T
P
A
E
Site 85
T588
P
A
P
E
Q
E
S
T
E
A
T
P
A
E
_
Site 86
T591
E
Q
E
S
T
E
A
T
P
A
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation