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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MECT1
Full Name:
CREB-regulated transcription coactivator 1
Alias:
CREB regulated transcription coactivator 1; CRTC1; FLJ14027; KIAA0616; Mucoepidermoid carcinoma translocated protein 1; TORC1; Transducer of CREB protein 1
Type:
Transcription protein
Mass (Da):
67300
Number AA:
634
UniProt ID:
Q6UUV9
International Prot ID:
IPI00783099
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008140
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
GO:0045944
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
N
N
P
R
K
F
S
E
K
I
A
L
H
N
Site 2
S36
E
E
V
M
K
D
L
S
L
T
R
A
A
R
L
Site 3
S48
A
R
L
Q
L
Q
K
S
Q
Y
L
Q
L
G
P
Site 4
Y50
L
Q
L
Q
K
S
Q
Y
L
Q
L
G
P
S
R
Site 5
S56
Q
Y
L
Q
L
G
P
S
R
G
Q
Y
Y
G
G
Site 6
Y60
L
G
P
S
R
G
Q
Y
Y
G
G
S
L
P
N
Site 7
Y61
G
P
S
R
G
Q
Y
Y
G
G
S
L
P
N
V
Site 8
S64
R
G
Q
Y
Y
G
G
S
L
P
N
V
N
Q
I
Site 9
T82
T
M
D
L
P
F
Q
T
P
F
Q
S
S
G
L
Site 10
S86
P
F
Q
T
P
F
Q
S
S
G
L
D
T
S
R
Site 11
T91
F
Q
S
S
G
L
D
T
S
R
T
T
R
H
H
Site 12
S92
Q
S
S
G
L
D
T
S
R
T
T
R
H
H
G
Site 13
T94
S
G
L
D
T
S
R
T
T
R
H
H
G
L
V
Site 14
T95
G
L
D
T
S
R
T
T
R
H
H
G
L
V
D
Site 15
Y105
H
G
L
V
D
R
V
Y
R
E
R
G
R
L
G
Site 16
S113
R
E
R
G
R
L
G
S
P
H
R
R
P
L
S
Site 17
S120
S
P
H
R
R
P
L
S
V
D
K
H
G
R
Q
Site 18
Y133
R
Q
A
D
S
C
P
Y
G
T
M
Y
L
S
P
Site 19
T135
A
D
S
C
P
Y
G
T
M
Y
L
S
P
P
A
Site 20
Y137
S
C
P
Y
G
T
M
Y
L
S
P
P
A
D
T
Site 21
S139
P
Y
G
T
M
Y
L
S
P
P
A
D
T
S
W
Site 22
S145
L
S
P
P
A
D
T
S
W
R
R
T
N
S
D
Site 23
T149
A
D
T
S
W
R
R
T
N
S
D
S
A
L
H
Site 24
S151
T
S
W
R
R
T
N
S
D
S
A
L
H
Q
S
Site 25
S153
W
R
R
T
N
S
D
S
A
L
H
Q
S
T
M
Site 26
S158
S
D
S
A
L
H
Q
S
T
M
T
P
T
Q
P
Site 27
T161
A
L
H
Q
S
T
M
T
P
T
Q
P
E
S
F
Site 28
T163
H
Q
S
T
M
T
P
T
Q
P
E
S
F
S
S
Site 29
S167
M
T
P
T
Q
P
E
S
F
S
S
G
S
Q
D
Site 30
S170
T
Q
P
E
S
F
S
S
G
S
Q
D
V
H
Q
Site 31
S172
P
E
S
F
S
S
G
S
Q
D
V
H
Q
K
R
Site 32
T184
Q
K
R
V
L
L
L
T
V
P
G
M
E
E
T
Site 33
S193
P
G
M
E
E
T
T
S
E
A
D
K
N
L
S
Site 34
T209
Q
A
W
D
T
K
K
T
G
S
R
P
K
S
C
Site 35
S211
W
D
T
K
K
T
G
S
R
P
K
S
C
E
V
Site 36
S215
K
T
G
S
R
P
K
S
C
E
V
P
G
I
N
Site 37
S226
P
G
I
N
I
F
P
S
A
D
Q
E
N
T
T
Site 38
T250
G
G
S
L
P
D
L
T
N
I
H
F
P
S
P
Site 39
S256
L
T
N
I
H
F
P
S
P
L
P
T
P
L
D
Site 40
T260
H
F
P
S
P
L
P
T
P
L
D
P
E
E
P
Site 41
T268
P
L
D
P
E
E
P
T
F
P
A
L
S
S
S
Site 42
S273
E
P
T
F
P
A
L
S
S
S
S
S
T
G
N
Site 43
S274
P
T
F
P
A
L
S
S
S
S
S
T
G
N
L
Site 44
S275
T
F
P
A
L
S
S
S
S
S
T
G
N
L
A
Site 45
S277
P
A
L
S
S
S
S
S
T
G
N
L
A
A
N
Site 46
S298
G
G
A
G
Q
G
M
S
T
P
G
S
S
P
Q
Site 47
T299
G
A
G
Q
G
M
S
T
P
G
S
S
P
Q
H
Site 48
S302
Q
G
M
S
T
P
G
S
S
P
Q
H
R
P
A
Site 49
S303
G
M
S
T
P
G
S
S
P
Q
H
R
P
A
G
Site 50
S312
Q
H
R
P
A
G
V
S
P
L
S
L
S
T
E
Site 51
S315
P
A
G
V
S
P
L
S
L
S
T
E
A
R
R
Site 52
S317
G
V
S
P
L
S
L
S
T
E
A
R
R
Q
Q
Site 53
S326
E
A
R
R
Q
Q
A
S
P
T
L
S
P
L
S
Site 54
T328
R
R
Q
Q
A
S
P
T
L
S
P
L
S
P
I
Site 55
S330
Q
Q
A
S
P
T
L
S
P
L
S
P
I
T
Q
Site 56
S333
S
P
T
L
S
P
L
S
P
I
T
Q
A
V
A
Site 57
T356
Q
L
P
Y
A
F
F
T
Q
A
G
S
Q
Q
P
Site 58
S360
A
F
F
T
Q
A
G
S
Q
Q
P
P
P
Q
P
Site 59
S377
P
P
P
P
P
P
A
S
Q
Q
P
P
P
P
P
Site 60
S401
P
G
G
P
L
L
P
S
A
S
L
T
R
G
P
Site 61
S403
G
P
L
L
P
S
A
S
L
T
R
G
P
Q
P
Site 62
T405
L
L
P
S
A
S
L
T
R
G
P
Q
P
P
P
Site 63
T416
Q
P
P
P
L
A
V
T
V
P
S
S
L
P
Q
Site 64
S420
L
A
V
T
V
P
S
S
L
P
Q
S
P
P
E
Site 65
S424
V
P
S
S
L
P
Q
S
P
P
E
N
P
G
Q
Site 66
Y447
S
A
P
A
L
Q
Q
Y
R
T
S
A
G
S
P
Site 67
T449
P
A
L
Q
Q
Y
R
T
S
A
G
S
P
A
N
Site 68
S450
A
L
Q
Q
Y
R
T
S
A
G
S
P
A
N
Q
Site 69
S453
Q
Y
R
T
S
A
G
S
P
A
N
Q
S
P
T
Site 70
S458
A
G
S
P
A
N
Q
S
P
T
S
P
V
S
N
Site 71
T460
S
P
A
N
Q
S
P
T
S
P
V
S
N
Q
G
Site 72
S461
P
A
N
Q
S
P
T
S
P
V
S
N
Q
G
F
Site 73
S464
Q
S
P
T
S
P
V
S
N
Q
G
F
S
P
G
Site 74
S469
P
V
S
N
Q
G
F
S
P
G
S
S
P
Q
H
Site 75
S472
N
Q
G
F
S
P
G
S
S
P
Q
H
T
S
T
Site 76
S473
Q
G
F
S
P
G
S
S
P
Q
H
T
S
T
L
Site 77
T477
P
G
S
S
P
Q
H
T
S
T
L
G
S
V
F
Site 78
S478
G
S
S
P
Q
H
T
S
T
L
G
S
V
F
G
Site 79
T479
S
S
P
Q
H
T
S
T
L
G
S
V
F
G
D
Site 80
S482
Q
H
T
S
T
L
G
S
V
F
G
D
A
Y
Y
Site 81
Y488
G
S
V
F
G
D
A
Y
Y
E
Q
Q
M
A
A
Site 82
Y489
S
V
F
G
D
A
Y
Y
E
Q
Q
M
A
A
R
Site 83
S516
N
M
M
E
N
A
I
S
S
S
S
L
Y
S
P
Site 84
S517
M
M
E
N
A
I
S
S
S
S
L
Y
S
P
G
Site 85
S518
M
E
N
A
I
S
S
S
S
L
Y
S
P
G
S
Site 86
S519
E
N
A
I
S
S
S
S
L
Y
S
P
G
S
T
Site 87
Y521
A
I
S
S
S
S
L
Y
S
P
G
S
T
L
N
Site 88
S522
I
S
S
S
S
L
Y
S
P
G
S
T
L
N
Y
Site 89
S525
S
S
L
Y
S
P
G
S
T
L
N
Y
S
Q
A
Site 90
T526
S
L
Y
S
P
G
S
T
L
N
Y
S
Q
A
A
Site 91
Y529
S
P
G
S
T
L
N
Y
S
Q
A
A
M
M
G
Site 92
S530
P
G
S
T
L
N
Y
S
Q
A
A
M
M
G
L
Site 93
S540
A
M
M
G
L
T
G
S
H
G
S
L
P
D
S
Site 94
S543
G
L
T
G
S
H
G
S
L
P
D
S
Q
Q
L
Site 95
S547
S
H
G
S
L
P
D
S
Q
Q
L
G
Y
A
S
Site 96
Y552
P
D
S
Q
Q
L
G
Y
A
S
H
S
G
I
P
Site 97
S554
S
Q
Q
L
G
Y
A
S
H
S
G
I
P
N
I
Site 98
S569
I
L
T
V
T
G
E
S
P
P
S
L
S
K
E
Site 99
S572
V
T
G
E
S
P
P
S
L
S
K
E
L
T
S
Site 100
S574
G
E
S
P
P
S
L
S
K
E
L
T
S
S
L
Site 101
T578
P
S
L
S
K
E
L
T
S
S
L
A
G
V
G
Site 102
S588
L
A
G
V
G
D
V
S
F
D
S
D
S
Q
F
Site 103
S591
V
G
D
V
S
F
D
S
D
S
Q
F
P
L
D
Site 104
S593
D
V
S
F
D
S
D
S
Q
F
P
L
D
E
L
Site 105
T625
M
V
L
A
D
P
A
T
E
D
T
F
R
M
D
Site 106
T628
A
D
P
A
T
E
D
T
F
R
M
D
R
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation