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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIRREL2
Full Name:
Kin of IRRE-like protein 2
Alias:
FILTRIN; Kin of irregular chiasm-like 2; Kin of IRRE-like 2; KIRR2; NEPH3; Nephrin-like 3; NLG1
Type:
Adhesion
Mass (Da):
75093
Number AA:
708
UniProt ID:
Q6UWL6
International Prot ID:
IPI00063735
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0007155
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T508
G
R
R
D
L
L
P
T
V
R
I
V
A
G
V
Site 2
S540
C
W
R
H
S
K
A
S
A
S
F
S
E
Q
K
Site 3
S542
R
H
S
K
A
S
A
S
F
S
E
Q
K
N
L
Site 4
S544
S
K
A
S
A
S
F
S
E
Q
K
N
L
M
R
Site 5
S555
N
L
M
R
I
P
G
S
S
D
G
S
S
S
R
Site 6
S556
L
M
R
I
P
G
S
S
D
G
S
S
S
R
G
Site 7
S559
I
P
G
S
S
D
G
S
S
S
R
G
P
E
E
Site 8
S560
P
G
S
S
D
G
S
S
S
R
G
P
E
E
E
Site 9
S561
G
S
S
D
G
S
S
S
R
G
P
E
E
E
E
Site 10
T569
R
G
P
E
E
E
E
T
G
S
R
E
D
R
G
Site 11
S571
P
E
E
E
E
T
G
S
R
E
D
R
G
P
I
Site 12
S584
P
I
V
H
T
D
H
S
D
L
V
L
E
E
E
Site 13
T593
L
V
L
E
E
E
G
T
L
E
T
K
D
P
T
Site 14
T596
E
E
E
G
T
L
E
T
K
D
P
T
N
G
Y
Site 15
Y603
T
K
D
P
T
N
G
Y
Y
K
V
R
G
V
S
Site 16
Y604
K
D
P
T
N
G
Y
Y
K
V
R
G
V
S
V
Site 17
S610
Y
Y
K
V
R
G
V
S
V
S
L
S
L
G
E
Site 18
T636
S
P
L
G
P
P
G
T
P
T
F
Y
D
F
N
Site 19
T638
L
G
P
P
G
T
P
T
F
Y
D
F
N
P
H
Site 20
Y640
P
P
G
T
P
T
F
Y
D
F
N
P
H
L
G
Site 21
Y655
M
V
P
P
C
R
L
Y
R
A
R
A
G
Y
L
Site 22
Y661
L
Y
R
A
R
A
G
Y
L
T
T
P
H
P
R
Site 23
T663
R
A
R
A
G
Y
L
T
T
P
H
P
R
A
F
Site 24
T664
A
R
A
G
Y
L
T
T
P
H
P
R
A
F
T
Site 25
T671
T
P
H
P
R
A
F
T
S
Y
I
K
P
T
S
Site 26
S672
P
H
P
R
A
F
T
S
Y
I
K
P
T
S
F
Site 27
Y673
H
P
R
A
F
T
S
Y
I
K
P
T
S
F
G
Site 28
S678
T
S
Y
I
K
P
T
S
F
G
P
P
D
L
A
Site 29
T688
P
P
D
L
A
P
G
T
P
P
F
P
Y
A
A
Site 30
Y693
P
G
T
P
P
F
P
Y
A
A
F
P
T
P
S
Site 31
T698
F
P
Y
A
A
F
P
T
P
S
H
P
R
L
Q
Site 32
S700
Y
A
A
F
P
T
P
S
H
P
R
L
Q
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation