KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HHIPL2
Full Name:
HHIP-like protein 2
Alias:
Type:
Mass (Da):
80779
Number AA:
724
UniProt ID:
Q6UWX4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y48
G
H
P
Q
C
L
D
Y
G
P
P
F
Q
P
P
Site 2
Y64
H
L
E
F
C
S
D
Y
E
S
F
G
C
C
D
Site 3
Y82
D
R
R
I
A
A
R
Y
W
D
I
M
E
Y
F
Site 4
Y88
R
Y
W
D
I
M
E
Y
F
D
L
K
R
H
E
Site 5
Y100
R
H
E
L
C
G
D
Y
I
K
D
I
L
C
Q
Site 6
Y112
L
C
Q
E
C
S
P
Y
A
A
H
L
Y
D
A
Site 7
Y117
S
P
Y
A
A
H
L
Y
D
A
E
N
T
Q
T
Site 8
T124
Y
D
A
E
N
T
Q
T
P
L
R
N
L
P
G
Site 9
Y136
L
P
G
L
C
S
D
Y
C
S
A
F
H
S
N
Site 10
S149
S
N
C
H
S
A
I
S
L
L
T
N
D
R
G
Site 11
S160
N
D
R
G
L
Q
E
S
H
G
R
D
G
T
R
Site 12
T166
E
S
H
G
R
D
G
T
R
F
C
H
L
L
D
Site 13
Y179
L
D
L
P
D
K
D
Y
C
F
P
N
V
L
R
Site 14
Y189
P
N
V
L
R
N
D
Y
L
N
R
H
L
G
M
Site 15
S221
N
G
L
R
N
P
V
S
M
V
H
A
G
D
G
Site 16
T229
M
V
H
A
G
D
G
T
H
R
F
F
V
A
E
Site 17
T265
L
K
N
I
V
L
T
T
P
W
I
G
D
E
R
Site 18
Y290
F
R
H
N
R
K
F
Y
I
Y
Y
S
C
L
D
Site 19
Y292
H
N
R
K
F
Y
I
Y
Y
S
C
L
D
K
K
Site 20
Y293
N
R
K
F
Y
I
Y
Y
S
C
L
D
K
K
K
Site 21
S307
K
V
E
K
I
R
I
S
E
M
K
V
S
R
A
Site 22
S312
R
I
S
E
M
K
V
S
R
A
D
P
N
K
A
Site 23
S323
P
N
K
A
D
L
K
S
E
R
V
I
L
E
I
Site 24
S335
L
E
I
E
E
P
A
S
N
H
N
G
G
Q
L
Site 25
T354
D
G
Y
M
Y
I
F
T
G
D
G
G
Q
A
G
Site 26
S374
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Site 27
S390
I
D
V
N
R
A
G
S
H
G
K
R
Y
R
V
Site 28
Y395
A
G
S
H
G
K
R
Y
R
V
P
S
D
N
P
Site 29
S399
G
K
R
Y
R
V
P
S
D
N
P
F
V
S
E
Site 30
S405
P
S
D
N
P
F
V
S
E
P
G
A
H
P
A
Site 31
Y414
P
G
A
H
P
A
I
Y
A
Y
G
I
R
N
M
Site 32
Y416
A
H
P
A
I
Y
A
Y
G
I
R
N
M
W
R
Site 33
T433
V
D
R
G
D
P
I
T
R
Q
G
R
G
R
I
Site 34
Y462
L
I
L
K
G
G
N
Y
G
W
R
A
K
E
G
Site 35
Y473
A
K
E
G
F
A
C
Y
D
K
K
L
C
H
N
Site 36
S482
K
K
L
C
H
N
A
S
L
D
D
V
L
P
I
Site 37
S499
Y
G
H
A
V
G
K
S
V
T
G
G
Y
V
Y
Site 38
Y504
G
K
S
V
T
G
G
Y
V
Y
R
G
C
E
S
Site 39
Y506
S
V
T
G
G
Y
V
Y
R
G
C
E
S
P
N
Site 40
S511
Y
V
Y
R
G
C
E
S
P
N
L
N
G
L
Y
Site 41
S549
K
Q
D
L
C
L
G
S
T
T
S
C
A
F
P
Site 42
S568
T
H
S
K
F
I
I
S
F
A
E
D
E
A
G
Site 43
Y578
E
D
E
A
G
E
L
Y
F
L
A
T
S
Y
P
Site 44
Y584
L
Y
F
L
A
T
S
Y
P
S
A
Y
A
P
R
Site 45
Y588
A
T
S
Y
P
S
A
Y
A
P
R
G
S
I
Y
Site 46
S593
S
A
Y
A
P
R
G
S
I
Y
K
F
V
D
P
Site 47
Y595
Y
A
P
R
G
S
I
Y
K
F
V
D
P
S
R
Site 48
S601
I
Y
K
F
V
D
P
S
R
R
A
P
P
G
K
Site 49
Y611
A
P
P
G
K
C
K
Y
K
P
V
P
V
R
T
Site 50
S620
P
V
P
V
R
T
K
S
K
R
I
P
F
R
P
Site 51
S640
L
D
L
L
K
E
Q
S
E
K
A
A
R
K
S
Site 52
S647
S
E
K
A
A
R
K
S
S
S
A
T
L
A
S
Site 53
S648
E
K
A
A
R
K
S
S
S
A
T
L
A
S
G
Site 54
S649
K
A
A
R
K
S
S
S
A
T
L
A
S
G
P
Site 55
T651
A
R
K
S
S
S
A
T
L
A
S
G
P
A
Q
Site 56
S654
S
S
S
A
T
L
A
S
G
P
A
Q
G
L
S
Site 57
S661
S
G
P
A
Q
G
L
S
E
K
G
S
S
K
K
Site 58
S665
Q
G
L
S
E
K
G
S
S
K
K
L
A
S
P
Site 59
S671
G
S
S
K
K
L
A
S
P
T
S
S
K
N
T
Site 60
S674
K
K
L
A
S
P
T
S
S
K
N
T
L
R
G
Site 61
S675
K
L
A
S
P
T
S
S
K
N
T
L
R
G
P
Site 62
T678
S
P
T
S
S
K
N
T
L
R
G
P
G
T
K
Site 63
S702
R
Q
G
K
R
R
K
S
L
K
S
H
S
G
R
Site 64
S705
K
R
R
K
S
L
K
S
H
S
G
R
M
R
P
Site 65
S707
R
K
S
L
K
S
H
S
G
R
M
R
P
S
A
Site 66
S713
H
S
G
R
M
R
P
S
A
E
Q
K
R
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation