KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ARSK
Full Name:
Arylsulfatase K
Alias:
arylsulfatase family, member K; arylsulfatase K; ASK; DKFZp313G1735; telethon sulfatase; TSULF
Type:
Hydrolase; EC 3.1.6.-
Mass (Da):
61450
Number AA:
UniProt ID:
Q6UWY0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004065
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T47
D
S
F
D
G
R
L
T
F
H
P
G
S
Q
V
Site 2
T65
P
F
I
N
F
M
K
T
R
G
T
S
F
L
N
Site 3
T68
N
F
M
K
T
R
G
T
S
F
L
N
A
Y
T
Site 4
S69
F
M
K
T
R
G
T
S
F
L
N
A
Y
T
N
Site 5
Y74
G
T
S
F
L
N
A
Y
T
N
S
P
I
C
C
Site 6
S77
F
L
N
A
Y
T
N
S
P
I
C
C
P
S
R
Site 7
T96
S
G
L
F
T
H
L
T
E
S
W
N
N
F
K
Site 8
Y109
F
K
G
L
D
P
N
Y
T
T
W
M
D
V
M
Site 9
Y121
D
V
M
E
R
H
G
Y
R
T
Q
K
F
G
K
Site 10
T123
M
E
R
H
G
Y
R
T
Q
K
F
G
K
L
D
Site 11
Y131
Q
K
F
G
K
L
D
Y
T
S
G
H
H
S
I
Site 12
T132
K
F
G
K
L
D
Y
T
S
G
H
H
S
I
S
Site 13
S133
F
G
K
L
D
Y
T
S
G
H
H
S
I
S
N
Site 14
S137
D
Y
T
S
G
H
H
S
I
S
N
R
V
E
A
Site 15
S139
T
S
G
H
H
S
I
S
N
R
V
E
A
W
T
Site 16
T146
S
N
R
V
E
A
W
T
R
D
V
A
F
L
L
Site 17
T168
V
N
L
I
R
N
R
T
K
V
R
V
M
E
R
Site 18
Y194
L
R
K
E
A
I
N
Y
T
E
P
F
V
I
Y
Site 19
Y210
G
L
N
L
P
H
P
Y
P
S
P
S
S
G
E
Site 20
S212
N
L
P
H
P
Y
P
S
P
S
S
G
E
N
F
Site 21
S214
P
H
P
Y
P
S
P
S
S
G
E
N
F
G
S
Site 22
S215
H
P
Y
P
S
P
S
S
G
E
N
F
G
S
S
Site 23
S221
S
S
G
E
N
F
G
S
S
T
F
H
T
S
L
Site 24
S222
S
G
E
N
F
G
S
S
T
F
H
T
S
L
Y
Site 25
T223
G
E
N
F
G
S
S
T
F
H
T
S
L
Y
W
Site 26
T226
F
G
S
S
T
F
H
T
S
L
Y
W
L
E
K
Site 27
S227
G
S
S
T
F
H
T
S
L
Y
W
L
E
K
V
Site 28
Y229
S
T
F
H
T
S
L
Y
W
L
E
K
V
S
H
Site 29
S245
A
I
K
I
P
K
W
S
P
L
S
E
M
H
P
Site 30
S248
I
P
K
W
S
P
L
S
E
M
H
P
V
D
Y
Site 31
Y255
S
E
M
H
P
V
D
Y
Y
S
S
Y
T
K
N
Site 32
Y256
E
M
H
P
V
D
Y
Y
S
S
Y
T
K
N
C
Site 33
Y259
P
V
D
Y
Y
S
S
Y
T
K
N
C
T
G
R
Site 34
T268
K
N
C
T
G
R
F
T
K
K
E
I
K
N
I
Site 35
Y280
K
N
I
R
A
F
Y
Y
A
M
C
A
E
T
D
Site 36
Y310
L
Q
K
T
I
V
I
Y
S
S
D
H
G
E
L
Site 37
Y325
A
M
E
H
R
Q
F
Y
K
M
S
M
Y
E
A
Site 38
Y330
Q
F
Y
K
M
S
M
Y
E
A
S
A
H
V
P
Site 39
S380
P
Q
N
L
S
G
Y
S
L
L
P
L
S
S
E
Site 40
S385
G
Y
S
L
L
P
L
S
S
E
T
F
K
N
E
Site 41
S386
Y
S
L
L
P
L
S
S
E
T
F
K
N
E
H
Site 42
Y426
L
R
T
N
H
W
K
Y
I
A
Y
S
D
G
A
Site 43
S443
L
P
Q
L
F
D
L
S
S
D
P
D
E
L
T
Site 44
S444
P
Q
L
F
D
L
S
S
D
P
D
E
L
T
N
Site 45
T450
S
S
D
P
D
E
L
T
N
V
A
V
K
F
P
Site 46
S462
K
F
P
E
I
T
Y
S
L
D
Q
K
L
H
S
Site 47
S469
S
L
D
Q
K
L
H
S
I
I
N
Y
P
K
V
Site 48
Y483
V
S
A
S
V
H
Q
Y
N
K
E
Q
F
I
K
Site 49
S500
Q
S
I
G
Q
N
Y
S
N
V
I
A
N
L
R
Site 50
Y519
W
Q
K
E
P
R
K
Y
E
N
A
I
D
Q
W
Site 51
T529
A
I
D
Q
W
L
K
T
H
M
N
P
R
A
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation