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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM175A
Full Name:
BRCA1-A complex subunit Abraxas
Alias:
ABRA1; Abraxas protein; CCD98; CCDC98; Coiled-coil domain containing 98; Family with sequence similarity 175, member A; FLJ11520; FLJ12642; FLJ13614; Protein FAM175A
Type:
DNA repair; Unknown function
Mass (Da):
46663
Number AA:
409
UniProt ID:
Q6UWZ7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070531
Uniprot
OncoNet
Molecular Function:
GO:0031593
PhosphoSite+
KinaseNET
Biological Process:
GO:0031572
GO:0016568
GO:0006302
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
G
E
S
T
S
A
V
L
S
G
Site 2
S27
F
Q
H
L
N
T
D
S
D
T
E
G
F
L
L
Site 3
T29
H
L
N
T
D
S
D
T
E
G
F
L
L
G
E
Site 4
S44
V
K
G
E
A
K
N
S
I
T
D
S
Q
M
D
Site 5
S48
A
K
N
S
I
T
D
S
Q
M
D
D
V
E
V
Site 6
Y57
M
D
D
V
E
V
V
Y
T
I
D
I
Q
K
Y
Site 7
Y68
I
Q
K
Y
I
P
C
Y
Q
L
F
S
F
Y
N
Site 8
Y74
C
Y
Q
L
F
S
F
Y
N
S
S
G
E
V
N
Site 9
S76
Q
L
F
S
F
Y
N
S
S
G
E
V
N
E
Q
Site 10
S90
Q
A
L
K
K
I
L
S
N
V
K
K
N
V
V
Site 11
Y100
K
K
N
V
V
G
W
Y
K
F
R
R
H
S
D
Site 12
T111
R
H
S
D
Q
I
M
T
F
R
E
R
L
L
H
Site 13
S126
K
N
L
Q
E
H
F
S
N
Q
D
L
V
F
L
Site 14
T141
L
L
T
P
S
I
I
T
E
S
C
S
T
H
R
Site 15
S145
S
I
I
T
E
S
C
S
T
H
R
L
E
H
S
Site 16
T146
I
I
T
E
S
C
S
T
H
R
L
E
H
S
L
Site 17
S152
S
T
H
R
L
E
H
S
L
Y
K
P
Q
K
G
Site 18
Y154
H
R
L
E
H
S
L
Y
K
P
Q
K
G
L
F
Site 19
Y179
G
M
S
E
Q
L
G
Y
K
T
V
S
G
S
C
Site 20
T181
S
E
Q
L
G
Y
K
T
V
S
G
S
C
M
S
Site 21
S183
Q
L
G
Y
K
T
V
S
G
S
C
M
S
T
G
Site 22
S185
G
Y
K
T
V
S
G
S
C
M
S
T
G
F
S
Site 23
S192
S
C
M
S
T
G
F
S
R
A
V
Q
T
H
S
Site 24
S200
R
A
V
Q
T
H
S
S
K
F
F
E
E
D
G
Site 25
S208
K
F
F
E
E
D
G
S
L
K
E
V
H
K
I
Site 26
S221
K
I
N
E
M
Y
A
S
L
Q
E
E
L
K
S
Site 27
S228
S
L
Q
E
E
L
K
S
I
C
K
K
V
E
D
Site 28
S236
I
C
K
K
V
E
D
S
E
Q
A
V
D
K
L
Site 29
S296
P
N
S
E
F
L
H
S
C
V
M
S
L
K
N
Site 30
S300
F
L
H
S
C
V
M
S
L
K
N
R
H
V
S
Site 31
S307
S
L
K
N
R
H
V
S
K
S
S
C
N
Y
N
Site 32
Y313
V
S
K
S
S
C
N
Y
N
H
H
L
D
V
V
Site 33
T330
L
T
L
M
V
E
H
T
D
I
P
E
A
S
P
Site 34
S336
H
T
D
I
P
E
A
S
P
A
S
T
P
Q
I
Site 35
S339
I
P
E
A
S
P
A
S
T
P
Q
I
I
K
H
Site 36
T340
P
E
A
S
P
A
S
T
P
Q
I
I
K
H
K
Site 37
T365
K
R
S
R
L
L
D
T
Q
D
K
R
S
K
A
Site 38
S370
L
D
T
Q
D
K
R
S
K
A
D
T
G
S
S
Site 39
T374
D
K
R
S
K
A
D
T
G
S
S
N
Q
D
K
Site 40
S376
R
S
K
A
D
T
G
S
S
N
Q
D
K
A
S
Site 41
S377
S
K
A
D
T
G
S
S
N
Q
D
K
A
S
K
Site 42
S383
S
S
N
Q
D
K
A
S
K
M
S
S
P
E
T
Site 43
S386
Q
D
K
A
S
K
M
S
S
P
E
T
D
E
E
Site 44
S387
D
K
A
S
K
M
S
S
P
E
T
D
E
E
I
Site 45
T390
S
K
M
S
S
P
E
T
D
E
E
I
E
K
M
Site 46
Y403
K
M
K
G
F
G
E
Y
S
R
S
P
T
F
_
Site 47
S404
M
K
G
F
G
E
Y
S
R
S
P
T
F
_
_
Site 48
S406
G
F
G
E
Y
S
R
S
P
T
F
_
_
_
_
Site 49
T408
G
E
Y
S
R
S
P
T
F
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation