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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC5D
Full Name:
Netrin receptor UNC5D
Alias:
Protein unc-5 homolog 4;Protein unc-5 homolog D
Type:
Mass (Da):
105880
Number AA:
953
UniProt ID:
Q6UXZ4
International Prot ID:
IPI00470696
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007275
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T210
E
Q
D
E
N
I
D
T
R
A
D
H
N
L
I
Site 2
Y403
L
V
I
G
V
T
L
Y
R
R
S
Q
S
D
Y
Site 3
S406
G
V
T
L
Y
R
R
S
Q
S
D
Y
G
V
D
Site 4
S408
T
L
Y
R
R
S
Q
S
D
Y
G
V
D
V
I
Site 5
Y410
Y
R
R
S
Q
S
D
Y
G
V
D
V
I
D
S
Site 6
T426
A
L
T
G
G
F
Q
T
F
N
F
K
T
V
R
Site 7
T431
F
Q
T
F
N
F
K
T
V
R
Q
G
N
S
L
Site 8
S437
K
T
V
R
Q
G
N
S
L
L
L
N
S
A
M
Site 9
T449
S
A
M
Q
P
D
L
T
V
S
R
T
Y
S
G
Site 10
S451
M
Q
P
D
L
T
V
S
R
T
Y
S
G
P
I
Site 11
Y454
D
L
T
V
S
R
T
Y
S
G
P
I
C
L
Q
Site 12
S455
L
T
V
S
R
T
Y
S
G
P
I
C
L
Q
D
Site 13
T470
P
L
D
K
E
L
M
T
E
S
S
L
F
N
P
Site 14
S473
K
E
L
M
T
E
S
S
L
F
N
P
L
S
D
Site 15
S479
S
S
L
F
N
P
L
S
D
I
K
V
K
V
Q
Site 16
S496
F
M
V
S
L
G
V
S
E
R
A
E
Y
H
G
Site 17
Y501
G
V
S
E
R
A
E
Y
H
G
K
N
H
S
R
Site 18
Y529
H
P
R
N
K
M
P
Y
I
Q
N
L
S
S
L
Site 19
S534
M
P
Y
I
Q
N
L
S
S
L
P
T
R
T
E
Site 20
S535
P
Y
I
Q
N
L
S
S
L
P
T
R
T
E
L
Site 21
T544
P
T
R
T
E
L
R
T
T
G
V
F
G
H
L
Site 22
T545
T
R
T
E
L
R
T
T
G
V
F
G
H
L
G
Site 23
Y580
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Site 24
S589
S
I
N
Q
G
E
P
S
L
Q
S
D
G
S
E
Site 25
S592
Q
G
E
P
S
L
Q
S
D
G
S
E
V
L
L
Site 26
S595
P
S
L
Q
S
D
G
S
E
V
L
L
S
P
E
Site 27
S600
D
G
S
E
V
L
L
S
P
E
V
T
C
G
P
Site 28
S649
G
K
W
E
E
V
M
S
V
E
D
E
S
T
S
Site 29
T655
M
S
V
E
D
E
S
T
S
C
Y
C
L
L
D
Site 30
S656
S
V
E
D
E
S
T
S
C
Y
C
L
L
D
P
Site 31
Y658
E
D
E
S
T
S
C
Y
C
L
L
D
P
F
A
Site 32
Y711
L
D
Y
N
L
R
V
Y
C
V
D
N
T
P
C
Site 33
S725
C
A
F
Q
E
V
V
S
D
E
R
H
Q
G
G
Site 34
S749
H
F
K
G
N
T
F
S
L
Q
I
S
V
L
D
Site 35
S791
Q
P
L
H
C
A
F
S
L
E
R
Y
T
P
T
Site 36
Y795
C
A
F
S
L
E
R
Y
T
P
T
T
T
Q
L
Site 37
T796
A
F
S
L
E
R
Y
T
P
T
T
T
Q
L
S
Site 38
T798
S
L
E
R
Y
T
P
T
T
T
Q
L
S
C
K
Site 39
T799
L
E
R
Y
T
P
T
T
T
Q
L
S
C
K
I
Site 40
S823
Q
I
L
Q
V
Q
T
S
I
L
E
S
E
R
E
Site 41
S827
V
Q
T
S
I
L
E
S
E
R
E
T
I
T
F
Site 42
T831
I
L
E
S
E
R
E
T
I
T
F
F
A
Q
E
Site 43
T833
E
S
E
R
E
T
I
T
F
F
A
Q
E
D
S
Site 44
T841
F
F
A
Q
E
D
S
T
F
P
A
Q
T
G
P
Site 45
T864
I
R
Q
R
I
C
A
T
F
D
T
P
N
A
K
Site 46
T867
R
I
C
A
T
F
D
T
P
N
A
K
G
K
D
Site 47
S883
Q
M
L
A
Q
K
N
S
I
N
R
N
L
S
Y
Site 48
S889
N
S
I
N
R
N
L
S
Y
F
A
T
Q
S
S
Site 49
Y890
S
I
N
R
N
L
S
Y
F
A
T
Q
S
S
P
Site 50
T893
R
N
L
S
Y
F
A
T
Q
S
S
P
S
A
V
Site 51
S917
Q
H
D
G
D
L
D
S
L
A
C
A
L
E
E
Site 52
T928
A
L
E
E
I
G
R
T
H
T
K
L
S
N
I
Site 53
T930
E
E
I
G
R
T
H
T
K
L
S
N
I
S
E
Site 54
S933
G
R
T
H
T
K
L
S
N
I
S
E
S
Q
L
Site 55
S938
K
L
S
N
I
S
E
S
Q
L
D
E
A
D
F
Site 56
Y947
L
D
E
A
D
F
N
Y
S
R
Q
N
G
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation