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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCHS2
Full Name:
Protocadherin-23
Alias:
cadherin-like 27; cadherin-like protein VR8; CDH27; CDHJ; dachsous 2; FLJ20047; PCDH23; PCDHJ
Type:
Mass (Da):
322230
Number AA:
UniProt ID:
Q6V1P9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
R
L
D
E
I
T
K
S
E
N
E
D
G
Site 2
S9
R
L
D
E
I
T
K
S
E
N
E
D
G
E
K
Site 3
T20
D
G
E
K
K
M
F
T
Q
Q
F
E
S
T
D
Site 4
Y31
E
S
T
D
A
C
V
Y
E
V
Y
V
K
I
N
Site 5
S39
E
V
Y
V
K
I
N
S
I
V
K
S
Q
S
Q
Site 6
S43
K
I
N
S
I
V
K
S
Q
S
Q
C
G
L
K
Site 7
S45
N
S
I
V
K
S
Q
S
Q
C
G
L
K
R
G
Site 8
S53
Q
C
G
L
K
R
G
S
P
E
T
E
L
W
G
Site 9
T56
L
K
R
G
S
P
E
T
E
L
W
G
A
I
V
Site 10
S66
W
G
A
I
V
F
R
S
Q
E
E
N
A
K
P
Site 11
T80
P
V
K
E
T
E
V
T
A
S
D
A
D
S
G
Site 12
S82
K
E
T
E
V
T
A
S
D
A
D
S
G
L
Y
Site 13
Y89
S
D
A
D
S
G
L
Y
G
F
I
E
Y
S
L
Site 14
Y97
G
F
I
E
Y
S
L
Y
D
G
F
L
S
Y
E
Site 15
S102
S
L
Y
D
G
F
L
S
Y
E
A
P
Q
A
F
Site 16
Y103
L
Y
D
G
F
L
S
Y
E
A
P
Q
A
F
R
Site 17
S121
H
D
G
Q
I
C
V
S
Q
D
I
D
R
E
R
Site 18
T132
D
R
E
R
D
P
A
T
Y
D
L
L
V
E
A
Site 19
Y133
R
E
R
D
P
A
T
Y
D
L
L
V
E
A
K
Site 20
T148
D
G
D
E
Q
R
M
T
H
L
A
L
V
K
G
Site 21
S180
N
H
P
V
F
N
P
S
T
Y
V
T
S
I
S
Site 22
T181
H
P
V
F
N
P
S
T
Y
V
T
S
I
S
D
Site 23
Y182
P
V
F
N
P
S
T
Y
V
T
S
I
S
D
E
Site 24
T184
F
N
P
S
T
Y
V
T
S
I
S
D
E
T
Q
Site 25
S187
S
T
Y
V
T
S
I
S
D
E
T
Q
P
G
T
Site 26
T190
V
T
S
I
S
D
E
T
Q
P
G
T
E
I
I
Site 27
S229
S
S
L
F
T
I
D
S
T
T
G
L
Y
S
P
Site 28
S235
D
S
T
T
G
L
Y
S
P
E
V
E
I
L
S
Site 29
Y298
K
G
R
R
H
L
H
Y
L
K
V
Q
D
E
A
Site 30
S344
H
L
E
S
T
T
L
S
L
M
V
S
A
Q
D
Site 31
Y382
A
E
F
E
R
P
K
Y
T
F
L
V
Y
E
D
Site 32
Y387
P
K
Y
T
F
L
V
Y
E
D
V
P
E
D
S
Site 33
S394
Y
E
D
V
P
E
D
S
P
I
G
T
V
K
A
Site 34
T398
P
E
D
S
P
I
G
T
V
K
A
R
E
P
L
Site 35
S407
K
A
R
E
P
L
N
S
S
E
P
I
F
Y
R
Site 36
S408
A
R
E
P
L
N
S
S
E
P
I
F
Y
R
I
Site 37
Y413
N
S
S
E
P
I
F
Y
R
I
S
S
G
D
L
Site 38
S416
E
P
I
F
Y
R
I
S
S
G
D
L
G
G
K
Site 39
S417
P
I
F
Y
R
I
S
S
G
D
L
G
G
K
F
Site 40
S425
G
D
L
G
G
K
F
S
I
H
P
R
L
G
T
Site 41
T432
S
I
H
P
R
L
G
T
I
R
T
R
K
P
L
Site 42
T435
P
R
L
G
T
I
R
T
R
K
P
L
D
H
E
Site 43
T443
R
K
P
L
D
H
E
T
Q
P
V
V
V
L
T
Site 44
T469
S
S
T
E
V
N
I
T
V
M
D
V
N
D
N
Site 45
S484
H
P
A
F
L
R
T
S
D
E
I
R
I
S
Q
Site 46
S490
T
S
D
E
I
R
I
S
Q
T
T
P
P
G
T
Site 47
T492
D
E
I
R
I
S
Q
T
T
P
P
G
T
A
L
Site 48
T493
E
I
R
I
S
Q
T
T
P
P
G
T
A
L
Y
Site 49
Y500
T
P
P
G
T
A
L
Y
L
A
R
A
E
D
R
Site 50
S509
A
R
A
E
D
R
D
S
G
R
N
G
L
I
R
Site 51
Y517
G
R
N
G
L
I
R
Y
S
I
A
S
P
Q
P
Site 52
S518
R
N
G
L
I
R
Y
S
I
A
S
P
Q
P
G
Site 53
T551
A
G
E
Q
R
E
L
T
L
T
L
R
A
E
D
Site 54
T553
E
Q
R
E
L
T
L
T
L
R
A
E
D
Q
G
Site 55
S580
V
I
E
K
R
E
H
S
P
S
W
T
F
E
H
Site 56
S582
E
K
R
E
H
S
P
S
W
T
F
E
H
L
V
Site 57
T584
R
E
H
S
P
S
W
T
F
E
H
L
V
Y
Q
Site 58
Y590
W
T
F
E
H
L
V
Y
Q
V
E
V
S
E
S
Site 59
S597
Y
Q
V
E
V
S
E
S
L
S
P
M
T
Q
M
Site 60
S599
V
E
V
S
E
S
L
S
P
M
T
Q
M
L
Q
Site 61
S619
L
G
P
Q
R
A
A
S
P
L
R
Y
S
L
E
Site 62
S624
A
A
S
P
L
R
Y
S
L
E
P
S
V
D
S
Site 63
S628
L
R
Y
S
L
E
P
S
V
D
S
A
M
F
G
Site 64
S631
S
L
E
P
S
V
D
S
A
M
F
G
I
R
P
Site 65
Y644
R
P
Y
T
G
W
I
Y
L
R
R
Q
F
D
Y
Site 66
Y651
Y
L
R
R
Q
F
D
Y
E
S
T
Q
T
Y
N
Site 67
Y657
D
Y
E
S
T
Q
T
Y
N
F
R
V
F
A
W
Site 68
S689
V
W
D
E
N
D
N
S
P
T
F
L
H
D
V
Site 69
S721
I
T
A
I
D
M
D
S
G
K
N
G
Q
L
L
Site 70
Y729
G
K
N
G
Q
L
L
Y
F
L
L
S
D
G
K
Site 71
T744
F
F
K
M
N
P
N
T
G
P
A
G
T
I
Y
Site 72
T808
H
R
G
H
H
E
M
T
V
L
V
T
D
R
G
Site 73
T812
H
E
M
T
V
L
V
T
D
R
G
S
P
P
R
Site 74
S816
V
L
V
T
D
R
G
S
P
P
R
N
A
T
M
Site 75
T879
E
G
N
N
A
E
V
T
Y
S
V
S
S
E
D
Site 76
S881
N
N
A
E
V
T
Y
S
V
S
S
E
D
S
S
Site 77
S883
A
E
V
T
Y
S
V
S
S
E
D
S
S
D
H
Site 78
S884
E
V
T
Y
S
V
S
S
E
D
S
S
D
H
F
Site 79
S887
Y
S
V
S
S
E
D
S
S
D
H
F
K
I
D
Site 80
S888
S
V
S
S
E
D
S
S
D
H
F
K
I
D
A
Site 81
T903
N
N
G
E
I
R
T
T
T
I
L
S
Y
D
Y
Site 82
T904
N
G
E
I
R
T
T
T
I
L
S
Y
D
Y
R
Site 83
S907
I
R
T
T
T
I
L
S
Y
D
Y
R
P
S
Y
Site 84
Y910
T
T
I
L
S
Y
D
Y
R
P
S
Y
R
M
S
Site 85
S913
L
S
Y
D
Y
R
P
S
Y
R
M
S
V
I
A
Site 86
Y914
S
Y
D
Y
R
P
S
Y
R
M
S
V
I
A
T
Site 87
S917
Y
R
P
S
Y
R
M
S
V
I
A
T
D
Q
G
Site 88
S949
S
K
G
R
A
I
M
S
Q
N
I
R
H
L
I
Site 89
S968
L
K
P
T
K
I
M
S
L
I
K
S
S
D
H
Site 90
S972
K
I
M
S
L
I
K
S
S
D
H
L
Q
Q
H
Site 91
S1001
D
G
H
F
E
I
D
S
S
T
G
D
L
F
L
Site 92
S1002
G
H
F
E
I
D
S
S
T
G
D
L
F
L
S
Site 93
T1003
H
F
E
I
D
S
S
T
G
D
L
F
L
S
K
Site 94
S1009
S
T
G
D
L
F
L
S
K
E
L
D
Y
E
T
Site 95
Y1014
F
L
S
K
E
L
D
Y
E
T
T
S
H
Y
L
Site 96
T1016
S
K
E
L
D
Y
E
T
T
S
H
Y
L
F
R
Site 97
Y1020
D
Y
E
T
T
S
H
Y
L
F
R
V
I
T
T
Site 98
T1026
H
Y
L
F
R
V
I
T
T
D
H
S
K
N
L
Site 99
S1030
R
V
I
T
T
D
H
S
K
N
L
S
L
S
S
Site 100
S1034
T
D
H
S
K
N
L
S
L
S
S
T
V
F
L
Site 101
S1042
L
S
S
T
V
F
L
S
I
D
V
E
D
Q
N
Site 102
S1052
V
E
D
Q
N
D
H
S
P
S
F
Q
D
E
L
Site 103
S1054
D
Q
N
D
H
S
P
S
F
Q
D
E
L
I
V
Site 104
S1085
N
A
K
D
D
D
G
S
F
L
N
S
R
I
Q
Site 105
S1089
D
D
G
S
F
L
N
S
R
I
Q
Y
Y
I
E
Site 106
Y1093
F
L
N
S
R
I
Q
Y
Y
I
E
S
H
N
P
Site 107
Y1094
L
N
S
R
I
Q
Y
Y
I
E
S
H
N
P
G
Site 108
T1102
I
E
S
H
N
P
G
T
N
P
F
L
I
H
P
Site 109
T1116
P
S
F
G
T
L
V
T
V
S
R
L
D
R
E
Site 110
T1142
S
D
Q
A
V
N
V
T
D
R
R
L
R
S
L
Site 111
T1150
D
R
R
L
R
S
L
T
A
Q
I
V
I
L
D
Site 112
T1164
D
V
N
D
H
N
P
T
F
I
S
F
P
N
A
Site 113
T1178
A
H
V
K
E
D
V
T
V
G
S
L
V
H
H
Site 114
T1200
E
G
R
N
G
K
V
T
Y
S
I
L
S
G
N
Site 115
Y1201
G
R
N
G
K
V
T
Y
S
I
L
S
G
N
E
Site 116
S1202
R
N
G
K
V
T
Y
S
I
L
S
G
N
E
N
Site 117
T1211
L
S
G
N
E
N
M
T
F
M
L
D
E
S
S
Site 118
T1222
D
E
S
S
G
L
L
T
T
T
C
P
L
D
Y
Site 119
T1223
E
S
S
G
L
L
T
T
T
C
P
L
D
Y
E
Site 120
Y1229
T
T
T
C
P
L
D
Y
E
M
K
T
Q
H
I
Site 121
T1233
P
L
D
Y
E
M
K
T
Q
H
I
L
T
V
L
Site 122
S1250
D
D
G
T
P
A
L
S
S
S
Q
T
L
T
V
Site 123
T1258
S
S
Q
T
L
T
V
T
V
L
D
V
N
D
E
Site 124
Y1274
P
V
F
K
Q
H
L
Y
E
A
S
V
K
E
N
Site 125
S1298
V
E
A
L
D
R
D
S
G
V
N
S
K
L
Q
Site 126
S1302
D
R
D
S
G
V
N
S
K
L
Q
F
E
I
M
Site 127
T1341
R
E
I
Q
E
V
F
T
L
R
V
L
V
R
D
Site 128
S1353
V
R
D
G
G
F
P
S
L
S
S
T
T
T
I
Site 129
T1363
S
T
T
T
I
L
C
T
V
E
D
E
N
D
H
Site 130
T1394
Q
E
P
E
V
V
Y
T
V
L
A
S
D
M
D
Site 131
Y1410
G
N
N
R
A
V
E
Y
H
I
I
D
G
N
T
Site 132
S1431
N
E
M
S
G
E
L
S
T
T
R
A
L
D
R
Site 133
T1433
M
S
G
E
L
S
T
T
R
A
L
D
R
E
Q
Site 134
S1459
D
L
G
D
P
P
R
S
S
V
I
H
L
Q
V
Site 135
S1460
L
G
D
P
P
R
S
S
V
I
H
L
Q
V
R
Site 136
S1475
V
L
D
A
N
D
H
S
P
S
F
P
T
L
Y
Site 137
S1477
D
A
N
D
H
S
P
S
F
P
T
L
Y
Y
Q
Site 138
T1480
D
H
S
P
S
F
P
T
L
Y
Y
Q
S
S
V
Site 139
Y1482
S
P
S
F
P
T
L
Y
Y
Q
S
S
V
R
E
Site 140
Y1483
P
S
F
P
T
L
Y
Y
Q
S
S
V
R
E
D
Site 141
S1486
P
T
L
Y
Y
Q
S
S
V
R
E
D
A
E
V
Site 142
Y1515
G
L
N
G
Q
T
E
Y
F
L
T
D
E
A
S
Site 143
T1518
G
Q
T
E
Y
F
L
T
D
E
A
S
G
A
F
Site 144
T1526
D
E
A
S
G
A
F
T
I
D
P
M
S
G
T
Site 145
S1531
A
F
T
I
D
P
M
S
G
T
L
K
T
S
N
Site 146
T1533
T
I
D
P
M
S
G
T
L
K
T
S
N
T
L
Site 147
S1537
M
S
G
T
L
K
T
S
N
T
L
D
R
E
A
Site 148
T1539
G
T
L
K
T
S
N
T
L
D
R
E
A
R
S
Site 149
S1546
T
L
D
R
E
A
R
S
Q
H
T
F
S
A
V
Site 150
T1549
R
E
A
R
S
Q
H
T
F
S
A
V
A
R
D
Site 151
S1551
A
R
S
Q
H
T
F
S
A
V
A
R
D
C
S
Site 152
S1558
S
A
V
A
R
D
C
S
I
Q
G
S
R
S
T
Site 153
S1562
R
D
C
S
I
Q
G
S
R
S
T
T
V
I
I
Site 154
S1593
N
P
F
D
V
F
L
S
P
E
S
P
T
N
Q
Site 155
S1596
D
V
F
L
S
P
E
S
P
T
N
Q
T
T
V
Site 156
T1602
E
S
P
T
N
Q
T
T
V
I
V
R
A
D
D
Site 157
S1627
F
S
F
A
E
T
Q
S
M
F
S
I
D
K
Y
Site 158
Y1634
S
M
F
S
I
D
K
Y
T
G
E
I
Q
F
Q
Site 159
Y1648
Q
Q
N
P
S
S
E
Y
F
P
I
W
L
Q
L
Site 160
T1658
I
W
L
Q
L
K
V
T
D
Q
G
I
P
A
R
Site 161
S1683
E
G
E
D
V
K
I
S
F
S
H
H
L
Y
K
Site 162
Y1689
I
S
F
S
H
H
L
Y
K
G
L
V
T
E
N
Site 163
S1713
V
K
A
F
A
P
D
S
I
Q
D
S
M
K
Y
Site 164
S1717
A
P
D
S
I
Q
D
S
M
K
Y
S
I
F
S
Site 165
Y1720
S
I
Q
D
S
M
K
Y
S
I
F
S
G
N
E
Site 166
S1721
I
Q
D
S
M
K
Y
S
I
F
S
G
N
E
D
Site 167
S1732
G
N
E
D
G
V
L
S
L
C
S
K
S
G
Q
Site 168
T1741
C
S
K
S
G
Q
L
T
V
K
E
P
K
F
L
Site 169
S1784
I
Q
D
E
N
D
N
S
P
C
F
E
Q
S
I
Site 170
S1790
N
S
P
C
F
E
Q
S
I
Y
Q
A
S
V
S
Site 171
Y1792
P
C
F
E
Q
S
I
Y
Q
A
S
V
S
E
S
Site 172
S1795
E
Q
S
I
Y
Q
A
S
V
S
E
S
Q
L
Y
Site 173
S1797
S
I
Y
Q
A
S
V
S
E
S
Q
L
Y
N
A
Site 174
S1799
Y
Q
A
S
V
S
E
S
Q
L
Y
N
A
H
V
Site 175
Y1802
S
V
S
E
S
Q
L
Y
N
A
H
V
I
Q
V
Site 176
Y1852
T
T
K
A
I
L
D
Y
E
L
T
S
S
Y
S
Site 177
S1859
Y
E
L
T
S
S
Y
S
L
I
V
Q
A
T
D
Site 178
T1865
Y
S
L
I
V
Q
A
T
D
K
G
M
P
R
L
Site 179
S1873
D
K
G
M
P
R
L
S
N
T
T
V
I
K
V
Site 180
S1927
L
N
S
A
F
I
F
S
F
A
K
E
S
N
P
Site 181
T1936
A
K
E
S
N
P
G
T
K
F
A
I
D
Q
N
Site 182
Y1961
D
F
E
E
M
T
E
Y
E
L
L
I
Q
I
S
Site 183
S1968
Y
E
L
L
I
Q
I
S
D
S
V
H
Y
T
E
Site 184
Y1997
P
V
F
S
Q
D
F
Y
Q
V
T
V
P
E
S
Site 185
T2000
S
Q
D
F
Y
Q
V
T
V
P
E
S
I
P
V
Site 186
S2015
G
Y
S
V
L
T
L
S
A
T
D
L
E
S
N
Site 187
T2017
S
V
L
T
L
S
A
T
D
L
E
S
N
E
N
Site 188
S2021
L
S
A
T
D
L
E
S
N
E
N
I
S
Y
R
Site 189
S2026
L
E
S
N
E
N
I
S
Y
R
I
L
S
S
S
Site 190
Y2027
E
S
N
E
N
I
S
Y
R
I
L
S
S
S
K
Site 191
S2031
N
I
S
Y
R
I
L
S
S
S
K
E
F
S
I
Site 192
S2032
I
S
Y
R
I
L
S
S
S
K
E
F
S
I
D
Site 193
S2033
S
Y
R
I
L
S
S
S
K
E
F
S
I
D
P
Site 194
S2037
L
S
S
S
K
E
F
S
I
D
P
K
N
G
T
Site 195
Y2090
G
I
E
D
M
N
N
Y
A
P
E
F
T
V
K
Site 196
S2098
A
P
E
F
T
V
K
S
Y
N
L
S
L
S
E
Site 197
S2102
T
V
K
S
Y
N
L
S
L
S
E
D
A
L
V
Site 198
S2104
K
S
Y
N
L
S
L
S
E
D
A
L
V
G
S
Site 199
T2124
S
N
I
D
H
D
W
T
R
E
N
T
Y
V
E
Site 200
Y2129
D
W
T
R
E
N
T
Y
V
E
Y
S
I
I
S
Site 201
Y2132
R
E
N
T
Y
V
E
Y
S
I
I
S
G
N
S
Site 202
S2133
E
N
T
Y
V
E
Y
S
I
I
S
G
N
S
Q
Site 203
S2139
Y
S
I
I
S
G
N
S
Q
N
N
F
H
V
E
Site 204
Y2154
T
K
F
F
H
S
E
Y
P
Y
K
Q
V
G
Y
Site 205
Y2156
F
F
H
S
E
Y
P
Y
K
Q
V
G
Y
L
V
Site 206
S2173
H
S
L
D
R
E
A
S
A
S
H
E
L
V
I
Site 207
S2212
D
N
P
P
N
F
S
S
L
S
Y
H
T
H
V
Site 208
S2214
P
P
N
F
S
S
L
S
Y
H
T
H
V
K
E
Site 209
T2223
H
T
H
V
K
E
S
T
P
L
G
S
H
I
T
Site 210
T2230
T
P
L
G
S
H
I
T
V
V
S
A
N
D
R
Site 211
S2233
G
S
H
I
T
V
V
S
A
N
D
R
D
T
G
Site 212
T2239
V
S
A
N
D
R
D
T
G
S
H
A
E
I
I
Site 213
S2241
A
N
D
R
D
T
G
S
H
A
E
I
I
Y
N
Site 214
Y2247
G
S
H
A
E
I
I
Y
N
I
I
S
G
N
E
Site 215
Y2259
G
N
E
K
G
H
F
Y
L
E
E
N
T
G
V
Site 216
Y2268
E
E
N
T
G
V
L
Y
L
I
K
P
L
D
Y
Site 217
Y2275
Y
L
I
K
P
L
D
Y
E
K
M
T
K
F
T
Site 218
T2284
K
M
T
K
F
T
L
T
V
Q
A
S
D
A
E
Site 219
S2288
F
T
L
T
V
Q
A
S
D
A
E
K
K
H
F
Site 220
Y2387
H
A
K
Q
I
L
D
Y
E
N
G
N
K
Y
C
Site 221
Y2393
D
Y
E
N
G
N
K
Y
C
L
T
V
Q
A
K
Site 222
T2396
N
G
N
K
Y
C
L
T
V
Q
A
K
D
K
G
Site 223
Y2430
P
I
F
T
Q
D
Q
Y
F
F
T
L
P
E
K
Site 224
S2468
L
Y
S
L
G
T
S
S
P
F
F
S
V
N
K
Site 225
S2472
G
T
S
S
P
F
F
S
V
N
K
T
N
G
N
Site 226
T2476
P
F
F
S
V
N
K
T
N
G
N
I
Y
L
I
Site 227
Y2481
N
K
T
N
G
N
I
Y
L
I
R
A
L
P
L
Site 228
S2491
R
A
L
P
L
I
K
S
Q
L
N
K
E
D
T
Site 229
T2498
S
Q
L
N
K
E
D
T
L
E
M
K
I
I
A
Site 230
S2507
E
M
K
I
I
A
H
S
P
K
S
D
S
K
F
Site 231
S2510
I
I
A
H
S
P
K
S
D
S
K
F
A
S
C
Site 232
S2512
A
H
S
P
K
S
D
S
K
F
A
S
C
T
V
Site 233
T2569
L
R
H
K
Q
K
D
T
I
N
N
Y
E
E
K
Site 234
Y2573
Q
K
D
T
I
N
N
Y
E
E
K
K
T
S
S
Site 235
T2578
N
N
Y
E
E
K
K
T
S
S
L
D
A
D
L
Site 236
S2580
Y
E
E
K
K
T
S
S
L
D
A
D
L
R
V
Site 237
T2588
L
D
A
D
L
R
V
T
R
D
A
S
V
L
K
Site 238
S2592
L
R
V
T
R
D
A
S
V
L
K
A
F
Q
K
Site 239
T2600
V
L
K
A
F
Q
K
T
D
D
C
S
N
E
V
Site 240
S2604
F
Q
K
T
D
D
C
S
N
E
V
V
P
V
D
Site 241
S2618
D
A
T
P
E
W
L
S
L
I
S
I
M
E
K
Site 242
Y2631
E
K
D
I
V
N
L
Y
R
H
S
N
S
S
G
Site 243
S2634
I
V
N
L
Y
R
H
S
N
S
S
G
H
C
S
Site 244
S2636
N
L
Y
R
H
S
N
S
S
G
H
C
S
V
E
Site 245
S2637
L
Y
R
H
S
N
S
S
G
H
C
S
V
E
G
Site 246
S2641
S
N
S
S
G
H
C
S
V
E
G
E
T
A
E
Site 247
Y2660
Q
R
I
N
E
H
P
Y
R
K
C
S
D
S
A
Site 248
S2664
E
H
P
Y
R
K
C
S
D
S
A
L
S
D
H
Site 249
S2666
P
Y
R
K
C
S
D
S
A
L
S
D
H
E
S
Site 250
S2669
K
C
S
D
S
A
L
S
D
H
E
S
R
V
P
Site 251
S2673
S
A
L
S
D
H
E
S
R
V
P
D
S
G
I
Site 252
S2678
H
E
S
R
V
P
D
S
G
I
P
R
D
S
D
Site 253
S2684
D
S
G
I
P
R
D
S
D
Q
L
S
C
L
S
Site 254
S2688
P
R
D
S
D
Q
L
S
C
L
S
G
E
T
D
Site 255
T2708
E
T
A
E
A
S
Q
T
F
G
E
G
D
Q
G
Site 256
T2731
Q
N
N
V
L
P
Q
T
V
Q
K
R
E
A
K
Site 257
S2740
Q
K
R
E
A
K
E
S
I
L
A
D
V
R
K
Site 258
S2749
L
A
D
V
R
K
E
S
V
F
I
S
G
D
Q
Site 259
S2753
R
K
E
S
V
F
I
S
G
D
Q
E
V
R
C
Site 260
S2764
E
V
R
C
A
A
L
S
T
Q
T
T
S
D
H
Site 261
T2765
V
R
C
A
A
L
S
T
Q
T
T
S
D
H
D
Site 262
T2768
A
A
L
S
T
Q
T
T
S
D
H
D
G
K
D
Site 263
Y2777
D
H
D
G
K
D
N
Y
H
W
N
Y
L
L
S
Site 264
Y2781
K
D
N
Y
H
W
N
Y
L
L
S
W
E
P
K
Site 265
S2794
P
K
F
Q
P
L
A
S
V
F
N
D
I
A
K
Site 266
S2818
G
I
P
K
E
K
K
S
F
V
F
P
P
P
L
Site 267
S2856
V
P
P
K
H
P
R
S
P
I
P
Y
H
L
G
Site 268
Y2860
H
P
R
S
P
I
P
Y
H
L
G
S
L
P
E
Site 269
S2864
P
I
P
Y
H
L
G
S
L
P
E
G
M
T
P
Site 270
T2870
G
S
L
P
E
G
M
T
P
N
F
S
P
S
L
Site 271
S2874
E
G
M
T
P
N
F
S
P
S
L
S
L
L
T
Site 272
S2878
P
N
F
S
P
S
L
S
L
L
T
M
Q
P
P
Site 273
S2888
T
M
Q
P
P
A
L
S
P
L
L
R
E
G
E
Site 274
T2899
R
E
G
E
L
L
G
T
H
I
S
G
T
C
H
Site 275
S2902
E
L
L
G
T
H
I
S
G
T
C
H
E
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation