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Updated November 2019
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Protein Info
Short Name:
ATF7IP
Full Name:
Activating transcription factor 7-interacting protein 1
Alias:
Activating transcription factor 7 interacting protein; ATFa-associated modulator; FLJ10139; FLJ10688; MCAF; MCAF1; P621
Type:
Transcription, coactivator/corepressor
Mass (Da):
136422
Number AA:
1270
UniProt ID:
Q6VMQ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006306
GO:0044419
GO:0045893
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
K
V
F
K
A
R
K
T
M
R
V
S
D
R
Q
Site 2
S21
A
R
K
T
M
R
V
S
D
R
Q
Q
L
E
A
Site 3
T39
V
K
E
E
L
L
K
T
D
V
K
L
L
N
G
Site 4
T56
E
N
G
D
L
D
P
T
S
P
L
E
N
M
D
Site 5
S57
N
G
D
L
D
P
T
S
P
L
E
N
M
D
Y
Site 6
Y64
S
P
L
E
N
M
D
Y
I
K
D
K
E
E
V
Site 7
T91
S
K
A
E
W
K
E
T
P
C
I
L
S
V
N
Site 8
S96
K
E
T
P
C
I
L
S
V
N
V
K
N
K
Q
Site 9
S113
D
L
N
C
E
P
L
S
P
H
N
I
T
P
E
Site 10
T118
P
L
S
P
H
N
I
T
P
E
P
V
S
K
L
Site 11
S123
N
I
T
P
E
P
V
S
K
L
P
A
E
P
V
Site 12
S131
K
L
P
A
E
P
V
S
G
D
P
A
P
G
D
Site 13
S151
P
A
S
G
V
L
A
S
G
D
S
T
S
G
D
Site 14
S154
G
V
L
A
S
G
D
S
T
S
G
D
P
T
S
Site 15
T155
V
L
A
S
G
D
S
T
S
G
D
P
T
S
S
Site 16
S156
L
A
S
G
D
S
T
S
G
D
P
T
S
S
E
Site 17
T160
D
S
T
S
G
D
P
T
S
S
E
P
S
S
S
Site 18
S161
S
T
S
G
D
P
T
S
S
E
P
S
S
S
D
Site 19
S162
T
S
G
D
P
T
S
S
E
P
S
S
S
D
A
Site 20
S165
D
P
T
S
S
E
P
S
S
S
D
A
A
S
G
Site 21
S166
P
T
S
S
E
P
S
S
S
D
A
A
S
G
D
Site 22
S167
T
S
S
E
P
S
S
S
D
A
A
S
G
D
A
Site 23
S171
P
S
S
S
D
A
A
S
G
D
A
T
S
G
D
Site 24
T175
D
A
A
S
G
D
A
T
S
G
D
A
P
S
G
Site 25
S176
A
A
S
G
D
A
T
S
G
D
A
P
S
G
D
Site 26
S181
A
T
S
G
D
A
P
S
G
D
V
S
P
G
D
Site 27
S185
D
A
P
S
G
D
V
S
P
G
D
A
T
S
G
Site 28
T195
D
A
T
S
G
D
A
T
A
D
D
L
S
S
G
Site 29
S200
D
A
T
A
D
D
L
S
S
G
D
P
T
S
S
Site 30
S201
A
T
A
D
D
L
S
S
G
D
P
T
S
S
D
Site 31
T205
D
L
S
S
G
D
P
T
S
S
D
P
I
P
G
Site 32
S206
L
S
S
G
D
P
T
S
S
D
P
I
P
G
E
Site 33
S207
S
S
G
D
P
T
S
S
D
P
I
P
G
E
P
Site 34
S221
P
V
P
V
E
P
I
S
G
D
C
A
A
D
D
Site 35
S246
L
A
S
G
A
P
A
S
T
D
P
A
S
D
D
Site 36
S251
P
A
S
T
D
P
A
S
D
D
L
A
S
G
D
Site 37
S256
P
A
S
D
D
L
A
S
G
D
L
S
S
S
E
Site 38
S260
D
L
A
S
G
D
L
S
S
S
E
L
A
S
D
Site 39
S261
L
A
S
G
D
L
S
S
S
E
L
A
S
D
D
Site 40
S262
A
S
G
D
L
S
S
S
E
L
A
S
D
D
L
Site 41
S266
L
S
S
S
E
L
A
S
D
D
L
A
T
G
E
Site 42
S276
L
A
T
G
E
L
A
S
D
E
L
T
S
E
S
Site 43
T280
E
L
A
S
D
E
L
T
S
E
S
T
F
D
R
Site 44
S283
S
D
E
L
T
S
E
S
T
F
D
R
T
F
E
Site 45
T284
D
E
L
T
S
E
S
T
F
D
R
T
F
E
P
Site 46
T288
S
E
S
T
F
D
R
T
F
E
P
K
S
V
P
Site 47
S293
D
R
T
F
E
P
K
S
V
P
V
C
E
P
V
Site 48
S310
I
D
N
I
E
P
S
S
N
K
D
D
D
F
L
Site 49
S331
E
K
L
E
Q
I
Q
S
K
D
S
L
D
E
K
Site 50
S334
E
Q
I
Q
S
K
D
S
L
D
E
K
N
K
A
Site 51
T354
A
N
E
E
T
L
E
T
D
D
T
T
I
C
S
Site 52
T357
E
T
L
E
T
D
D
T
T
I
C
S
D
R
P
Site 53
T358
T
L
E
T
D
D
T
T
I
C
S
D
R
P
P
Site 54
S361
T
D
D
T
T
I
C
S
D
R
P
P
E
N
E
Site 55
T377
K
V
E
E
D
I
I
T
E
L
A
L
G
E
D
Site 56
S387
A
L
G
E
D
A
I
S
S
S
M
E
I
D
Q
Site 57
S389
G
E
D
A
I
S
S
S
M
E
I
D
Q
G
E
Site 58
T402
G
E
K
N
E
D
E
T
S
A
D
L
V
E
T
Site 59
S403
E
K
N
E
D
E
T
S
A
D
L
V
E
T
I
Site 60
S420
N
V
I
E
D
N
K
S
E
N
I
L
E
N
T
Site 61
S429
N
I
L
E
N
T
D
S
M
E
T
D
E
I
I
Site 62
T450
A
P
S
E
D
E
L
T
C
F
S
K
T
S
L
Site 63
T463
S
L
L
P
I
D
E
T
N
P
D
L
E
E
K
Site 64
S473
D
L
E
E
K
M
E
S
S
F
G
S
P
S
K
Site 65
S474
L
E
E
K
M
E
S
S
F
G
S
P
S
K
Q
Site 66
S477
K
M
E
S
S
F
G
S
P
S
K
Q
E
S
S
Site 67
S479
E
S
S
F
G
S
P
S
K
Q
E
S
S
E
S
Site 68
S483
G
S
P
S
K
Q
E
S
S
E
S
L
P
K
E
Site 69
S484
S
P
S
K
Q
E
S
S
E
S
L
P
K
E
A
Site 70
S486
S
K
Q
E
S
S
E
S
L
P
K
E
A
F
L
Site 71
S496
K
E
A
F
L
V
L
S
D
E
E
D
I
S
G
Site 72
S502
L
S
D
E
E
D
I
S
G
E
K
D
E
S
E
Site 73
S508
I
S
G
E
K
D
E
S
E
V
I
S
Q
N
E
Site 74
S512
K
D
E
S
E
V
I
S
Q
N
E
T
C
S
P
Site 75
T516
E
V
I
S
Q
N
E
T
C
S
P
A
E
V
E
Site 76
S518
I
S
Q
N
E
T
C
S
P
A
E
V
E
S
N
Site 77
S546
H
E
D
D
E
R
P
S
E
K
N
E
F
S
R
Site 78
S552
P
S
E
K
N
E
F
S
R
R
K
R
S
K
S
Site 79
S557
E
F
S
R
R
K
R
S
K
S
E
D
M
D
N
Site 80
S559
S
R
R
K
R
S
K
S
E
D
M
D
N
V
Q
Site 81
Y572
V
Q
S
K
R
R
R
Y
M
E
E
E
Y
E
A
Site 82
Y577
R
R
Y
M
E
E
E
Y
E
A
E
F
Q
V
K
Site 83
T618
Q
C
A
V
F
D
K
T
L
A
E
L
K
T
R
Site 84
T624
K
T
L
A
E
L
K
T
R
V
E
K
I
E
C
Site 85
T637
E
C
N
K
R
H
K
T
V
L
T
E
L
Q
A
Site 86
T650
Q
A
K
I
A
R
L
T
K
R
F
E
A
A
K
Site 87
S673
H
P
P
N
P
P
V
S
P
G
K
T
V
N
D
Site 88
T677
P
P
V
S
P
G
K
T
V
N
D
V
N
S
N
Site 89
T694
M
S
Y
R
N
A
G
T
V
R
Q
M
L
E
S
Site 90
S701
T
V
R
Q
M
L
E
S
K
R
N
V
S
E
S
Site 91
S706
L
E
S
K
R
N
V
S
E
S
A
P
P
S
F
Site 92
S708
S
K
R
N
V
S
E
S
A
P
P
S
F
Q
T
Site 93
S712
V
S
E
S
A
P
P
S
F
Q
T
P
V
N
T
Site 94
T715
S
A
P
P
S
F
Q
T
P
V
N
T
V
S
S
Site 95
T719
S
F
Q
T
P
V
N
T
V
S
S
T
N
L
V
Site 96
S734
T
P
P
A
V
V
S
S
Q
P
K
L
Q
T
P
Site 97
T740
S
S
Q
P
K
L
Q
T
P
V
T
S
G
S
L
Site 98
T743
P
K
L
Q
T
P
V
T
S
G
S
L
T
A
T
Site 99
S769
V
A
T
T
Q
V
P
S
G
N
P
Q
P
T
I
Site 100
T775
P
S
G
N
P
Q
P
T
I
S
L
Q
P
L
P
Site 101
S793
H
V
P
V
A
V
S
S
Q
P
Q
L
L
Q
S
Site 102
S800
S
Q
P
Q
L
L
Q
S
H
P
G
T
L
V
T
Site 103
T804
L
L
Q
S
H
P
G
T
L
V
T
N
Q
P
S
Site 104
T807
S
H
P
G
T
L
V
T
N
Q
P
S
G
N
V
Site 105
S818
S
G
N
V
E
F
I
S
V
Q
S
P
P
T
V
Site 106
T824
I
S
V
Q
S
P
P
T
V
S
G
L
T
K
N
Site 107
S834
G
L
T
K
N
P
V
S
L
P
S
L
P
N
P
Site 108
S837
K
N
P
V
S
L
P
S
L
P
N
P
T
K
P
Site 109
S849
T
K
P
N
N
V
P
S
V
P
S
P
S
I
Q
Site 110
S852
N
N
V
P
S
V
P
S
P
S
I
Q
R
N
P
Site 111
S854
V
P
S
V
P
S
P
S
I
Q
R
N
P
T
A
Site 112
T860
P
S
I
Q
R
N
P
T
A
S
A
A
P
L
G
Site 113
S862
I
Q
R
N
P
T
A
S
A
A
P
L
G
T
T
Site 114
T891
A
T
R
T
S
L
P
T
V
G
P
S
G
L
Y
Site 115
S895
S
L
P
T
V
G
P
S
G
L
Y
S
P
S
T
Site 116
S899
V
G
P
S
G
L
Y
S
P
S
T
N
R
G
P
Site 117
S901
P
S
G
L
Y
S
P
S
T
N
R
G
P
I
Q
Site 118
T902
S
G
L
Y
S
P
S
T
N
R
G
P
I
Q
M
Site 119
S917
K
I
P
I
S
A
F
S
T
S
S
A
A
E
Q
Site 120
T918
I
P
I
S
A
F
S
T
S
S
A
A
E
Q
N
Site 121
S920
I
S
A
F
S
T
S
S
A
A
E
Q
N
S
N
Site 122
T928
A
A
E
Q
N
S
N
T
T
P
R
I
E
N
Q
Site 123
T929
A
E
Q
N
S
N
T
T
P
R
I
E
N
Q
T
Site 124
T936
T
P
R
I
E
N
Q
T
N
K
T
I
D
A
S
Site 125
T939
I
E
N
Q
T
N
K
T
I
D
A
S
V
S
K
Site 126
S943
T
N
K
T
I
D
A
S
V
S
K
K
A
A
D
Site 127
S951
V
S
K
K
A
A
D
S
T
S
Q
C
G
K
A
Site 128
S953
K
K
A
A
D
S
T
S
Q
C
G
K
A
T
G
Site 129
T959
T
S
Q
C
G
K
A
T
G
S
D
S
S
G
V
Site 130
S961
Q
C
G
K
A
T
G
S
D
S
S
G
V
I
D
Site 131
S963
G
K
A
T
G
S
D
S
S
G
V
I
D
L
T
Site 132
T970
S
S
G
V
I
D
L
T
M
D
D
E
E
S
G
Site 133
S976
L
T
M
D
D
E
E
S
G
A
S
Q
D
P
K
Site 134
S979
D
D
E
E
S
G
A
S
Q
D
P
K
K
L
N
Site 135
T988
D
P
K
K
L
N
H
T
P
V
S
T
M
S
S
Site 136
S991
K
L
N
H
T
P
V
S
T
M
S
S
S
Q
P
Site 137
T992
L
N
H
T
P
V
S
T
M
S
S
S
Q
P
V
Site 138
S994
H
T
P
V
S
T
M
S
S
S
Q
P
V
S
R
Site 139
S995
T
P
V
S
T
M
S
S
S
Q
P
V
S
R
P
Site 140
S996
P
V
S
T
M
S
S
S
Q
P
V
S
R
P
L
Site 141
S1000
M
S
S
S
Q
P
V
S
R
P
L
Q
P
I
Q
Site 142
S1015
P
A
P
P
L
Q
P
S
G
V
P
T
S
G
P
Site 143
T1019
L
Q
P
S
G
V
P
T
S
G
P
S
Q
T
T
Site 144
S1020
Q
P
S
G
V
P
T
S
G
P
S
Q
T
T
I
Site 145
T1035
H
L
L
P
T
A
P
T
T
V
N
V
T
H
R
Site 146
T1036
L
L
P
T
A
P
T
T
V
N
V
T
H
R
P
Site 147
T1040
A
P
T
T
V
N
V
T
H
R
P
V
T
Q
V
Site 148
T1045
N
V
T
H
R
P
V
T
Q
V
T
T
R
L
P
Site 149
T1065
A
N
H
Q
V
V
Y
T
T
L
P
A
P
P
A
Site 150
S1094
R
Q
V
N
P
Q
N
S
V
T
V
R
V
P
Q
Site 151
T1096
V
N
P
Q
N
S
V
T
V
R
V
P
Q
T
T
Site 152
T1103
T
V
R
V
P
Q
T
T
T
Y
V
V
N
N
G
Site 153
Y1105
R
V
P
Q
T
T
T
Y
V
V
N
N
G
L
T
Site 154
T1121
G
S
T
G
P
Q
L
T
V
H
H
R
P
P
Q
Site 155
T1131
H
R
P
P
Q
V
H
T
E
P
P
R
P
V
H
Site 156
T1158
L
P
P
E
A
A
S
T
S
L
P
Q
K
P
H
Site 157
S1159
P
P
E
A
A
S
T
S
L
P
Q
K
P
H
L
Site 158
S1189
S
V
L
E
V
D
R
S
C
A
T
V
D
S
Y
Site 159
T1192
E
V
D
R
S
C
A
T
V
D
S
Y
H
L
Y
Site 160
Y1196
S
C
A
T
V
D
S
Y
H
L
Y
A
Y
H
E
Site 161
Y1199
T
V
D
S
Y
H
L
Y
A
Y
H
E
E
P
S
Site 162
Y1201
D
S
Y
H
L
Y
A
Y
H
E
E
P
S
A
T
Site 163
T1208
Y
H
E
E
P
S
A
T
V
P
S
Q
W
K
K
Site 164
S1211
E
P
S
A
T
V
P
S
Q
W
K
K
I
G
E
Site 165
Y1239
Q
F
V
S
G
S
K
Y
Y
F
A
V
R
A
K
Site 166
Y1240
F
V
S
G
S
K
Y
Y
F
A
V
R
A
K
D
Site 167
Y1249
A
V
R
A
K
D
I
Y
G
R
F
G
P
F
C
Site 168
S1260
G
P
F
C
D
P
Q
S
T
D
V
I
S
S
T
Site 169
T1261
P
F
C
D
P
Q
S
T
D
V
I
S
S
T
Q
Site 170
S1265
P
Q
S
T
D
V
I
S
S
T
Q
S
S
_
_
Site 171
S1266
Q
S
T
D
V
I
S
S
T
Q
S
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation