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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RanBP10
Full Name:
Ran-binding protein 10
Alias:
KIAA1464; RAN binding protein 10; Ran-binding protein 10; RBP10
Type:
GTPase activating protein, Ras; Guanine nucleotide exchange factor, Ras
Mass (Da):
67257
Number AA:
620
UniProt ID:
Q6VN20
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
G
N
P
Q
P
G
D
S
S
G
G
G
A
G
G
Site 2
S19
N
P
Q
P
G
D
S
S
G
G
G
A
G
G
G
Site 3
S29
G
A
G
G
G
L
P
S
P
G
E
Q
E
L
S
Site 4
S36
S
P
G
E
Q
E
L
S
R
R
L
Q
R
L
Y
Site 5
Y43
S
R
R
L
Q
R
L
Y
P
A
V
N
Q
Q
E
Site 6
T51
P
A
V
N
Q
Q
E
T
P
L
P
R
S
W
S
Site 7
S56
Q
E
T
P
L
P
R
S
W
S
P
K
D
K
Y
Site 8
S58
T
P
L
P
R
S
W
S
P
K
D
K
Y
N
Y
Site 9
Y63
S
W
S
P
K
D
K
Y
N
Y
I
G
L
S
Q
Site 10
Y65
S
P
K
D
K
Y
N
Y
I
G
L
S
Q
G
N
Site 11
S69
K
Y
N
Y
I
G
L
S
Q
G
N
L
R
V
H
Site 12
Y77
Q
G
N
L
R
V
H
Y
K
G
H
G
K
N
H
Site 13
S89
K
N
H
K
D
A
A
S
V
R
A
T
H
P
I
Site 14
Y117
V
S
K
G
R
D
G
Y
M
G
I
G
L
S
A
Site 15
Y140
P
G
W
D
K
H
S
Y
G
Y
H
G
D
D
G
Site 16
S149
Y
H
G
D
D
G
H
S
F
C
S
S
G
T
G
Site 17
S153
D
G
H
S
F
C
S
S
G
T
G
Q
P
Y
G
Site 18
Y159
S
S
G
T
G
Q
P
Y
G
P
T
F
T
T
G
Site 19
T162
T
G
Q
P
Y
G
P
T
F
T
T
G
D
V
I
Site 20
Y182
L
I
N
G
T
C
F
Y
T
K
N
G
H
S
L
Site 21
Y201
T
D
L
P
A
N
L
Y
P
T
V
G
L
Q
T
Site 22
Y229
F
L
F
D
I
E
D
Y
M
R
E
W
R
A
K
Site 23
T281
A
T
A
F
A
R
M
T
E
T
P
I
Q
E
E
Site 24
T283
A
F
A
R
M
T
E
T
P
I
Q
E
E
Q
A
Site 25
S291
P
I
Q
E
E
Q
A
S
I
K
N
R
Q
K
I
Site 26
T313
R
V
G
E
A
I
E
T
T
Q
R
F
Y
P
G
Site 27
T314
V
G
E
A
I
E
T
T
Q
R
F
Y
P
G
L
Site 28
Y318
I
E
T
T
Q
R
F
Y
P
G
L
L
E
H
N
Site 29
S346
E
M
V
N
G
T
D
S
E
V
R
S
L
S
S
Site 30
S350
G
T
D
S
E
V
R
S
L
S
S
R
S
P
K
Site 31
S352
D
S
E
V
R
S
L
S
S
R
S
P
K
S
Q
Site 32
S353
S
E
V
R
S
L
S
S
R
S
P
K
S
Q
D
Site 33
S355
V
R
S
L
S
S
R
S
P
K
S
Q
D
S
Y
Site 34
S358
L
S
S
R
S
P
K
S
Q
D
S
Y
P
G
S
Site 35
S361
R
S
P
K
S
Q
D
S
Y
P
G
S
P
S
L
Site 36
Y362
S
P
K
S
Q
D
S
Y
P
G
S
P
S
L
S
Site 37
S365
S
Q
D
S
Y
P
G
S
P
S
L
S
P
R
H
Site 38
S367
D
S
Y
P
G
S
P
S
L
S
P
R
H
G
P
Site 39
S369
Y
P
G
S
P
S
L
S
P
R
H
G
P
S
S
Site 40
S375
L
S
P
R
H
G
P
S
S
S
H
M
H
N
T
Site 41
S376
S
P
R
H
G
P
S
S
S
H
M
H
N
T
G
Site 42
S377
P
R
H
G
P
S
S
S
H
M
H
N
T
G
A
Site 43
T382
S
S
S
H
M
H
N
T
G
A
D
S
P
S
C
Site 44
S386
M
H
N
T
G
A
D
S
P
S
C
S
N
G
V
Site 45
S388
N
T
G
A
D
S
P
S
C
S
N
G
V
A
S
Site 46
S390
G
A
D
S
P
S
C
S
N
G
V
A
S
T
K
Site 47
S398
N
G
V
A
S
T
K
S
K
Q
N
H
S
K
Y
Site 48
S403
T
K
S
K
Q
N
H
S
K
Y
P
A
P
S
S
Site 49
Y405
S
K
Q
N
H
S
K
Y
P
A
P
S
S
S
S
Site 50
S409
H
S
K
Y
P
A
P
S
S
S
S
S
S
S
S
Site 51
S410
S
K
Y
P
A
P
S
S
S
S
S
S
S
S
S
Site 52
S411
K
Y
P
A
P
S
S
S
S
S
S
S
S
S
S
Site 53
S412
Y
P
A
P
S
S
S
S
S
S
S
S
S
S
S
Site 54
S413
P
A
P
S
S
S
S
S
S
S
S
S
S
S
S
Site 55
S414
A
P
S
S
S
S
S
S
S
S
S
S
S
S
S
Site 56
S415
P
S
S
S
S
S
S
S
S
S
S
S
S
S
S
Site 57
S416
S
S
S
S
S
S
S
S
S
S
S
S
S
S
P
Site 58
S417
S
S
S
S
S
S
S
S
S
S
S
S
S
P
S
Site 59
S418
S
S
S
S
S
S
S
S
S
S
S
S
P
S
S
Site 60
S419
S
S
S
S
S
S
S
S
S
S
S
P
S
S
V
Site 61
S420
S
S
S
S
S
S
S
S
S
S
P
S
S
V
N
Site 62
S421
S
S
S
S
S
S
S
S
S
P
S
S
V
N
Y
Site 63
S422
S
S
S
S
S
S
S
S
P
S
S
V
N
Y
S
Site 64
S424
S
S
S
S
S
S
P
S
S
V
N
Y
S
E
S
Site 65
S425
S
S
S
S
S
P
S
S
V
N
Y
S
E
S
N
Site 66
Y428
S
S
P
S
S
V
N
Y
S
E
S
N
S
T
D
Site 67
S429
S
P
S
S
V
N
Y
S
E
S
N
S
T
D
S
Site 68
S431
S
S
V
N
Y
S
E
S
N
S
T
D
S
T
K
Site 69
S433
V
N
Y
S
E
S
N
S
T
D
S
T
K
S
Q
Site 70
T434
N
Y
S
E
S
N
S
T
D
S
T
K
S
Q
H
Site 71
S436
S
E
S
N
S
T
D
S
T
K
S
Q
H
H
S
Site 72
T437
E
S
N
S
T
D
S
T
K
S
Q
H
H
S
S
Site 73
S439
N
S
T
D
S
T
K
S
Q
H
H
S
S
T
S
Site 74
S443
S
T
K
S
Q
H
H
S
S
T
S
N
Q
E
T
Site 75
S444
T
K
S
Q
H
H
S
S
T
S
N
Q
E
T
S
Site 76
T450
S
S
T
S
N
Q
E
T
S
D
S
E
M
E
M
Site 77
S451
S
T
S
N
Q
E
T
S
D
S
E
M
E
M
E
Site 78
S453
S
N
Q
E
T
S
D
S
E
M
E
M
E
A
E
Site 79
Y462
M
E
M
E
A
E
H
Y
P
N
G
V
L
G
S
Site 80
S469
Y
P
N
G
V
L
G
S
M
S
T
R
I
V
N
Site 81
T486
Y
K
H
E
D
L
Q
T
D
E
S
S
M
D
D
Site 82
S489
E
D
L
Q
T
D
E
S
S
M
D
D
R
H
P
Site 83
S490
D
L
Q
T
D
E
S
S
M
D
D
R
H
P
R
Site 84
S522
G
R
E
L
Q
A
L
S
E
Q
L
G
R
E
Y
Site 85
Y529
S
E
Q
L
G
R
E
Y
G
K
N
L
A
H
T
Site 86
S544
E
M
L
Q
D
A
F
S
L
L
A
Y
S
D
P
Site 87
Y548
D
A
F
S
L
L
A
Y
S
D
P
W
S
C
P
Site 88
S553
L
A
Y
S
D
P
W
S
C
P
V
G
Q
Q
L
Site 89
S611
R
A
G
L
G
S
C
S
F
A
R
V
D
D
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation