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Updated November 2019
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Protein Info
Short Name:
Rab11FIP1
Full Name:
Rab11 family-interacting protein 1
Alias:
FLJ22524; FLJ22622; NOEL1A; RAB11 coupling protein; RAB11 family interacting protein 1; Rab11-FIP1; Rab-coupling protein; RCP; RFIP1
Type:
Vesicle protein
Mass (Da):
137195
Number AA:
1283
UniProt ID:
Q6WKZ4
International Prot ID:
IPI00419433
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030670
GO:0055037
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y42
P
G
G
T
S
D
A
Y
A
V
I
Q
V
G
K
Site 2
Y52
I
Q
V
G
K
E
K
Y
A
T
S
V
S
E
R
Site 3
T54
V
G
K
E
K
Y
A
T
S
V
S
E
R
S
L
Site 4
S55
G
K
E
K
Y
A
T
S
V
S
E
R
S
L
G
Site 5
S57
E
K
Y
A
T
S
V
S
E
R
S
L
G
A
P
Site 6
S60
A
T
S
V
S
E
R
S
L
G
A
P
V
W
R
Site 7
T71
P
V
W
R
E
E
A
T
F
E
L
P
S
L
L
Site 8
T123
R
D
Q
G
R
R
K
T
Q
W
Y
K
L
K
S
Site 9
Y126
G
R
R
K
T
Q
W
Y
K
L
K
S
K
P
G
Site 10
S130
T
Q
W
Y
K
L
K
S
K
P
G
K
K
D
K
Site 11
T154
Q
F
M
R
N
N
M
T
A
S
M
F
D
L
S
Site 12
S156
M
R
N
N
M
T
A
S
M
F
D
L
S
M
K
Site 13
S161
T
A
S
M
F
D
L
S
M
K
D
K
S
R
N
Site 14
S166
D
L
S
M
K
D
K
S
R
N
P
F
G
K
L
Site 15
S184
I
K
G
K
N
K
D
S
G
S
D
T
A
S
A
Site 16
S186
G
K
N
K
D
S
G
S
D
T
A
S
A
I
I
Site 17
T188
N
K
D
S
G
S
D
T
A
S
A
I
I
P
S
Site 18
S190
D
S
G
S
D
T
A
S
A
I
I
P
S
T
T
Site 19
T196
A
S
A
I
I
P
S
T
T
P
S
V
D
S
D
Site 20
T197
S
A
I
I
P
S
T
T
P
S
V
D
S
D
D
Site 21
S199
I
I
P
S
T
T
P
S
V
D
S
D
D
E
S
Site 22
S202
S
T
T
P
S
V
D
S
D
D
E
S
V
V
K
Site 23
S206
S
V
D
S
D
D
E
S
V
V
K
D
K
K
K
Site 24
S215
V
K
D
K
K
K
K
S
K
I
K
T
L
L
S
Site 25
T219
K
K
K
S
K
I
K
T
L
L
S
K
S
N
L
Site 26
S222
S
K
I
K
T
L
L
S
K
S
N
L
Q
K
T
Site 27
S224
I
K
T
L
L
S
K
S
N
L
Q
K
T
P
L
Site 28
T229
S
K
S
N
L
Q
K
T
P
L
S
Q
S
M
S
Site 29
S232
N
L
Q
K
T
P
L
S
Q
S
M
S
V
L
P
Site 30
S234
Q
K
T
P
L
S
Q
S
M
S
V
L
P
T
S
Site 31
S236
T
P
L
S
Q
S
M
S
V
L
P
T
S
K
P
Site 32
T240
Q
S
M
S
V
L
P
T
S
K
P
E
K
V
L
Site 33
S255
L
R
P
G
D
F
Q
S
Q
W
D
E
D
D
N
Site 34
S266
E
D
D
N
E
D
E
S
S
S
A
S
D
V
M
Site 35
S267
D
D
N
E
D
E
S
S
S
A
S
D
V
M
S
Site 36
S268
D
N
E
D
E
S
S
S
A
S
D
V
M
S
H
Site 37
S270
E
D
E
S
S
S
A
S
D
V
M
S
H
K
R
Site 38
S274
S
S
A
S
D
V
M
S
H
K
R
T
A
S
T
Site 39
T278
D
V
M
S
H
K
R
T
A
S
T
D
L
K
Q
Site 40
S280
M
S
H
K
R
T
A
S
T
D
L
K
Q
L
N
Site 41
T281
S
H
K
R
T
A
S
T
D
L
K
Q
L
N
Q
Site 42
S300
L
P
K
K
E
G
L
S
F
L
G
G
L
R
S
Site 43
S307
S
F
L
G
G
L
R
S
K
N
D
V
L
S
R
Site 44
S313
R
S
K
N
D
V
L
S
R
S
N
V
C
I
N
Site 45
Y325
C
I
N
G
N
H
V
Y
L
E
Q
P
E
A
K
Site 46
S338
A
K
G
E
I
K
D
S
S
P
S
S
S
P
S
Site 47
S339
K
G
E
I
K
D
S
S
P
S
S
S
P
S
P
Site 48
S341
E
I
K
D
S
S
P
S
S
S
P
S
P
K
G
Site 49
S342
I
K
D
S
S
P
S
S
S
P
S
P
K
G
F
Site 50
S343
K
D
S
S
P
S
S
S
P
S
P
K
G
F
R
Site 51
S345
S
S
P
S
S
S
P
S
P
K
G
F
R
K
K
Site 52
S356
F
R
K
K
H
L
F
S
S
T
E
N
L
A
A
Site 53
S357
R
K
K
H
L
F
S
S
T
E
N
L
A
A
G
Site 54
T358
K
K
H
L
F
S
S
T
E
N
L
A
A
G
S
Site 55
S365
T
E
N
L
A
A
G
S
W
K
E
P
A
E
G
Site 56
S376
P
A
E
G
G
G
L
S
S
D
R
Q
L
S
E
Site 57
S377
A
E
G
G
G
L
S
S
D
R
Q
L
S
E
S
Site 58
S382
L
S
S
D
R
Q
L
S
E
S
S
T
K
D
S
Site 59
S384
S
D
R
Q
L
S
E
S
S
T
K
D
S
L
K
Site 60
S385
D
R
Q
L
S
E
S
S
T
K
D
S
L
K
S
Site 61
T386
R
Q
L
S
E
S
S
T
K
D
S
L
K
S
M
Site 62
S389
S
E
S
S
T
K
D
S
L
K
S
M
T
L
P
Site 63
S392
S
T
K
D
S
L
K
S
M
T
L
P
S
Y
R
Site 64
T394
K
D
S
L
K
S
M
T
L
P
S
Y
R
P
A
Site 65
Y398
K
S
M
T
L
P
S
Y
R
P
A
P
L
V
S
Site 66
S426
A
T
K
E
A
K
E
S
K
K
P
E
S
R
R
Site 67
S431
K
E
S
K
K
P
E
S
R
R
S
S
L
L
S
Site 68
S434
K
K
P
E
S
R
R
S
S
L
L
S
L
M
T
Site 69
S435
K
P
E
S
R
R
S
S
L
L
S
L
M
T
G
Site 70
S438
S
R
R
S
S
L
L
S
L
M
T
G
K
K
D
Site 71
T441
S
S
L
L
S
L
M
T
G
K
K
D
V
A
K
Site 72
T457
S
E
G
E
N
P
L
T
V
P
G
R
E
K
E
Site 73
S477
V
K
P
G
E
D
A
S
G
P
A
E
D
L
V
Site 74
S487
A
E
D
L
V
R
R
S
E
K
D
T
A
A
V
Site 75
T491
V
R
R
S
E
K
D
T
A
A
V
V
S
R
Q
Site 76
S496
K
D
T
A
A
V
V
S
R
Q
G
S
S
L
N
Site 77
S500
A
V
V
S
R
Q
G
S
S
L
N
L
F
E
D
Site 78
S501
V
V
S
R
Q
G
S
S
L
N
L
F
E
D
V
Site 79
S519
E
P
E
A
E
P
E
S
K
S
E
P
R
P
P
Site 80
S521
E
A
E
P
E
S
K
S
E
P
R
P
P
I
S
Site 81
S528
S
E
P
R
P
P
I
S
S
P
R
A
P
Q
T
Site 82
S529
E
P
R
P
P
I
S
S
P
R
A
P
Q
T
R
Site 83
T535
S
S
P
R
A
P
Q
T
R
A
V
K
P
R
L
Site 84
S545
V
K
P
R
L
E
V
S
P
E
A
Q
P
T
A
Site 85
T551
V
S
P
E
A
Q
P
T
A
R
L
P
S
P
T
Site 86
S556
Q
P
T
A
R
L
P
S
P
T
D
S
P
S
S
Site 87
T558
T
A
R
L
P
S
P
T
D
S
P
S
S
L
P
Site 88
S560
R
L
P
S
P
T
D
S
P
S
S
L
P
P
L
Site 89
S562
P
S
P
T
D
S
P
S
S
L
P
P
L
P
S
Site 90
S563
S
P
T
D
S
P
S
S
L
P
P
L
P
S
S
Site 91
S569
S
S
L
P
P
L
P
S
S
S
G
Q
A
S
V
Site 92
S570
S
L
P
P
L
P
S
S
S
G
Q
A
S
V
P
Site 93
S571
L
P
P
L
P
S
S
S
G
Q
A
S
V
P
S
Site 94
S575
P
S
S
S
G
Q
A
S
V
P
S
E
L
G
H
Site 95
S578
S
G
Q
A
S
V
P
S
E
L
G
H
G
A
D
Site 96
T586
E
L
G
H
G
A
D
T
Q
S
S
E
S
P
S
Site 97
S588
G
H
G
A
D
T
Q
S
S
E
S
P
S
V
F
Site 98
S589
H
G
A
D
T
Q
S
S
E
S
P
S
V
F
S
Site 99
S591
A
D
T
Q
S
S
E
S
P
S
V
F
S
S
L
Site 100
S593
T
Q
S
S
E
S
P
S
V
F
S
S
L
S
S
Site 101
S596
S
E
S
P
S
V
F
S
S
L
S
S
P
I
A
Site 102
S614
S
T
S
T
P
I
E
S
W
P
L
V
D
R
G
Site 103
S625
V
D
R
G
K
A
K
S
E
G
P
P
L
L
P
Site 104
S640
K
A
E
L
Q
T
E
S
L
T
P
V
P
N
S
Site 105
T642
E
L
Q
T
E
S
L
T
P
V
P
N
S
G
S
Site 106
S647
S
L
T
P
V
P
N
S
G
S
S
V
L
G
S
Site 107
S654
S
G
S
S
V
L
G
S
L
F
K
Q
P
S
F
Site 108
S660
G
S
L
F
K
Q
P
S
F
P
A
N
K
G
T
Site 109
S670
A
N
K
G
T
E
D
S
L
M
G
R
T
R
E
Site 110
T678
L
M
G
R
T
R
E
T
G
T
E
K
N
T
S
Site 111
T684
E
T
G
T
E
K
N
T
S
S
L
E
L
E
E
Site 112
S685
T
G
T
E
K
N
T
S
S
L
E
L
E
E
S
Site 113
S686
G
T
E
K
N
T
S
S
L
E
L
E
E
S
L
Site 114
S692
S
S
L
E
L
E
E
S
L
P
E
Q
P
E
T
Site 115
T699
S
L
P
E
Q
P
E
T
G
R
Q
E
E
E
L
Site 116
Y716
F
P
C
K
K
Q
D
Y
S
P
S
S
G
E
A
Site 117
S717
P
C
K
K
Q
D
Y
S
P
S
S
G
E
A
Q
Site 118
S720
K
Q
D
Y
S
P
S
S
G
E
A
Q
E
V
P
Site 119
S754
G
G
D
R
D
L
E
S
Q
A
G
S
L
V
E
Site 120
S758
D
L
E
S
Q
A
G
S
L
V
E
S
K
A
R
Site 121
S762
Q
A
G
S
L
V
E
S
K
A
R
D
A
A
E
Site 122
S783
P
M
G
A
S
V
P
S
I
D
S
M
M
R
K
Site 123
S786
A
S
V
P
S
I
D
S
M
M
R
K
L
E
E
Site 124
T805
L
R
K
D
Q
K
K
T
K
K
R
V
S
F
S
Site 125
S810
K
K
T
K
K
R
V
S
F
S
E
Q
L
F
T
Site 126
S812
T
K
K
R
V
S
F
S
E
Q
L
F
T
E
E
Site 127
S832
A
L
L
V
E
G
H
S
S
C
P
Q
E
L
N
Site 128
S833
L
L
V
E
G
H
S
S
C
P
Q
E
L
N
P
Site 129
S843
Q
E
L
N
P
A
W
S
V
A
G
N
A
S
D
Site 130
S849
W
S
V
A
G
N
A
S
D
G
E
P
P
E
S
Site 131
S856
S
D
G
E
P
P
E
S
P
H
A
E
D
S
E
Site 132
S862
E
S
P
H
A
E
D
S
E
R
E
S
V
T
T
Site 133
S866
A
E
D
S
E
R
E
S
V
T
T
P
G
P
A
Site 134
T869
S
E
R
E
S
V
T
T
P
G
P
A
T
C
G
Site 135
S880
A
T
C
G
A
P
A
S
P
A
D
H
L
L
L
Site 136
S889
A
D
H
L
L
L
P
S
Q
E
E
S
F
S
E
Site 137
S893
L
L
P
S
Q
E
E
S
F
S
E
V
P
M
S
Site 138
S895
P
S
Q
E
E
S
F
S
E
V
P
M
S
E
A
Site 139
S900
S
F
S
E
V
P
M
S
E
A
S
S
A
K
D
Site 140
S904
V
P
M
S
E
A
S
S
A
K
D
T
P
L
F
Site 141
T908
E
A
S
S
A
K
D
T
P
L
F
R
M
E
G
Site 142
T921
E
G
E
D
A
L
V
T
Q
Y
Q
S
K
A
S
Site 143
Y923
E
D
A
L
V
T
Q
Y
Q
S
K
A
S
D
H
Site 144
S935
S
D
H
E
G
L
L
S
D
P
L
S
D
L
Q
Site 145
S949
Q
L
V
S
D
F
K
S
P
I
M
A
D
L
N
Site 146
S967
P
S
I
P
E
V
A
S
D
D
E
R
I
D
Q
Site 147
T988
Q
V
E
D
D
G
E
T
A
K
S
S
T
L
D
Site 148
S991
D
D
G
E
T
A
K
S
S
T
L
D
I
G
A
Site 149
S992
D
G
E
T
A
K
S
S
T
L
D
I
G
A
L
Site 150
S1015
P
E
R
G
K
G
P
S
G
E
A
D
R
L
V
Site 151
S1038
R
L
Q
A
P
Q
A
S
V
T
A
P
S
E
Q
Site 152
T1047
T
A
P
S
E
Q
T
T
E
F
G
I
H
K
P
Site 153
S1059
H
K
P
H
L
G
K
S
S
S
L
D
K
Q
L
Site 154
S1061
P
H
L
G
K
S
S
S
L
D
K
Q
L
P
G
Site 155
S1082
E
K
P
M
G
N
G
S
P
S
P
P
P
G
T
Site 156
S1084
P
M
G
N
G
S
P
S
P
P
P
G
T
S
L
Site 157
T1089
S
P
S
P
P
P
G
T
S
L
D
N
P
V
P
Site 158
S1090
P
S
P
P
P
G
T
S
L
D
N
P
V
P
S
Site 159
S1097
S
L
D
N
P
V
P
S
P
S
P
S
E
I
F
Site 160
S1099
D
N
P
V
P
S
P
S
P
S
E
I
F
P
V
Site 161
S1101
P
V
P
S
P
S
P
S
E
I
F
P
V
T
H
Site 162
T1107
P
S
E
I
F
P
V
T
H
S
F
P
S
S
A
Site 163
S1109
E
I
F
P
V
T
H
S
F
P
S
S
A
H
S
Site 164
S1112
P
V
T
H
S
F
P
S
S
A
H
S
D
T
H
Site 165
S1113
V
T
H
S
F
P
S
S
A
H
S
D
T
H
H
Site 166
S1116
S
F
P
S
S
A
H
S
D
T
H
H
T
S
T
Site 167
T1118
P
S
S
A
H
S
D
T
H
H
T
S
T
A
E
Site 168
S1122
H
S
D
T
H
H
T
S
T
A
E
S
Q
K
K
Site 169
S1126
H
H
T
S
T
A
E
S
Q
K
K
A
T
A
E
Site 170
S1135
K
K
A
T
A
E
G
S
A
G
R
V
E
N
F
Site 171
S1154
P
L
L
Q
A
W
V
S
P
S
E
T
H
P
V
Site 172
S1156
L
Q
A
W
V
S
P
S
E
T
H
P
V
S
A
Site 173
T1158
A
W
V
S
P
S
E
T
H
P
V
S
A
Q
P
Site 174
S1162
P
S
E
T
H
P
V
S
A
Q
P
G
A
G
T
Site 175
S1171
Q
P
G
A
G
T
G
S
A
K
H
R
L
H
P
Site 176
T1187
K
P
M
N
A
M
A
T
K
V
A
N
C
S
L
Site 177
Y1213
N
E
V
M
M
K
K
Y
S
P
S
D
P
A
F
Site 178
S1214
E
V
M
M
K
K
Y
S
P
S
D
P
A
F
A
Site 179
S1216
M
M
K
K
Y
S
P
S
D
P
A
F
A
Y
A
Site 180
T1226
A
F
A
Y
A
Q
L
T
H
D
E
L
I
Q
L
Site 181
S1242
L
K
Q
K
E
T
I
S
K
K
E
F
Q
V
R
Site 182
Y1254
Q
V
R
E
L
E
D
Y
I
D
N
L
L
V
R
Site 183
T1274
P
N
I
L
R
I
P
T
Q
V
G
K
K
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation