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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NELF
Full Name:
Nasal embryonic luteinizing hormone-releasing hormone factor
Alias:
MGC125369; nasal embryonic LHRH factor; RP11-48C7.1
Type:
Mass (Da):
60143
Number AA:
530
UniProt ID:
Q6X4W1
International Prot ID:
IPI00450993
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
GO:0005634
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
A
A
A
S
R
R
R
A
L
R
S
Site 2
S13
S
R
R
R
A
L
R
S
E
A
M
S
S
V
A
Site 3
S17
A
L
R
S
E
A
M
S
S
V
A
A
K
V
R
Site 4
S18
L
R
S
E
A
M
S
S
V
A
A
K
V
R
A
Site 5
Y32
A
A
R
A
F
G
E
Y
L
S
Q
S
H
P
E
Site 6
S34
R
A
F
G
E
Y
L
S
Q
S
H
P
E
N
R
Site 7
S36
F
G
E
Y
L
S
Q
S
H
P
E
N
R
N
G
Site 8
Y52
D
H
L
L
A
D
A
Y
S
G
H
D
G
S
P
Site 9
S53
H
L
L
A
D
A
Y
S
G
H
D
G
S
P
E
Site 10
S58
A
Y
S
G
H
D
G
S
P
E
M
Q
P
A
P
Site 11
S72
P
Q
N
K
R
R
L
S
L
V
S
N
G
C
Y
Site 12
S75
K
R
R
L
S
L
V
S
N
G
C
Y
E
G
S
Site 13
Y79
S
L
V
S
N
G
C
Y
E
G
S
L
S
E
E
Site 14
S82
S
N
G
C
Y
E
G
S
L
S
E
E
P
S
I
Site 15
S84
G
C
Y
E
G
S
L
S
E
E
P
S
I
R
K
Site 16
S88
G
S
L
S
E
E
P
S
I
R
K
P
A
G
E
Site 17
Y102
E
G
P
Q
P
R
V
Y
T
I
S
G
E
P
A
Site 18
T103
G
P
Q
P
R
V
Y
T
I
S
G
E
P
A
L
Site 19
S105
Q
P
R
V
Y
T
I
S
G
E
P
A
L
L
P
Site 20
S113
G
E
P
A
L
L
P
S
P
E
A
E
A
I
E
Site 21
S136
Q
R
H
P
H
H
H
S
Q
P
L
R
A
S
P
Site 22
S142
H
S
Q
P
L
R
A
S
P
G
G
S
R
E
D
Site 23
S146
L
R
A
S
P
G
G
S
R
E
D
V
S
R
P
Site 24
S151
G
G
S
R
E
D
V
S
R
P
C
Q
S
W
A
Site 25
S156
D
V
S
R
P
C
Q
S
W
A
G
S
R
Q
G
Site 26
S160
P
C
Q
S
W
A
G
S
R
Q
G
S
K
E
C
Site 27
S164
W
A
G
S
R
Q
G
S
K
E
C
P
G
C
A
Site 28
T178
A
Q
L
A
P
G
P
T
P
R
A
F
G
L
D
Site 29
S193
Q
P
P
L
P
E
T
S
G
R
R
K
K
L
E
Site 30
Y203
R
K
K
L
E
R
M
Y
S
V
D
R
V
S
D
Site 31
S204
K
K
L
E
R
M
Y
S
V
D
R
V
S
D
D
Site 32
S209
M
Y
S
V
D
R
V
S
D
D
I
P
I
R
T
Site 33
T216
S
D
D
I
P
I
R
T
W
F
P
K
E
N
L
Site 34
S225
F
P
K
E
N
L
F
S
F
Q
T
A
T
T
T
Site 35
Y242
A
I
S
V
F
R
G
Y
A
E
R
K
R
R
K
Site 36
S254
R
R
K
R
E
N
D
S
A
S
V
I
Q
R
N
Site 37
S256
K
R
E
N
D
S
A
S
V
I
Q
R
N
F
R
Site 38
S271
K
H
L
R
M
V
G
S
R
R
V
K
A
Q
T
Site 39
T278
S
R
R
V
K
A
Q
T
F
A
E
R
R
E
R
Site 40
S286
F
A
E
R
R
E
R
S
F
S
R
S
W
S
D
Site 41
S288
E
R
R
E
R
S
F
S
R
S
W
S
D
P
T
Site 42
S290
R
E
R
S
F
S
R
S
W
S
D
P
T
P
M
Site 43
S292
R
S
F
S
R
S
W
S
D
P
T
P
M
K
A
Site 44
T295
S
R
S
W
S
D
P
T
P
M
K
A
D
T
S
Site 45
T301
P
T
P
M
K
A
D
T
S
H
D
S
R
D
S
Site 46
S302
T
P
M
K
A
D
T
S
H
D
S
R
D
S
S
Site 47
S305
K
A
D
T
S
H
D
S
R
D
S
S
D
L
Q
Site 48
S308
T
S
H
D
S
R
D
S
S
D
L
Q
S
S
H
Site 49
S309
S
H
D
S
R
D
S
S
D
L
Q
S
S
H
C
Site 50
S313
R
D
S
S
D
L
Q
S
S
H
C
T
L
D
E
Site 51
T317
D
L
Q
S
S
H
C
T
L
D
E
A
F
E
D
Site 52
T329
F
E
D
L
D
W
D
T
E
K
G
L
E
A
V
Site 53
S353
P
K
V
M
L
I
S
S
K
V
P
K
A
E
Y
Site 54
Y360
S
K
V
P
K
A
E
Y
I
P
T
I
I
R
R
Site 55
T363
P
K
A
E
Y
I
P
T
I
I
R
R
D
D
P
Site 56
T383
L
Y
D
H
E
H
A
T
F
E
D
I
L
E
E
Site 57
Y398
I
E
R
K
L
N
V
Y
H
K
G
A
K
I
W
Site 58
Y419
Q
G
G
P
G
H
L
Y
L
L
K
N
K
V
A
Site 59
S449
K
R
L
S
R
L
M
S
K
V
N
P
E
P
N
Site 60
T483
Q
N
L
R
T
L
M
T
P
Y
R
V
T
F
E
Site 61
S491
P
Y
R
V
T
F
E
S
P
L
E
L
S
A
Q
Site 62
S496
F
E
S
P
L
E
L
S
A
Q
G
K
Q
M
I
Site 63
T505
Q
G
K
Q
M
I
E
T
Y
F
D
F
R
L
Y
Site 64
Y506
G
K
Q
M
I
E
T
Y
F
D
F
R
L
Y
R
Site 65
Y512
T
Y
F
D
F
R
L
Y
R
L
W
K
S
R
Q
Site 66
S517
R
L
Y
R
L
W
K
S
R
Q
H
S
K
L
L
Site 67
S521
L
W
K
S
R
Q
H
S
K
L
L
D
F
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation