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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPTN
Full Name:
Repetin
Alias:
Type:
Mass (Da):
90713
Number AA:
784
UniProt ID:
Q6XPR3
International Prot ID:
IPI00455626
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005578
GO:0031012
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
V
I
D
V
F
H
K
Y
A
K
G
N
G
D
C
Site 2
T53
Q
R
P
N
D
P
E
T
V
E
T
I
L
N
L
Site 3
T56
N
D
P
E
T
V
E
T
I
L
N
L
L
D
Q
Site 4
S93
Y
H
K
L
D
N
K
S
H
G
G
R
T
S
Q
Site 5
S99
K
S
H
G
G
R
T
S
Q
Q
E
R
G
Q
E
Site 6
S132
H
E
E
E
R
Q
N
S
H
H
S
Q
P
E
R
Site 7
S135
E
R
Q
N
S
H
H
S
Q
P
E
R
Q
D
G
Site 8
S144
P
E
R
Q
D
G
D
S
H
H
G
Q
P
E
R
Site 9
S156
P
E
R
Q
D
R
D
S
H
H
G
Q
S
E
K
Site 10
S168
S
E
K
Q
D
R
D
S
H
H
S
Q
P
E
R
Site 11
S171
Q
D
R
D
S
H
H
S
Q
P
E
R
Q
D
R
Site 12
S180
P
E
R
Q
D
R
D
S
H
H
N
Q
S
E
R
Site 13
S185
R
D
S
H
H
N
Q
S
E
R
Q
D
K
D
F
Site 14
S193
E
R
Q
D
K
D
F
S
F
D
Q
S
E
R
Q
Site 15
S197
K
D
F
S
F
D
Q
S
E
R
Q
S
Q
D
S
Site 16
S201
F
D
Q
S
E
R
Q
S
Q
D
S
S
S
G
K
Site 17
S204
S
E
R
Q
S
Q
D
S
S
S
G
K
K
V
S
Site 18
S205
E
R
Q
S
Q
D
S
S
S
G
K
K
V
S
H
Site 19
S206
R
Q
S
Q
D
S
S
S
G
K
K
V
S
H
K
Site 20
S211
S
S
S
G
K
K
V
S
H
K
S
T
S
G
Q
Site 21
S214
G
K
K
V
S
H
K
S
T
S
G
Q
A
K
W
Site 22
Y240
K
P
I
Q
D
S
H
Y
G
Q
S
E
R
H
T
Site 23
S243
Q
D
S
H
Y
G
Q
S
E
R
H
T
Q
Q
S
Site 24
T247
Y
G
Q
S
E
R
H
T
Q
Q
S
E
T
L
G
Site 25
S250
S
E
R
H
T
Q
Q
S
E
T
L
G
Q
A
S
Site 26
T252
R
H
T
Q
Q
S
E
T
L
G
Q
A
S
H
F
Site 27
T262
Q
A
S
H
F
N
Q
T
N
Q
Q
K
S
G
S
Site 28
S267
N
Q
T
N
Q
Q
K
S
G
S
Y
C
G
Q
S
Site 29
S269
T
N
Q
Q
K
S
G
S
Y
C
G
Q
S
E
R
Site 30
S274
S
G
S
Y
C
G
Q
S
E
R
L
G
Q
E
L
Site 31
T286
Q
E
L
G
C
G
Q
T
D
R
Q
G
Q
S
S
Site 32
S292
Q
T
D
R
Q
G
Q
S
S
H
Y
G
Q
T
D
Site 33
S293
T
D
R
Q
G
Q
S
S
H
Y
G
Q
T
D
R
Site 34
S304
Q
T
D
R
Q
D
Q
S
Y
H
Y
G
Q
T
D
Site 35
Y305
T
D
R
Q
D
Q
S
Y
H
Y
G
Q
T
D
R
Site 36
S316
Q
T
D
R
Q
G
Q
S
S
H
Y
S
Q
T
D
Site 37
S317
T
D
R
Q
G
Q
S
S
H
Y
S
Q
T
D
R
Site 38
S320
Q
G
Q
S
S
H
Y
S
Q
T
D
R
Q
G
Q
Site 39
T322
Q
S
S
H
Y
S
Q
T
D
R
Q
G
Q
S
S
Site 40
S328
Q
T
D
R
Q
G
Q
S
S
H
Y
S
Q
P
D
Site 41
S329
T
D
R
Q
G
Q
S
S
H
Y
S
Q
P
D
R
Site 42
Y331
R
Q
G
Q
S
S
H
Y
S
Q
P
D
R
Q
G
Site 43
S332
Q
G
Q
S
S
H
Y
S
Q
P
D
R
Q
G
Q
Site 44
S340
Q
P
D
R
Q
G
Q
S
S
H
Y
G
Q
M
D
Site 45
S341
P
D
R
Q
G
Q
S
S
H
Y
G
Q
M
D
R
Site 46
Y353
M
D
R
K
G
Q
C
Y
H
Y
D
Q
T
N
R
Site 47
Y355
R
K
G
Q
C
Y
H
Y
D
Q
T
N
R
Q
G
Site 48
S365
T
N
R
Q
G
Q
G
S
H
Y
S
Q
P
N
R
Site 49
Y367
R
Q
G
Q
G
S
H
Y
S
Q
P
N
R
Q
G
Site 50
S368
Q
G
Q
G
S
H
Y
S
Q
P
N
R
Q
G
Q
Site 51
S377
P
N
R
Q
G
Q
S
S
H
Y
G
Q
P
D
T
Site 52
Y379
R
Q
G
Q
S
S
H
Y
G
Q
P
D
T
Q
D
Site 53
T384
S
H
Y
G
Q
P
D
T
Q
D
Q
S
S
H
Y
Site 54
S389
P
D
T
Q
D
Q
S
S
H
Y
G
Q
T
D
R
Site 55
T394
Q
S
S
H
Y
G
Q
T
D
R
Q
D
Q
S
S
Site 56
S400
Q
T
D
R
Q
D
Q
S
S
H
Y
G
Q
T
E
Site 57
S401
T
D
R
Q
D
Q
S
S
H
Y
G
Q
T
E
R
Site 58
T406
Q
S
S
H
Y
G
Q
T
E
R
Q
G
Q
S
S
Site 59
S412
Q
T
E
R
Q
G
Q
S
S
H
Y
S
Q
M
D
Site 60
S413
T
E
R
Q
G
Q
S
S
H
Y
S
Q
M
D
R
Site 61
Y415
R
Q
G
Q
S
S
H
Y
S
Q
M
D
R
Q
G
Site 62
S416
Q
G
Q
S
S
H
Y
S
Q
M
D
R
Q
G
Q
Site 63
S425
M
D
R
Q
G
Q
G
S
H
Y
G
Q
T
D
R
Site 64
T430
Q
G
S
H
Y
G
Q
T
D
R
Q
G
Q
S
S
Site 65
S437
T
D
R
Q
G
Q
S
S
H
Y
G
Q
P
D
R
Site 66
Y439
R
Q
G
Q
S
S
H
Y
G
Q
P
D
R
Q
G
Site 67
S449
P
D
R
Q
G
Q
N
S
H
Y
G
Q
T
D
R
Site 68
T466
Q
S
S
H
Y
G
Q
T
D
R
Q
G
Q
S
S
Site 69
S473
T
D
R
Q
G
Q
S
S
H
Y
S
Q
P
D
K
Site 70
Y475
R
Q
G
Q
S
S
H
Y
S
Q
P
D
K
Q
G
Site 71
S476
Q
G
Q
S
S
H
Y
S
Q
P
D
K
Q
G
Q
Site 72
S484
Q
P
D
K
Q
G
Q
S
S
H
Y
G
K
I
D
Site 73
Y497
I
D
R
Q
D
Q
S
Y
H
Y
G
Q
P
D
G
Site 74
Y499
R
Q
D
Q
S
Y
H
Y
G
Q
P
D
G
Q
G
Site 75
S509
P
D
G
Q
G
Q
S
S
H
Y
G
Q
T
D
R
Site 76
S520
Q
T
D
R
Q
G
Q
S
F
H
Y
G
Q
P
D
Site 77
Y523
R
Q
G
Q
S
F
H
Y
G
Q
P
D
R
Q
G
Site 78
S532
Q
P
D
R
Q
G
Q
S
S
H
Y
S
Q
M
D
Site 79
S533
P
D
R
Q
G
Q
S
S
H
Y
S
Q
M
D
R
Site 80
S545
M
D
R
Q
G
Q
S
S
H
Y
G
Q
T
D
R
Site 81
Y569
T
D
R
Q
G
Q
S
Y
H
Y
G
Q
T
D
R
Site 82
S581
T
D
R
Q
G
Q
S
S
H
Y
I
Q
S
Q
T
Site 83
Y583
R
Q
G
Q
S
S
H
Y
I
Q
S
Q
T
G
E
Site 84
S586
Q
S
S
H
Y
I
Q
S
Q
T
G
E
I
Q
G
Site 85
Y597
E
I
Q
G
Q
N
K
Y
F
Q
G
T
E
G
T
Site 86
S608
T
E
G
T
R
K
A
S
Y
V
E
Q
S
G
R
Site 87
Y609
E
G
T
R
K
A
S
Y
V
E
Q
S
G
R
S
Site 88
S613
K
A
S
Y
V
E
Q
S
G
R
S
G
R
L
S
Site 89
S616
Y
V
E
Q
S
G
R
S
G
R
L
S
Q
Q
T
Site 90
S620
S
G
R
S
G
R
L
S
Q
Q
T
P
G
Q
E
Site 91
T623
S
G
R
L
S
Q
Q
T
P
G
Q
E
G
Y
Q
Site 92
Y629
Q
T
P
G
Q
E
G
Y
Q
N
Q
G
Q
G
F
Site 93
S638
N
Q
G
Q
G
F
Q
S
R
D
S
Q
Q
N
G
Site 94
S641
Q
G
F
Q
S
R
D
S
Q
Q
N
G
H
Q
V
Site 95
S681
H
K
G
R
D
W
Q
S
C
S
S
E
Q
G
H
Site 96
S683
G
R
D
W
Q
S
C
S
S
E
Q
G
H
R
Q
Site 97
S696
R
Q
A
Q
T
R
Q
S
H
G
E
G
L
S
H
Site 98
S702
Q
S
H
G
E
G
L
S
H
W
A
E
E
E
Q
Site 99
S718
H
Q
T
W
D
R
H
S
H
E
S
Q
E
G
P
Site 100
S721
W
D
R
H
S
H
E
S
Q
E
G
P
C
G
T
Site 101
T728
S
Q
E
G
P
C
G
T
Q
D
R
R
T
H
K
Site 102
T733
C
G
T
Q
D
R
R
T
H
K
D
E
Q
N
H
Site 103
T747
H
Q
R
R
D
R
Q
T
H
E
H
E
Q
S
H
Site 104
S753
Q
T
H
E
H
E
Q
S
H
Q
R
R
D
R
Q
Site 105
T761
H
Q
R
R
D
R
Q
T
H
E
D
K
Q
N
R
Site 106
T775
R
Q
R
R
D
R
Q
T
H
E
D
E
Q
N
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation