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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT10
Full Name:
Synaptotagmin-10
Alias:
Synaptotagmin X; SytX
Type:
Membrane, Synapse, Cytoplasmic vesicle, Cell junction, Integral membrane, Synaptic vesicle protein
Mass (Da):
59127
Number AA:
523
UniProt ID:
Q6XYQ8
International Prot ID:
IPI00395601
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0008021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Synaptotagmin-10 pan-specific antibody AB-NN344-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN344-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
H
K
E
D
G
V
N
S
L
C
Q
K
A
L
H
Site 2
S44
I
F
P
R
D
R
G
S
Q
G
G
S
S
T
D
Site 3
S48
D
R
G
S
Q
G
G
S
S
T
D
I
S
V
S
Site 4
S49
R
G
S
Q
G
G
S
S
T
D
I
S
V
S
L
Site 5
T50
G
S
Q
G
G
S
S
T
D
I
S
V
S
L
L
Site 6
T90
C
W
K
S
K
P
V
T
S
N
I
T
T
L
P
Site 7
T95
P
V
T
S
N
I
T
T
L
P
Q
S
I
S
S
Site 8
S99
N
I
T
T
L
P
Q
S
I
S
S
A
P
T
E
Site 9
S101
T
T
L
P
Q
S
I
S
S
A
P
T
E
V
F
Site 10
T105
Q
S
I
S
S
A
P
T
E
V
F
E
T
E
E
Site 11
T110
A
P
T
E
V
F
E
T
E
E
K
K
E
I
K
Site 12
S134
I
E
P
A
I
K
I
S
H
T
S
P
D
I
P
Site 13
T136
P
A
I
K
I
S
H
T
S
P
D
I
P
A
E
Site 14
S137
A
I
K
I
S
H
T
S
P
D
I
P
A
E
V
Site 15
T163
A
R
V
Q
R
Q
I
T
E
P
T
S
S
T
R
Site 16
S167
R
Q
I
T
E
P
T
S
S
T
R
H
S
S
F
Site 17
S168
Q
I
T
E
P
T
S
S
T
R
H
S
S
F
R
Site 18
S172
P
T
S
S
T
R
H
S
S
F
R
R
H
L
P
Site 19
S173
T
S
S
T
R
H
S
S
F
R
R
H
L
P
R
Site 20
S185
L
P
R
Q
M
Q
V
S
S
V
D
F
S
M
G
Site 21
S186
P
R
Q
M
Q
V
S
S
V
D
F
S
M
G
T
Site 22
T202
P
V
L
Q
R
G
E
T
T
T
S
I
G
R
I
Site 23
T203
V
L
Q
R
G
E
T
T
T
S
I
G
R
I
K
Site 24
T204
L
Q
R
G
E
T
T
T
S
I
G
R
I
K
P
Site 25
S205
Q
R
G
E
T
T
T
S
I
G
R
I
K
P
E
Site 26
Y214
G
R
I
K
P
E
L
Y
K
Q
K
S
V
D
S
Site 27
S218
P
E
L
Y
K
Q
K
S
V
D
S
E
G
N
Q
Site 28
Y243
N
F
T
L
Q
Y
D
Y
E
N
E
L
L
V
V
Site 29
T264
D
L
P
A
K
D
F
T
G
T
S
D
P
Y
V
Site 30
S267
A
K
D
F
T
G
T
S
D
P
Y
V
K
M
Y
Site 31
Y270
F
T
G
T
S
D
P
Y
V
K
M
Y
L
L
P
Site 32
Y274
S
D
P
Y
V
K
M
Y
L
L
P
D
R
K
K
Site 33
T285
D
R
K
K
K
F
Q
T
R
V
H
R
K
T
L
Site 34
T291
Q
T
R
V
H
R
K
T
L
N
P
L
F
D
E
Site 35
Y306
T
F
Q
F
P
V
A
Y
D
Q
L
S
N
R
K
Site 36
S310
P
V
A
Y
D
Q
L
S
N
R
K
L
H
F
S
Site 37
S317
S
N
R
K
L
H
F
S
V
Y
D
F
D
R
F
Site 38
Y319
R
K
L
H
F
S
V
Y
D
F
D
R
F
S
R
Site 39
S345
L
F
E
V
S
D
L
S
R
E
A
T
V
W
K
Site 40
T349
S
D
L
S
R
E
A
T
V
W
K
D
I
H
C
Site 41
T396
N
L
K
A
M
D
I
T
G
S
S
D
P
Y
V
Site 42
S399
A
M
D
I
T
G
S
S
D
P
Y
V
K
V
S
Site 43
S406
S
D
P
Y
V
K
V
S
L
M
C
E
G
R
R
Site 44
T419
R
R
L
K
K
R
K
T
T
T
K
K
N
T
L
Site 45
T420
R
L
K
K
R
K
T
T
T
K
K
N
T
L
N
Site 46
T425
K
T
T
T
K
K
N
T
L
N
P
V
Y
N
E
Site 47
Y430
K
N
T
L
N
P
V
Y
N
E
A
I
I
F
D
Site 48
Y455
L
S
I
A
V
M
D
Y
D
R
V
G
H
N
E
Site 49
T493
A
Y
H
R
K
P
I
T
H
W
H
P
L
L
E
Site 50
T506
L
E
L
P
G
R
A
T
S
F
D
S
Q
G
S
Site 51
S507
E
L
P
G
R
A
T
S
F
D
S
Q
G
S
C
Site 52
S510
G
R
A
T
S
F
D
S
Q
G
S
C
P
S
P
Site 53
S513
T
S
F
D
S
Q
G
S
C
P
S
P
K
P
P
Site 54
S516
D
S
Q
G
S
C
P
S
P
K
P
P
S
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation