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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPI
Full Name:
Lipase member I
Alias:
EC 3.1.1.-; LPD lipase; LPDL; Membrane-associated phosphatidic acid-selective phospholipase A1-beta; MPA-PLA1 beta
Type:
Phospholipase
Mass (Da):
52992
Number AA:
460
UniProt ID:
Q6XZB0
International Prot ID:
IPI00395604
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
GO:0016042
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
K
R
P
C
L
E
F
S
Q
L
S
V
K
D
S
Site 2
S28
C
L
E
F
S
Q
L
S
V
K
D
S
F
R
D
Site 3
S32
S
Q
L
S
V
K
D
S
F
R
D
L
F
I
P
Site 4
T43
L
F
I
P
R
I
E
T
I
L
M
M
Y
T
R
Site 5
Y48
I
E
T
I
L
M
M
Y
T
R
N
N
L
N
C
Site 6
T49
E
T
I
L
M
M
Y
T
R
N
N
L
N
C
A
Site 7
S65
P
L
F
E
Q
N
N
S
L
N
V
N
F
N
T
Site 8
S88
H
G
Y
R
P
V
G
S
I
P
L
W
L
Q
N
Site 9
T118
V
D
W
S
R
G
A
T
T
F
I
Y
N
R
A
Site 10
Y122
R
G
A
T
T
F
I
Y
N
R
A
V
K
N
T
Site 11
S135
N
T
R
K
V
A
V
S
L
S
V
H
I
K
N
Site 12
S149
N
L
L
K
H
G
A
S
L
D
N
F
H
F
I
Site 13
T180
H
G
Q
L
G
R
I
T
G
L
D
P
A
G
P
Site 14
S190
D
P
A
G
P
R
F
S
R
K
P
P
Y
S
R
Site 15
Y195
R
F
S
R
K
P
P
Y
S
R
L
D
Y
T
D
Site 16
S196
F
S
R
K
P
P
Y
S
R
L
D
Y
T
D
A
Site 17
Y200
P
P
Y
S
R
L
D
Y
T
D
A
K
F
V
D
Site 18
T201
P
Y
S
R
L
D
Y
T
D
A
K
F
V
D
V
Site 19
S213
V
D
V
I
H
S
D
S
N
G
L
G
I
Q
E
Site 20
Y228
P
L
G
H
I
D
F
Y
P
N
G
G
N
K
Q
Site 21
S241
K
Q
P
G
C
P
K
S
I
F
S
G
I
Q
F
Site 22
Y278
I
S
F
P
C
R
S
Y
K
D
Y
K
T
S
L
Site 23
Y281
P
C
R
S
Y
K
D
Y
K
T
S
L
C
V
D
Site 24
T283
R
S
Y
K
D
Y
K
T
S
L
C
V
D
C
D
Site 25
Y302
K
S
C
P
R
L
G
Y
Q
A
K
L
F
K
G
Site 26
T323
E
G
R
P
L
R
T
T
V
F
L
D
T
S
G
Site 27
T328
R
T
T
V
F
L
D
T
S
G
T
Y
P
F
C
Site 28
S354
D
K
T
M
M
D
G
S
F
S
F
K
L
L
N
Site 29
Y372
M
I
E
E
P
R
L
Y
E
K
N
K
P
F
Y
Site 30
Y391
V
K
I
L
A
Q
F
Y
N
D
F
V
N
I
S
Site 31
T403
N
I
S
S
I
G
L
T
Y
F
Q
S
S
N
L
Site 32
Y404
I
S
S
I
G
L
T
Y
F
Q
S
S
N
L
Q
Site 33
S407
I
G
L
T
Y
F
Q
S
S
N
L
Q
C
S
T
Site 34
S426
I
Q
R
L
M
L
K
S
L
T
Y
P
E
R
P
Site 35
T428
R
L
M
L
K
S
L
T
Y
P
E
R
P
P
L
Site 36
Y429
L
M
L
K
S
L
T
Y
P
E
R
P
P
L
C
Site 37
Y438
E
R
P
P
L
C
R
Y
N
I
V
L
K
D
R
Site 38
T454
E
V
F
L
N
P
N
T
C
T
P
K
N
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation