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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNMBP
Full Name:
Dynamin-binding protein
Alias:
Dynamin binding protein; KIAA1010; Scaffold protein Tuba; TUBA
Type:
Adapter/scaffold protein
Mass (Da):
177347
Number AA:
1577
UniProt ID:
Q6XZF7
International Prot ID:
IPI00174025
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005737
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0005083
GO:0005085
GO:0005088
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0007165
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T48
L
G
K
K
E
D
V
T
G
Q
F
P
S
S
F
Site 2
S128
V
R
E
L
C
L
S
S
Q
S
R
Q
W
H
S
Site 3
S130
E
L
C
L
S
S
Q
S
R
Q
W
H
S
Q
S
Site 4
S135
S
Q
S
R
Q
W
H
S
Q
S
A
L
F
Q
I
Site 5
T207
E
L
L
G
P
L
R
T
V
D
E
S
V
S
S
Site 6
S211
P
L
R
T
V
D
E
S
V
S
S
G
N
Q
D
Site 7
T228
I
V
N
G
E
V
D
T
P
V
G
E
E
E
I
Site 8
T246
E
D
E
E
E
P
G
T
Y
G
V
A
L
Y
R
Site 9
Y247
D
E
E
E
P
G
T
Y
G
V
A
L
Y
R
F
Site 10
T275
D
K
I
R
I
L
A
T
L
E
D
G
W
L
E
Site 11
S284
E
D
G
W
L
E
G
S
L
K
G
R
T
G
I
Site 12
T303
F
V
K
L
C
P
D
T
R
V
E
E
T
M
A
Site 13
S316
M
A
L
P
Q
E
G
S
L
A
R
I
P
E
T
Site 14
T323
S
L
A
R
I
P
E
T
S
L
D
C
L
E
N
Site 15
S324
L
A
R
I
P
E
T
S
L
D
C
L
E
N
T
Site 16
T331
S
L
D
C
L
E
N
T
L
G
V
E
E
Q
R
Site 17
T341
V
E
E
Q
R
H
E
T
S
D
H
E
A
E
E
Site 18
S342
E
E
Q
R
H
E
T
S
D
H
E
A
E
E
P
Site 19
S354
E
E
P
D
C
I
I
S
E
A
P
T
S
P
L
Site 20
S359
I
I
S
E
A
P
T
S
P
L
G
H
L
T
S
Site 21
S366
S
P
L
G
H
L
T
S
E
Y
D
T
D
R
N
Site 22
Y368
L
G
H
L
T
S
E
Y
D
T
D
R
N
S
Y
Site 23
T370
H
L
T
S
E
Y
D
T
D
R
N
S
Y
Q
D
Site 24
S374
E
Y
D
T
D
R
N
S
Y
Q
D
E
D
T
A
Site 25
Y375
Y
D
T
D
R
N
S
Y
Q
D
E
D
T
A
G
Site 26
T380
N
S
Y
Q
D
E
D
T
A
G
G
P
P
R
S
Site 27
S387
T
A
G
G
P
P
R
S
P
G
V
E
W
E
M
Site 28
T398
E
W
E
M
P
L
A
T
D
S
P
T
S
D
P
Site 29
S400
E
M
P
L
A
T
D
S
P
T
S
D
P
T
E
Site 30
T402
P
L
A
T
D
S
P
T
S
D
P
T
E
V
V
Site 31
S403
L
A
T
D
S
P
T
S
D
P
T
E
V
V
N
Site 32
T406
D
S
P
T
S
D
P
T
E
V
V
N
G
I
S
Site 33
S414
E
V
V
N
G
I
S
S
Q
P
Q
V
P
F
H
Site 34
S427
F
H
P
N
L
Q
K
S
Q
Y
Y
S
T
V
G
Site 35
Y429
P
N
L
Q
K
S
Q
Y
Y
S
T
V
G
G
S
Site 36
Y430
N
L
Q
K
S
Q
Y
Y
S
T
V
G
G
S
H
Site 37
S431
L
Q
K
S
Q
Y
Y
S
T
V
G
G
S
H
P
Site 38
T432
Q
K
S
Q
Y
Y
S
T
V
G
G
S
H
P
H
Site 39
S436
Y
Y
S
T
V
G
G
S
H
P
H
S
E
Q
Y
Site 40
S440
V
G
G
S
H
P
H
S
E
Q
Y
P
D
L
L
Site 41
Y443
S
H
P
H
S
E
Q
Y
P
D
L
L
P
L
E
Site 42
T453
L
L
P
L
E
A
R
T
R
D
Y
A
S
L
P
Site 43
Y456
L
E
A
R
T
R
D
Y
A
S
L
P
P
K
R
Site 44
S458
A
R
T
R
D
Y
A
S
L
P
P
K
R
M
Y
Site 45
Y465
S
L
P
P
K
R
M
Y
S
Q
L
K
T
L
Q
Site 46
S466
L
P
P
K
R
M
Y
S
Q
L
K
T
L
Q
K
Site 47
T470
R
M
Y
S
Q
L
K
T
L
Q
K
P
V
L
P
Site 48
Y479
Q
K
P
V
L
P
L
Y
R
G
S
S
V
S
A
Site 49
S483
L
P
L
Y
R
G
S
S
V
S
A
S
R
V
V
Site 50
S485
L
Y
R
G
S
S
V
S
A
S
R
V
V
K
P
Site 51
S487
R
G
S
S
V
S
A
S
R
V
V
K
P
R
Q
Site 52
S495
R
V
V
K
P
R
Q
S
S
P
Q
L
H
N
L
Site 53
S496
V
V
K
P
R
Q
S
S
P
Q
L
H
N
L
A
Site 54
S504
P
Q
L
H
N
L
A
S
Y
T
K
K
H
H
T
Site 55
T511
S
Y
T
K
K
H
H
T
S
S
V
Y
S
I
S
Site 56
S512
Y
T
K
K
H
H
T
S
S
V
Y
S
I
S
E
Site 57
S513
T
K
K
H
H
T
S
S
V
Y
S
I
S
E
R
Site 58
Y515
K
H
H
T
S
S
V
Y
S
I
S
E
R
L
E
Site 59
S516
H
H
T
S
S
V
Y
S
I
S
E
R
L
E
M
Site 60
S518
T
S
S
V
Y
S
I
S
E
R
L
E
M
K
P
Site 61
S540
V
M
E
A
A
T
H
S
Q
G
D
G
S
T
D
Site 62
S545
T
H
S
Q
G
D
G
S
T
D
L
D
S
K
L
Site 63
T546
H
S
Q
G
D
G
S
T
D
L
D
S
K
L
T
Site 64
S550
D
G
S
T
D
L
D
S
K
L
T
Q
Q
L
I
Site 65
S562
Q
L
I
E
F
E
K
S
L
A
G
P
G
T
E
Site 66
T568
K
S
L
A
G
P
G
T
E
P
D
K
I
L
R
Site 67
S578
D
K
I
L
R
H
F
S
I
M
D
F
N
S
E
Site 68
S584
F
S
I
M
D
F
N
S
E
K
D
I
V
R
G
Site 69
S592
E
K
D
I
V
R
G
S
S
K
L
I
T
E
Q
Site 70
S593
K
D
I
V
R
G
S
S
K
L
I
T
E
Q
E
Site 71
T597
R
G
S
S
K
L
I
T
E
Q
E
L
P
E
R
Site 72
T617
P
P
P
P
R
P
C
T
P
V
S
T
S
P
H
Site 73
S620
P
R
P
C
T
P
V
S
T
S
P
H
L
L
V
Site 74
S622
P
C
T
P
V
S
T
S
P
H
L
L
V
D
Q
Site 75
S642
P
P
L
V
V
R
P
S
R
P
A
P
L
P
P
Site 76
S650
R
P
A
P
L
P
P
S
A
Q
Q
R
T
N
A
Site 77
T655
P
P
S
A
Q
Q
R
T
N
A
V
S
P
K
L
Site 78
S659
Q
Q
R
T
N
A
V
S
P
K
L
L
S
R
H
Site 79
S664
A
V
S
P
K
L
L
S
R
H
R
P
T
C
E
Site 80
T669
L
L
S
R
H
R
P
T
C
E
T
L
E
K
E
Site 81
T672
R
H
R
P
T
C
E
T
L
E
K
E
G
P
G
Site 82
S684
G
P
G
H
M
G
R
S
L
D
Q
T
S
P
C
Site 83
T688
M
G
R
S
L
D
Q
T
S
P
C
P
L
V
L
Site 84
Y708
M
E
R
D
L
D
M
Y
S
R
A
Q
E
E
L
Site 85
S709
E
R
D
L
D
M
Y
S
R
A
Q
E
E
L
N
Site 86
S727
E
E
K
Q
D
E
S
S
R
A
E
T
L
E
D
Site 87
T731
D
E
S
S
R
A
E
T
L
E
D
L
K
F
C
Site 88
S740
E
D
L
K
F
C
E
S
N
I
E
S
L
N
M
Site 89
T756
L
Q
Q
L
R
E
M
T
L
L
S
S
Q
S
S
Site 90
S760
R
E
M
T
L
L
S
S
Q
S
S
S
L
V
A
Site 91
S769
S
S
S
L
V
A
P
S
G
S
V
S
A
E
N
Site 92
S771
S
L
V
A
P
S
G
S
V
S
A
E
N
P
E
Site 93
S773
V
A
P
S
G
S
V
S
A
E
N
P
E
Q
R
Site 94
T795
V
I
E
E
L
L
Q
T
E
R
D
Y
I
R
D
Site 95
Y799
L
L
Q
T
E
R
D
Y
I
R
D
L
E
M
C
Site 96
Y883
A
I
A
L
L
E
I
Y
E
K
D
E
K
I
Q
Site 97
S896
I
Q
K
H
L
Q
D
S
L
A
D
L
K
S
L
Site 98
S902
D
S
L
A
D
L
K
S
L
Y
N
E
W
G
C
Site 99
Y904
L
A
D
L
K
S
L
Y
N
E
W
G
C
T
N
Site 100
Y912
N
E
W
G
C
T
N
Y
I
N
L
G
S
F
L
Site 101
S939
L
L
M
E
L
L
N
S
T
P
E
S
H
P
D
Site 102
T940
L
M
E
L
L
N
S
T
P
E
S
H
P
D
K
Site 103
S943
L
L
N
S
T
P
E
S
H
P
D
K
V
P
L
Site 104
Y967
I
N
V
N
I
N
E
Y
K
R
R
K
D
L
V
Site 105
Y977
R
K
D
L
V
L
K
Y
R
K
G
D
E
D
S
Site 106
S984
Y
R
K
G
D
E
D
S
L
M
E
K
I
S
K
Site 107
S996
I
S
K
L
N
I
H
S
I
I
K
K
S
N
R
Site 108
S1001
I
H
S
I
I
K
K
S
N
R
V
S
S
H
L
Site 109
S1005
I
K
K
S
N
R
V
S
S
H
L
K
H
L
T
Site 110
S1006
K
K
S
N
R
V
S
S
H
L
K
H
L
T
G
Site 111
T1012
S
S
H
L
K
H
L
T
G
F
A
P
Q
I
K
Site 112
S1039
M
Q
E
R
L
I
K
S
F
I
R
D
L
S
L
Site 113
S1045
K
S
F
I
R
D
L
S
L
Y
L
Q
H
I
R
Site 114
Y1047
F
I
R
D
L
S
L
Y
L
Q
H
I
R
E
S
Site 115
Y1086
Q
F
E
R
V
H
R
Y
I
S
D
Q
L
F
T
Site 116
S1088
E
R
V
H
R
Y
I
S
D
Q
L
F
T
N
F
Site 117
S1105
R
T
E
R
L
V
I
S
P
L
N
Q
L
L
S
Site 118
S1112
S
P
L
N
Q
L
L
S
M
F
T
G
P
H
K
Site 119
Y1132
F
D
K
L
L
D
F
Y
N
C
T
E
R
A
E
Site 120
T1135
L
L
D
F
Y
N
C
T
E
R
A
E
K
L
K
Site 121
T1146
E
K
L
K
D
K
K
T
L
E
E
L
Q
S
A
Site 122
S1152
K
T
L
E
E
L
Q
S
A
R
N
N
Y
E
A
Site 123
Y1157
L
Q
S
A
R
N
N
Y
E
A
L
N
A
Q
L
Site 124
S1241
V
F
T
F
F
P
E
S
L
P
A
T
K
K
P
Site 125
T1245
F
P
E
S
L
P
A
T
K
K
P
F
E
R
K
Site 126
T1253
K
K
P
F
E
R
K
T
I
D
R
Q
S
A
R
Site 127
S1258
R
K
T
I
D
R
Q
S
A
R
K
P
L
L
G
Site 128
S1268
K
P
L
L
G
L
P
S
Y
M
L
Q
S
E
E
Site 129
S1279
Q
S
E
E
L
R
A
S
L
L
A
R
Y
P
P
Site 130
Y1284
R
A
S
L
L
A
R
Y
P
P
E
K
L
F
Q
Site 131
S1323
K
K
K
D
P
M
G
S
Q
N
R
W
L
I
D
Site 132
S1340
V
T
K
G
F
V
Y
S
S
F
L
K
P
Y
N
Site 133
S1341
T
K
G
F
V
Y
S
S
F
L
K
P
Y
N
P
Site 134
Y1346
Y
S
S
F
L
K
P
Y
N
P
R
R
S
H
S
Site 135
S1351
K
P
Y
N
P
R
R
S
H
S
D
A
S
V
G
Site 136
S1353
Y
N
P
R
R
S
H
S
D
A
S
V
G
S
H
Site 137
S1356
R
R
S
H
S
D
A
S
V
G
S
H
S
S
T
Site 138
S1359
H
S
D
A
S
V
G
S
H
S
S
T
E
S
E
Site 139
S1361
D
A
S
V
G
S
H
S
S
T
E
S
E
H
G
Site 140
S1362
A
S
V
G
S
H
S
S
T
E
S
E
H
G
S
Site 141
T1363
S
V
G
S
H
S
S
T
E
S
E
H
G
S
S
Site 142
S1365
G
S
H
S
S
T
E
S
E
H
G
S
S
S
P
Site 143
S1369
S
T
E
S
E
H
G
S
S
S
P
R
F
P
R
Site 144
S1370
T
E
S
E
H
G
S
S
S
P
R
F
P
R
Q
Site 145
S1371
E
S
E
H
G
S
S
S
P
R
F
P
R
Q
N
Site 146
S1379
P
R
F
P
R
Q
N
S
G
S
T
L
T
F
N
Site 147
S1381
F
P
R
Q
N
S
G
S
T
L
T
F
N
P
S
Site 148
T1382
P
R
Q
N
S
G
S
T
L
T
F
N
P
S
S
Site 149
T1384
Q
N
S
G
S
T
L
T
F
N
P
S
S
M
A
Site 150
S1393
N
P
S
S
M
A
V
S
F
T
S
G
S
C
Q
Site 151
S1396
S
M
A
V
S
F
T
S
G
S
C
Q
K
Q
P
Site 152
S1398
A
V
S
F
T
S
G
S
C
Q
K
Q
P
Q
D
Site 153
S1407
Q
K
Q
P
Q
D
A
S
P
P
P
K
E
C
D
Site 154
T1417
P
K
E
C
D
Q
G
T
L
S
A
S
L
N
P
Site 155
S1419
E
C
D
Q
G
T
L
S
A
S
L
N
P
S
N
Site 156
S1421
D
Q
G
T
L
S
A
S
L
N
P
S
N
S
E
Site 157
S1425
L
S
A
S
L
N
P
S
N
S
E
S
S
P
S
Site 158
S1427
A
S
L
N
P
S
N
S
E
S
S
P
S
R
C
Site 159
S1429
L
N
P
S
N
S
E
S
S
P
S
R
C
P
S
Site 160
S1430
N
P
S
N
S
E
S
S
P
S
R
C
P
S
D
Site 161
S1432
S
N
S
E
S
S
P
S
R
C
P
S
D
P
D
Site 162
S1436
S
S
P
S
R
C
P
S
D
P
D
S
T
S
Q
Site 163
S1440
R
C
P
S
D
P
D
S
T
S
Q
P
R
S
G
Site 164
T1441
C
P
S
D
P
D
S
T
S
Q
P
R
S
G
D
Site 165
S1442
P
S
D
P
D
S
T
S
Q
P
R
S
G
D
S
Site 166
S1446
D
S
T
S
Q
P
R
S
G
D
S
A
D
V
A
Site 167
T1460
A
R
D
V
K
Q
P
T
A
T
P
R
S
Y
R
Site 168
T1462
D
V
K
Q
P
T
A
T
P
R
S
Y
R
N
F
Site 169
S1465
Q
P
T
A
T
P
R
S
Y
R
N
F
R
H
P
Site 170
Y1466
P
T
A
T
P
R
S
Y
R
N
F
R
H
P
E
Site 171
Y1477
R
H
P
E
I
V
G
Y
S
V
P
G
R
N
G
Site 172
S1478
H
P
E
I
V
G
Y
S
V
P
G
R
N
G
Q
Site 173
S1486
V
P
G
R
N
G
Q
S
Q
D
L
V
K
G
C
Site 174
S1504
A
Q
A
P
E
D
R
S
T
E
P
D
G
S
E
Site 175
T1505
Q
A
P
E
D
R
S
T
E
P
D
G
S
E
A
Site 176
S1510
R
S
T
E
P
D
G
S
E
A
E
G
N
Q
V
Site 177
Y1518
E
A
E
G
N
Q
V
Y
F
A
V
Y
T
F
K
Site 178
S1533
A
R
N
P
N
E
L
S
V
S
A
N
Q
K
L
Site 179
S1535
N
P
N
E
L
S
V
S
A
N
Q
K
L
K
I
Site 180
Y1565
E
V
N
G
K
K
G
Y
V
P
S
N
Y
I
R
Site 181
S1568
G
K
K
G
Y
V
P
S
N
Y
I
R
K
T
E
Site 182
Y1570
K
G
Y
V
P
S
N
Y
I
R
K
T
E
Y
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation